CA2380317A1 - Synthetases humaines - Google Patents

Synthetases humaines Download PDF

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Publication number
CA2380317A1
CA2380317A1 CA002380317A CA2380317A CA2380317A1 CA 2380317 A1 CA2380317 A1 CA 2380317A1 CA 002380317 A CA002380317 A CA 002380317A CA 2380317 A CA2380317 A CA 2380317A CA 2380317 A1 CA2380317 A1 CA 2380317A1
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CA
Canada
Prior art keywords
seq
synt
polynucleotide
polypeptide
sequence
Prior art date
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Abandoned
Application number
CA002380317A
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English (en)
Inventor
Y. Tom Tang
Jennifer L. Hillman
Olga Bandman
Henry Yue
Mariah R. Baughn
Preeti Lal
Dyung Aina M. Lu
Purvi Shah
Yalda Azimzai
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Incyte Corp
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Individual
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Publication of CA2380317A1 publication Critical patent/CA2380317A1/fr
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93Ligases (6)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Abstract

L'invention concerne des synthétases humaines (SYNT) et des polynucléotides qui identifient et codent les SYNT. Elle concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. Elle concerne enfin des procédés de diagnostic, de traitement ou de prévention de troubles associés à l'expression des SYNT.
CA002380317A 1999-07-22 2000-07-20 Synthetases humaines Abandoned CA2380317A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US14499299P 1999-07-22 1999-07-22
US60/144,992 1999-07-22
US16885899P 1999-12-02 1999-12-02
US60/168,858 1999-12-02
PCT/US2000/019980 WO2001007628A2 (fr) 1999-07-22 2000-07-20 Synthetases humaines

Publications (1)

Publication Number Publication Date
CA2380317A1 true CA2380317A1 (fr) 2001-02-01

Family

ID=26842557

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002380317A Abandoned CA2380317A1 (fr) 1999-07-22 2000-07-20 Synthetases humaines

Country Status (5)

Country Link
EP (1) EP1200596A2 (fr)
JP (1) JP2003533967A (fr)
AU (1) AU6364700A (fr)
CA (1) CA2380317A1 (fr)
WO (1) WO2001007628A2 (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001090324A2 (fr) * 2000-05-19 2001-11-29 Millennium Pharmaceuticals, Inc. 32263 : une nouvelle enzyme a biotine et ses utilisations
US20090162363A1 (en) * 2003-08-07 2009-06-25 Sofia Patricia Becerra Pedf-r receptor and uses
WO2005118816A2 (fr) * 2004-05-27 2005-12-15 Karl-Franzens-Universität Graz Proteine deployant une activite de triglyceride-hydrolase
ES2579995T3 (es) * 2004-05-27 2016-08-18 Karl-Franzens-Universitat Graz Modulando la actividad de triglicérido hidrolasa
JP5265140B2 (ja) * 2007-06-14 2013-08-14 学校法人日本医科大学 卵巣癌の検出方法及び検出用キット
JP6066900B2 (ja) 2010-04-26 2017-01-25 エータイアー ファーマ, インコーポレイテッド システイニルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
AU2011248614B2 (en) 2010-04-27 2017-02-16 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl tRNA synthetases
CN103096910A (zh) 2010-04-27 2013-05-08 Atyr医药公司 与苏氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
CN103097524B (zh) 2010-04-28 2016-08-03 Atyr医药公司 与丙氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
US9034320B2 (en) 2010-04-29 2015-05-19 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Valyl-tRNA synthetases
AU2011248490B2 (en) 2010-04-29 2016-11-10 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Asparaginyl tRNA synthetases
WO2011139986A2 (fr) 2010-05-03 2011-11-10 Atyr Pharma, Inc. Découverte innovante de compositions thérapeutiques, de diagnostic et d'anticorps liées à des fragments protéiques d'arginyle-arnt synthétases
JP6008840B2 (ja) 2010-05-03 2016-10-19 エータイアー ファーマ, インコーポレイテッド フェニルアラニルαtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
CN103140233B (zh) 2010-05-03 2017-04-05 Atyr 医药公司 与甲硫氨酰‑tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现
US8946157B2 (en) 2010-05-03 2015-02-03 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of seryl-tRNA synthetases
CN103096909A (zh) 2010-05-04 2013-05-08 Atyr医药公司 与谷氨酰-脯氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
AU2011248101B2 (en) 2010-05-04 2016-10-20 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-tRNA synthetase complex
EP2568996B1 (fr) 2010-05-14 2017-10-04 aTyr Pharma, Inc. Compositions thérapeutique, diagnostique et à base d'anticorps contenant des fragments protéiques de phénylalanyl-bêta-arnt synthétases
JP6027965B2 (ja) 2010-05-17 2016-11-16 エータイアー ファーマ, インコーポレイテッド ロイシルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
EP2575856B1 (fr) 2010-05-27 2017-08-16 aTyr Pharma, Inc. Découverte innovante de compositions thérapeutiques, de diagnostic et d'anticorps liées à fragments protéiques de glutaminyl-arnt synthétases
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