CA2380317A1 - Synthetases humaines - Google Patents
Synthetases humaines Download PDFInfo
- Publication number
- CA2380317A1 CA2380317A1 CA002380317A CA2380317A CA2380317A1 CA 2380317 A1 CA2380317 A1 CA 2380317A1 CA 002380317 A CA002380317 A CA 002380317A CA 2380317 A CA2380317 A CA 2380317A CA 2380317 A1 CA2380317 A1 CA 2380317A1
- Authority
- CA
- Canada
- Prior art keywords
- seq
- synt
- polynucleotide
- polypeptide
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
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- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Gynecology & Obstetrics (AREA)
- Communicable Diseases (AREA)
- Psychiatry (AREA)
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Abstract
L'invention concerne des synthétases humaines (SYNT) et des polynucléotides qui identifient et codent les SYNT. Elle concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. Elle concerne enfin des procédés de diagnostic, de traitement ou de prévention de troubles associés à l'expression des SYNT.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14499299P | 1999-07-22 | 1999-07-22 | |
US60/144,992 | 1999-07-22 | ||
US16885899P | 1999-12-02 | 1999-12-02 | |
US60/168,858 | 1999-12-02 | ||
PCT/US2000/019980 WO2001007628A2 (fr) | 1999-07-22 | 2000-07-20 | Synthetases humaines |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2380317A1 true CA2380317A1 (fr) | 2001-02-01 |
Family
ID=26842557
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002380317A Abandoned CA2380317A1 (fr) | 1999-07-22 | 2000-07-20 | Synthetases humaines |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1200596A2 (fr) |
JP (1) | JP2003533967A (fr) |
AU (1) | AU6364700A (fr) |
CA (1) | CA2380317A1 (fr) |
WO (1) | WO2001007628A2 (fr) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001090324A2 (fr) * | 2000-05-19 | 2001-11-29 | Millennium Pharmaceuticals, Inc. | 32263 : une nouvelle enzyme a biotine et ses utilisations |
US20090162363A1 (en) * | 2003-08-07 | 2009-06-25 | Sofia Patricia Becerra | Pedf-r receptor and uses |
WO2005118816A2 (fr) * | 2004-05-27 | 2005-12-15 | Karl-Franzens-Universität Graz | Proteine deployant une activite de triglyceride-hydrolase |
ES2579995T3 (es) * | 2004-05-27 | 2016-08-18 | Karl-Franzens-Universitat Graz | Modulando la actividad de triglicérido hidrolasa |
JP5265140B2 (ja) * | 2007-06-14 | 2013-08-14 | 学校法人日本医科大学 | 卵巣癌の検出方法及び検出用キット |
JP6066900B2 (ja) | 2010-04-26 | 2017-01-25 | エータイアー ファーマ, インコーポレイテッド | システイニルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
AU2011248614B2 (en) | 2010-04-27 | 2017-02-16 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl tRNA synthetases |
CN103096910A (zh) | 2010-04-27 | 2013-05-08 | Atyr医药公司 | 与苏氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
CN103097524B (zh) | 2010-04-28 | 2016-08-03 | Atyr医药公司 | 与丙氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
US9034320B2 (en) | 2010-04-29 | 2015-05-19 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Valyl-tRNA synthetases |
AU2011248490B2 (en) | 2010-04-29 | 2016-11-10 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Asparaginyl tRNA synthetases |
WO2011139986A2 (fr) | 2010-05-03 | 2011-11-10 | Atyr Pharma, Inc. | Découverte innovante de compositions thérapeutiques, de diagnostic et d'anticorps liées à des fragments protéiques d'arginyle-arnt synthétases |
JP6008840B2 (ja) | 2010-05-03 | 2016-10-19 | エータイアー ファーマ, インコーポレイテッド | フェニルアラニルαtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
CN103140233B (zh) | 2010-05-03 | 2017-04-05 | Atyr 医药公司 | 与甲硫氨酰‑tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现 |
US8946157B2 (en) | 2010-05-03 | 2015-02-03 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of seryl-tRNA synthetases |
CN103096909A (zh) | 2010-05-04 | 2013-05-08 | Atyr医药公司 | 与谷氨酰-脯氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
AU2011248101B2 (en) | 2010-05-04 | 2016-10-20 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-tRNA synthetase complex |
EP2568996B1 (fr) | 2010-05-14 | 2017-10-04 | aTyr Pharma, Inc. | Compositions thérapeutique, diagnostique et à base d'anticorps contenant des fragments protéiques de phénylalanyl-bêta-arnt synthétases |
JP6027965B2 (ja) | 2010-05-17 | 2016-11-16 | エータイアー ファーマ, インコーポレイテッド | ロイシルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
EP2575856B1 (fr) | 2010-05-27 | 2017-08-16 | aTyr Pharma, Inc. | Découverte innovante de compositions thérapeutiques, de diagnostic et d'anticorps liées à fragments protéiques de glutaminyl-arnt synthétases |
EP2575857B1 (fr) | 2010-06-01 | 2018-01-24 | aTyr Pharma, Inc. | Découverte innovante de compositions thérapeutiques, diagnostiques, et d'anticorps associés à des fragments de protéine de lysyl-tarn synthétases |
KR20130102534A (ko) | 2010-07-12 | 2013-09-17 | 에이티와이알 파마, 인코포레이티드 | 히스티딜trna 합성효소의 단백질 단편에 관련된 치료적, 진단적, 및 항체 조성물의 혁신적 발견 |
US8999321B2 (en) | 2010-07-12 | 2015-04-07 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases |
WO2012009289A2 (fr) | 2010-07-12 | 2012-01-19 | Atyr Pharma, Inc. | Découverte innovante de compositions thérapeutiques, diagnostiques et d'anticorps relatives à des fragments protéiques d'aspartyl-arnt synthétases |
AU2011289831C1 (en) | 2010-07-12 | 2017-06-15 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases |
EP2608801B1 (fr) | 2010-08-25 | 2019-08-21 | aTyr Pharma, Inc. | Découverte innovante de compositions thérapeutiques, diagnostiques et d'anticorps associées à des fragments protéiniques des tyrosyl-arnt synthétases |
ES2645019T3 (es) | 2010-10-06 | 2017-12-01 | Atyr Pharma, Inc. | Descubrimiento innovador de composiciones terapéuticas, de diagnóstico y de anticuerpos relacionadas con fragmentos de proteínas de triptofanil-ARNt sintetasas |
WO2013022982A2 (fr) | 2011-08-09 | 2013-02-14 | Atyr Pharma, Inc. | Polypeptides tyrosyl-arnt synthétase pégylés |
US9816084B2 (en) | 2011-12-06 | 2017-11-14 | Atyr Pharma, Inc. | Aspartyl-tRNA synthetases |
US9822353B2 (en) | 2011-12-06 | 2017-11-21 | Atyr Pharma, Inc. | PEGylated aspartyl-tRNA synthetase polypeptides |
AU2012368189B2 (en) | 2011-12-29 | 2017-08-31 | Atyr Pharma, Inc. | Aspartyl-tRNA synthetase-Fc conjugates |
EP2970921B1 (fr) | 2013-03-15 | 2018-09-19 | aTyr Pharma, Inc. | Conjugués histidyl-arnt synthétase-région fc |
JP2020517638A (ja) | 2017-04-20 | 2020-06-18 | エータイアー ファーマ, インコーポレイテッド | 肺の炎症を治療するための組成物および方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5759833A (en) * | 1994-05-27 | 1998-06-02 | Cubist Pharmaceuticals, Inc. | Human isoleucyl-tRNA synthetase proteins, nucleic acids and tester strains comprising same |
US6423514B1 (en) * | 1996-04-22 | 2002-07-23 | Millennium Pharmaceuticals, Inc. | Mammalian hyaluronan synthases, nucleic acids and uses thereof |
GB9621486D0 (en) * | 1996-10-15 | 1996-12-04 | Isis Innovation | Oxygenase enzymes & method |
AU3395900A (en) * | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
-
2000
- 2000-07-20 AU AU63647/00A patent/AU6364700A/en not_active Abandoned
- 2000-07-20 JP JP2001512894A patent/JP2003533967A/ja active Pending
- 2000-07-20 WO PCT/US2000/019980 patent/WO2001007628A2/fr not_active Application Discontinuation
- 2000-07-20 EP EP00950556A patent/EP1200596A2/fr not_active Withdrawn
- 2000-07-20 CA CA002380317A patent/CA2380317A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU6364700A (en) | 2001-02-13 |
WO2001007628A2 (fr) | 2001-02-01 |
EP1200596A2 (fr) | 2002-05-02 |
JP2003533967A (ja) | 2003-11-18 |
WO2001007628A3 (fr) | 2001-08-16 |
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