CA2413810A1 - Aminoacyl arnt synthetases - Google Patents

Aminoacyl arnt synthetases Download PDF

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Publication number
CA2413810A1
CA2413810A1 CA002413810A CA2413810A CA2413810A1 CA 2413810 A1 CA2413810 A1 CA 2413810A1 CA 002413810 A CA002413810 A CA 002413810A CA 2413810 A CA2413810 A CA 2413810A CA 2413810 A1 CA2413810 A1 CA 2413810A1
Authority
CA
Canada
Prior art keywords
polypeptide
polynucleotide
atrs
seq
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002413810A
Other languages
English (en)
Inventor
Ernestine A. Lee
Y. Tom Tang
Dyung Aina M. Lu
Catherine M. Tribouley
Ameena R. Gandhi
Yan Lu
Mariah R. Baughn
Bridget A. Warren
Michael Thornton
Henry Yue
Jennifer L. Jackson
Chandra S. Arvizu
Vicki S. Elliott
Kavitha Thangavelu
Jayalaxmi Ramkumar
Narinder K. Chawla
Monique G. Yao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2413810A1 publication Critical patent/CA2413810A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Cette invention concerne des aminoacyl ARNt synthétases (ATRS) humaines et des polynucléotides qui identifient des ATRS et codent pour ces derniers. L'invention porte également sur des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. De plus, l'invention concerne des méthodes de diagnostic, de traitement et de prévention de troubles associés à une expression aberrante des ATRS.
CA002413810A 2000-07-07 2001-06-29 Aminoacyl arnt synthetases Abandoned CA2413810A1 (fr)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US21674800P 2000-07-07 2000-07-07
US60/216,748 2000-07-07
US21901900P 2000-07-18 2000-07-18
US60/219,019 2000-07-18
US22305800P 2000-08-04 2000-08-04
US60/223,058 2000-08-04
US23469300P 2000-09-21 2000-09-21
US60/234,693 2000-09-21
US23979700P 2000-10-11 2000-10-11
US60/239,797 2000-10-11
PCT/US2001/020723 WO2002004611A2 (fr) 2000-07-07 2001-06-29 Aminoacyl arnt synthetases

Publications (1)

Publication Number Publication Date
CA2413810A1 true CA2413810A1 (fr) 2002-01-17

Family

ID=27539739

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002413810A Abandoned CA2413810A1 (fr) 2000-07-07 2001-06-29 Aminoacyl arnt synthetases

Country Status (5)

Country Link
EP (1) EP1299546A2 (fr)
JP (1) JP2004516009A (fr)
AU (1) AU2001271620A1 (fr)
CA (1) CA2413810A1 (fr)
WO (1) WO2002004611A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090291465A1 (en) 2006-06-28 2009-11-26 Fundació Privada Parc Científic De Barcelona Screening Method for Identifying New Drugs
ES2622444T3 (es) 2008-06-11 2017-07-06 Atyr Pharma, Inc. Actividad trombopoyética de polipéptidos tirosil-ARNt sintetasa
US8828395B2 (en) 2009-12-11 2014-09-09 Atyr Pharma, Inc. Antibodies that bind tyrosyl-tRNA synthetases
US9029506B2 (en) 2010-08-25 2015-05-12 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of tyrosyl-tRNA synthetases
US9714419B2 (en) 2011-08-09 2017-07-25 Atyr Pharma, Inc. PEGylated tyrosyl-tRNA synthetase polypeptides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5759833A (en) * 1994-05-27 1998-06-02 Cubist Pharmaceuticals, Inc. Human isoleucyl-tRNA synthetase proteins, nucleic acids and tester strains comprising same
CN1297044A (zh) * 1999-11-22 2001-05-30 上海博容基因开发有限公司 一种新的多肽——人甲硫氨酰tRNA合成酶29和编码这种多肽的多核苷酸
WO2001053471A1 (fr) * 2000-01-24 2001-07-26 Smithkline Beecham Corporation Polypeptide metrs appartenant aux arnt-synthetases

Also Published As

Publication number Publication date
JP2004516009A (ja) 2004-06-03
WO2002004611A3 (fr) 2003-01-03
EP1299546A2 (fr) 2003-04-09
WO2002004611A2 (fr) 2002-01-17
AU2001271620A1 (en) 2002-01-21

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Legal Events

Date Code Title Description
FZDE Dead