CA2383927A1 - Proteines phosphatase et proteines kinase - Google Patents

Proteines phosphatase et proteines kinase Download PDF

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Publication number
CA2383927A1
CA2383927A1 CA002383927A CA2383927A CA2383927A1 CA 2383927 A1 CA2383927 A1 CA 2383927A1 CA 002383927 A CA002383927 A CA 002383927A CA 2383927 A CA2383927 A CA 2383927A CA 2383927 A1 CA2383927 A1 CA 2383927A1
Authority
CA
Canada
Prior art keywords
pphkp
polynucleotide
polypeptide
sequence
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002383927A
Other languages
English (en)
Inventor
Henry Yue
Y. Tom Tang
Olga Bandman
Jennifer L. Hillman
Mariah R. Baughn
Yalda Azimzai
Dyung Aina M. Lu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2383927A1 publication Critical patent/CA2383927A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Cette invention porte sur des protéines phosphatase et sur des protéines kinase (PPHKP) humaines, ainsi que sur des polynucléotides qui identifient et codent PPHKP. L'invention porte également sur des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. L'invention porte aussi sur des procédés de diagnostic, traitement ou prévention de pathologies associées à l'expression de PPHKP.
CA002383927A 1999-09-15 2000-09-14 Proteines phosphatase et proteines kinase Abandoned CA2383927A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15414199P 1999-09-15 1999-09-15
US60/154,141 1999-09-15
PCT/US2000/025515 WO2001020004A2 (fr) 1999-09-15 2000-09-14 Proteines phosphatase et proteines kinase

Publications (1)

Publication Number Publication Date
CA2383927A1 true CA2383927A1 (fr) 2001-03-22

Family

ID=22550173

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002383927A Abandoned CA2383927A1 (fr) 1999-09-15 2000-09-14 Proteines phosphatase et proteines kinase

Country Status (5)

Country Link
EP (1) EP1212436A2 (fr)
JP (1) JP2003509053A (fr)
AU (1) AU7829700A (fr)
CA (1) CA2383927A1 (fr)
WO (1) WO2001020004A2 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6730491B2 (en) 2000-02-29 2004-05-04 Millennium Pharmaceuticals, Inc. 2504, 15977, and 14760, novel protein kinase family members and uses therefor
CA2377662A1 (fr) * 1999-08-13 2001-02-22 Sugen, Inc. Nouvelles phosphatases de proteines et diagnostic et traitement des troubles lies a la phosphatase
WO2001073060A2 (fr) 2000-03-24 2001-10-04 Millennium Pharmaceuticals, Inc. 18221, nouveau phosphatase a specificite double et ses utilisations
EP1263970A1 (fr) * 2000-04-10 2002-12-11 MERCK PATENT GmbH Identification d'une phosphatase a specificite double: dusp-10
US6461846B2 (en) * 2000-05-30 2002-10-08 Pe Corporation Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
WO2002020732A2 (fr) * 2000-09-07 2002-03-14 Bayer Aktiengesellschaft Régulation d'enzyme humaine de type map kinase phosphatase
US6825021B2 (en) * 2000-09-19 2004-11-30 Ceptyr, Inc. DSP-15 dual-specificity phosphatase
WO2002026997A2 (fr) * 2000-09-26 2002-04-04 Ceptyr, Inc. Dsp-16, phosphatase a double specificite
AU2002228599A1 (en) * 2000-11-20 2002-06-03 Pe Corporation (Ny) Isolated human phosphatase proteins, nucleic acid molecules encoding them, and uses thereof
US7153678B2 (en) 2000-12-20 2006-12-26 Bristol-Myers Squibb Polynucleotides encoding the novel human phosphatase, RET31, and variants thereof
US6905827B2 (en) 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
EP1694701A2 (fr) * 2003-12-16 2006-08-30 Ares Trading S.A. Sous-unités de la phosphatase pp2a, leurs modulateurs et leur utilisation pour le traitement de troubles mentaux
JP2010535503A (ja) * 2007-08-10 2010-11-25 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ（エー＊エスティーエーアール） 癌の診断および治療のためのｖｈｚ
JP5756014B2 (ja) * 2008-08-08 2015-07-29 エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ（エイ・スター） がんの診断および治療のためのｖｈｚ
JP6472075B2 (ja) * 2015-02-26 2019-02-20 学校法人順天堂 Ｇｉｓｔの予後又は治療抵抗性の診断

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6346406B1 (en) * 1997-08-20 2002-02-12 University Of Medicine & Dentistry Of New Jersey Elongation factor-2 kinase (EF-2 kinase), and methods of use therefor

Also Published As

Publication number Publication date
WO2001020004A3 (fr) 2001-10-18
AU7829700A (en) 2001-04-17
EP1212436A2 (fr) 2002-06-12
JP2003509053A (ja) 2003-03-11
WO2001020004A2 (fr) 2001-03-22

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FZDE Dead