CA2380178A1 - Polypeptide dendrimers as unimolecular carriers of diagnostic imaging contrast agents, bioactive substances and drugs - Google Patents

Polypeptide dendrimers as unimolecular carriers of diagnostic imaging contrast agents, bioactive substances and drugs Download PDF

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Publication number
CA2380178A1
CA2380178A1 CA002380178A CA2380178A CA2380178A1 CA 2380178 A1 CA2380178 A1 CA 2380178A1 CA 002380178 A CA002380178 A CA 002380178A CA 2380178 A CA2380178 A CA 2380178A CA 2380178 A1 CA2380178 A1 CA 2380178A1
Authority
CA
Canada
Prior art keywords
gly
orn
polypeptide
dendrimer
dendrimers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002380178A
Other languages
English (en)
French (fr)
Inventor
Antonio Verdini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2380178A1 publication Critical patent/CA2380178A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/641Branched, dendritic or hypercomb peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA002380178A 1999-07-23 2000-07-21 Polypeptide dendrimers as unimolecular carriers of diagnostic imaging contrast agents, bioactive substances and drugs Abandoned CA2380178A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITFO99A000015 1999-07-23
IT1999FO000015A ITFO990015A1 (it) 1999-07-23 1999-07-23 "dendrimeri polipeptidici quali trasportatori unimolecolari di farmaci e sostanze biologicamente attive".
PCT/EP2000/007022 WO2001007469A2 (en) 1999-07-23 2000-07-21 Polypeptide dendrimers as unimolecular carriers of diagnostic imaging contrast agents, bioactive substances and drugs

Publications (1)

Publication Number Publication Date
CA2380178A1 true CA2380178A1 (en) 2001-02-01

Family

ID=11353680

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002380178A Abandoned CA2380178A1 (en) 1999-07-23 2000-07-21 Polypeptide dendrimers as unimolecular carriers of diagnostic imaging contrast agents, bioactive substances and drugs

Country Status (12)

Country Link
EP (1) EP1200461A2 (ja)
JP (1) JP2003506326A (ja)
CN (1) CN1364171A (ja)
AU (1) AU772167B2 (ja)
CA (1) CA2380178A1 (ja)
HU (1) HUP0201975A3 (ja)
IT (1) ITFO990015A1 (ja)
NO (1) NO20020333D0 (ja)
NZ (1) NZ517231A (ja)
PL (1) PL353273A1 (ja)
WO (1) WO2001007469A2 (ja)
ZA (1) ZA200201089B (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR032941A1 (es) 2001-03-05 2003-12-03 Shell Int Research Un procedimiento para preparar un aceite base lubricante y aceite base obtenido, con sus diversas utilizaciones
MY139353A (en) 2001-03-05 2009-09-30 Shell Int Research Process to prepare a lubricating base oil and a gas oil
MY137259A (en) 2001-03-05 2009-01-30 Shell Int Research Process to prepare a lubricating base oil and a gas oil.
JP2005507933A (ja) * 2001-10-29 2005-03-24 ザ ダウ ケミカル カンパニー 抗新生物性の樹枝状ポリマー薬物送達システム
ES2254973T3 (es) 2002-07-18 2006-06-16 Shell Internationale Research Maatschappij B.V. Procedimiento de preparacion de una cera microcristalina y de un combustible de destilado medio.
EP1525890A1 (en) * 2003-10-02 2005-04-27 Complex Biosystems GmbH Protein-Proteophore complexes
CA2629300C (en) 2005-11-17 2014-07-08 Zogenix, Inc. Delivery of viscous formulations by needle-free injection
HUP0700782A3 (en) * 2007-12-05 2009-11-30 Biostatin Gyogyszerkutato Fejl Novel peptides and amino acid derivatives, pharmaceutical compositions containing the same and use of the compounds
EP3000462A1 (en) 2008-04-28 2016-03-30 Zogenix, Inc. Novel formulations for treatment of migraine
NZ591052A (en) * 2008-08-05 2012-11-30 Univ Queensland Antigen-presenting scaffolds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995000540A1 (en) * 1993-06-18 1995-01-05 Robert Webber Synthetic carrier and immunogen
JP2001509796A (ja) * 1997-01-29 2001-07-24 ニユコメド・イメージング・アクシエセルカペト 重合体

Also Published As

Publication number Publication date
HUP0201975A3 (en) 2002-11-28
ZA200201089B (en) 2003-07-30
NO20020333L (no) 2002-01-22
AU6276600A (en) 2001-02-13
NO20020333D0 (no) 2002-01-22
ITFO990015A1 (it) 2001-01-23
PL353273A1 (en) 2003-11-03
HUP0201975A2 (en) 2002-10-28
EP1200461A2 (en) 2002-05-02
NZ517231A (en) 2003-05-30
AU772167B2 (en) 2004-04-08
JP2003506326A (ja) 2003-02-18
CN1364171A (zh) 2002-08-14
WO2001007469A3 (en) 2001-05-10
WO2001007469A2 (en) 2001-02-01

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Legal Events

Date Code Title Description
FZDE Discontinued