CA2379940A1 - Facteur cilaire neurotrophique modifie, son procede de production et ses procedes d'utilisation - Google Patents

Facteur cilaire neurotrophique modifie, son procede de production et ses procedes d'utilisation Download PDF

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Publication number
CA2379940A1
CA2379940A1 CA002379940A CA2379940A CA2379940A1 CA 2379940 A1 CA2379940 A1 CA 2379940A1 CA 002379940 A CA002379940 A CA 002379940A CA 2379940 A CA2379940 A CA 2379940A CA 2379940 A1 CA2379940 A1 CA 2379940A1
Authority
CA
Canada
Prior art keywords
leu
cntf
ala
glu
ser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002379940A
Other languages
English (en)
Inventor
Stanley J. Wiegand
Mark W. Sleeman
Philip D. Lambert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Regeneron Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/454,380 external-priority patent/US6680291B1/en
Application filed by Individual filed Critical Individual
Publication of CA2379940A1 publication Critical patent/CA2379940A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention a trait à l'utilisation du facteur ciliaire neutrotrophique modifié Ax-15 dans la fabrication d'un médicament utilisé dans une méthode de traitement du diabète, en particulier du diabète sucré non insulino-dépendant ou du diabète gestationnel.
CA002379940A 1999-08-13 2000-07-27 Facteur cilaire neurotrophique modifie, son procede de production et ses procedes d'utilisation Abandoned CA2379940A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US37383499A 1999-08-13 1999-08-13
US09/373,834 1999-08-13
US09/454,380 US6680291B1 (en) 1998-02-27 1999-12-03 Modified ciliary neurotrophic factor, method of making and methods of use thereof
US09/454,380 1999-12-03
PCT/US2000/020432 WO2001012810A1 (fr) 1999-08-13 2000-07-27 Facteur cilaire neurotrophique modifie, son procede de production et ses procedes d'utilisation

Publications (1)

Publication Number Publication Date
CA2379940A1 true CA2379940A1 (fr) 2001-02-22

Family

ID=27006327

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002379940A Abandoned CA2379940A1 (fr) 1999-08-13 2000-07-27 Facteur cilaire neurotrophique modifie, son procede de production et ses procedes d'utilisation

Country Status (10)

Country Link
EP (1) EP1200589A1 (fr)
JP (1) JP2003507393A (fr)
CN (1) CN1387568A (fr)
AU (1) AU6382200A (fr)
BR (1) BR0013204A (fr)
CA (1) CA2379940A1 (fr)
HU (1) HUP0203057A3 (fr)
IL (1) IL148033A0 (fr)
PL (1) PL364931A1 (fr)
WO (1) WO2001012810A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2439682A1 (fr) * 2001-03-02 2002-09-12 Merck Patent Gesellschaft Mit Beschrankter Haftung Facteur de croissance cntf a antigenicite reduite
CN100439396C (zh) * 2004-04-02 2008-12-03 西南生物工程产业化中试基地有限公司 人睫状神经营养因子的衍生物多肽及其制备方法和应用
CN100457778C (zh) * 2005-09-02 2009-02-04 中国药品生物制品检定所 睫状神经营养因子(cntf)突变体及其生产方法和其用途
CN101144082B (zh) * 2007-06-12 2012-09-05 兰州生物制品研究所有限责任公司 重组人睫状神经营养因子、突变体及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6472178B1 (en) * 1998-02-27 2002-10-29 Regeneron Pharmaceuticals, Inc. Nucleic acids encoding a modified ciliary neurotrophic factor and method of making thereof
US5349056A (en) * 1992-10-09 1994-09-20 Regeneron Pharmaceuticals Modified ciliary neurotrophic factors
AU718500B2 (en) * 1997-01-23 2000-04-13 Sumitomo Pharmaceuticals Company, Limited Remedies for diabetes

Also Published As

Publication number Publication date
CN1387568A (zh) 2002-12-25
BR0013204A (pt) 2004-02-17
PL364931A1 (en) 2004-12-27
IL148033A0 (en) 2002-09-12
EP1200589A1 (fr) 2002-05-02
WO2001012810A1 (fr) 2001-02-22
HUP0203057A3 (en) 2005-07-28
JP2003507393A (ja) 2003-02-25
HUP0203057A2 (hu) 2002-12-28
AU6382200A (en) 2001-03-13

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 20060727