PL364931A1 - Modified ciliary neurotrophic factor, method of making and methods of use thereof - Google Patents

Modified ciliary neurotrophic factor, method of making and methods of use thereof

Info

Publication number
PL364931A1
PL364931A1 PL00364931A PL36493100A PL364931A1 PL 364931 A1 PL364931 A1 PL 364931A1 PL 00364931 A PL00364931 A PL 00364931A PL 36493100 A PL36493100 A PL 36493100A PL 364931 A1 PL364931 A1 PL 364931A1
Authority
PL
Poland
Prior art keywords
making
methods
neurotrophic factor
ciliary neurotrophic
modified ciliary
Prior art date
Application number
PL00364931A
Other languages
Polish (pl)
Inventor
Stanley J. Wiegand
Mark W. Sleeman
Philip D. Lambert
Original Assignee
Regeneron Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/454,380 external-priority patent/US6680291B1/en
Application filed by Regeneron Pharmaceuticals, Inc. filed Critical Regeneron Pharmaceuticals, Inc.
Publication of PL364931A1 publication Critical patent/PL364931A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL00364931A 1999-08-13 2000-07-27 Modified ciliary neurotrophic factor, method of making and methods of use thereof PL364931A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37383499A 1999-08-13 1999-08-13
US09/454,380 US6680291B1 (en) 1998-02-27 1999-12-03 Modified ciliary neurotrophic factor, method of making and methods of use thereof

Publications (1)

Publication Number Publication Date
PL364931A1 true PL364931A1 (en) 2004-12-27

Family

ID=27006327

Family Applications (1)

Application Number Title Priority Date Filing Date
PL00364931A PL364931A1 (en) 1999-08-13 2000-07-27 Modified ciliary neurotrophic factor, method of making and methods of use thereof

Country Status (10)

Country Link
EP (1) EP1200589A1 (en)
JP (1) JP2003507393A (en)
CN (1) CN1387568A (en)
AU (1) AU6382200A (en)
BR (1) BR0013204A (en)
CA (1) CA2379940A1 (en)
HU (1) HUP0203057A3 (en)
IL (1) IL148033A0 (en)
PL (1) PL364931A1 (en)
WO (1) WO2001012810A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1379655A2 (en) * 2001-03-02 2004-01-14 MERCK PATENT GmbH Modified ciliary neurotrophic factor (cntf) with reduced immunogenicity
CN100439396C (en) * 2004-04-02 2008-12-03 西南生物工程产业化中试基地有限公司 Polypeptide of ramification of ciliary nerves nutrilite for curing obesity
CN100457778C (en) * 2005-09-02 2009-02-04 中国药品生物制品检定所 Mutant of ciliary nerves trophic factor (CNTF), producing method and usage
CN101144082B (en) * 2007-06-12 2012-09-05 兰州生物制品研究所有限责任公司 Recombination human ciliary neurotrophy factor, mutant and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5349056A (en) * 1992-10-09 1994-09-20 Regeneron Pharmaceuticals Modified ciliary neurotrophic factors
US6472178B1 (en) * 1998-02-27 2002-10-29 Regeneron Pharmaceuticals, Inc. Nucleic acids encoding a modified ciliary neurotrophic factor and method of making thereof
US6391312B1 (en) * 1997-01-23 2002-05-21 Sumitomo Pharmaceuticals Co., Limited Remedies for diabetes

Also Published As

Publication number Publication date
JP2003507393A (en) 2003-02-25
IL148033A0 (en) 2002-09-12
EP1200589A1 (en) 2002-05-02
HUP0203057A3 (en) 2005-07-28
CN1387568A (en) 2002-12-25
HUP0203057A2 (en) 2002-12-28
AU6382200A (en) 2001-03-13
BR0013204A (en) 2004-02-17
CA2379940A1 (en) 2001-02-22
WO2001012810A1 (en) 2001-02-22

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Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)