IL148033A0 - Modified ciliary neurotrophic factor, method of making and methods of use thereof - Google Patents

Modified ciliary neurotrophic factor, method of making and methods of use thereof

Info

Publication number
IL148033A0
IL148033A0 IL14803300A IL14803300A IL148033A0 IL 148033 A0 IL148033 A0 IL 148033A0 IL 14803300 A IL14803300 A IL 14803300A IL 14803300 A IL14803300 A IL 14803300A IL 148033 A0 IL148033 A0 IL 148033A0
Authority
IL
Israel
Prior art keywords
making
methods
neurotrophic factor
ciliary neurotrophic
modified ciliary
Prior art date
Application number
IL14803300A
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/454,380 external-priority patent/US6680291B1/en
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of IL148033A0 publication Critical patent/IL148033A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL14803300A 1999-08-13 2000-07-27 Modified ciliary neurotrophic factor, method of making and methods of use thereof IL148033A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37383499A 1999-08-13 1999-08-13
US09/454,380 US6680291B1 (en) 1998-02-27 1999-12-03 Modified ciliary neurotrophic factor, method of making and methods of use thereof
PCT/US2000/020432 WO2001012810A1 (en) 1999-08-13 2000-07-27 Modified ciliary neurotrophic factor, method of making and methods of use thereof

Publications (1)

Publication Number Publication Date
IL148033A0 true IL148033A0 (en) 2002-09-12

Family

ID=27006327

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14803300A IL148033A0 (en) 1999-08-13 2000-07-27 Modified ciliary neurotrophic factor, method of making and methods of use thereof

Country Status (10)

Country Link
EP (1) EP1200589A1 (en)
JP (1) JP2003507393A (en)
CN (1) CN1387568A (en)
AU (1) AU6382200A (en)
BR (1) BR0013204A (en)
CA (1) CA2379940A1 (en)
HU (1) HUP0203057A3 (en)
IL (1) IL148033A0 (en)
PL (1) PL364931A1 (en)
WO (1) WO2001012810A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030081480A (en) * 2001-03-02 2003-10-17 메르크 파텐트 게엠베하 Modified ciliary neurotrophic factor (cntf) with reduced immunogenicity
CN100439396C (en) * 2004-04-02 2008-12-03 西南生物工程产业化中试基地有限公司 Polypeptide of ramification of ciliary nerves nutrilite for curing obesity
CN100457778C (en) * 2005-09-02 2009-02-04 中国药品生物制品检定所 Mutant of ciliary nerves trophic factor (CNTF), producing method and usage
CN101144082B (en) * 2007-06-12 2012-09-05 兰州生物制品研究所有限责任公司 Recombination human ciliary neurotrophy factor, mutant and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5349056A (en) * 1992-10-09 1994-09-20 Regeneron Pharmaceuticals Modified ciliary neurotrophic factors
US6472178B1 (en) * 1998-02-27 2002-10-29 Regeneron Pharmaceuticals, Inc. Nucleic acids encoding a modified ciliary neurotrophic factor and method of making thereof
US6391312B1 (en) * 1997-01-23 2002-05-21 Sumitomo Pharmaceuticals Co., Limited Remedies for diabetes

Also Published As

Publication number Publication date
BR0013204A (en) 2004-02-17
EP1200589A1 (en) 2002-05-02
WO2001012810A1 (en) 2001-02-22
AU6382200A (en) 2001-03-13
PL364931A1 (en) 2004-12-27
JP2003507393A (en) 2003-02-25
CN1387568A (en) 2002-12-25
HUP0203057A3 (en) 2005-07-28
HUP0203057A2 (en) 2002-12-28
CA2379940A1 (en) 2001-02-22

Similar Documents

Publication Publication Date Title
IL149907A0 (en) Nutritional composition, methods of producing said composition and methods of using said composition
EP1148847A4 (en) Composite bone graft, method of making and using same
IL136951A0 (en) Sustained-release composition, method of its production and use thereof
GB2353139B (en) Inductor and method of manufacturing the same
HUP0200495A2 (en) Method of treating eating disorders
GB9929560D0 (en) Insert and method of manufacture thereof
EP1183030A4 (en) Methods of making and using n-desmethylzopiclone
CZ20012130A3 (en) Piperazine derivative, process of its preparation and use
EP1182451A4 (en) Biosensor and method of producing the same
EP1154452A4 (en) Relay and method of manufacture thereof
EP1367611A4 (en) Inductor part, and method of producing the same
HUP0400296A3 (en) Method for preparation of 10,11-dihydro-10-hydroxy-5h-dibenz/b,f/azepine-5-carboxamide and 10,11-dihydro-10-oxo-5h-dibenz/b,f/azepine-5-carboxamide
GB2343450B (en) Trimethylcyclohexenylcyclopropyl ketones, methods of their production and uses thereof
HK1040421A1 (en) Ornament and method for preparation thereof
HUP0203057A3 (en) Modified ciliary neurotrophic factor, method of making and methods of use thereof
HK1042901A1 (en) Substituted 3-pyridyl-4-arylpyrroles, and related therapeutic and prophylactic methods
PL342453A1 (en) Biphenylsulphonylcyanamides, method of obtaining them and their application as drugs
HUP0203468A3 (en) Betha-d-5-thioxylose derivatives, preparation method and therapeutic use thereof
HK1046018A1 (en) Modified ciliary neurotrophic factor, method of making and methods of use thereof
HUP0201400A3 (en) Method for producing 2,2,4,4-tetra-substituted 1,3,5-cyclohexanetriones and their new intermediates
PL333401A1 (en) Suspensions, method of obtaining them and their application
GB0006334D0 (en) Template and method of use thereof
GB2352450B (en) Method for producing of 2,3-dimethylbutene-1 and 2,3-dimethylbutene-2
IL140739A0 (en) Glyceryl trinitrate-containing preparation, method for its production, and its use
PL331788A1 (en) Novel 1,1-disubstituted-2-cyanocyclopropanes and method of obtaining them