HUP0203057A2 - Módosított ciliáris nerotróf faktor, ennek előállítási és használati módszere - Google Patents
Módosított ciliáris nerotróf faktor, ennek előállítási és használati módszereInfo
- Publication number
- HUP0203057A2 HUP0203057A2 HU0203057A HUP0203057A HUP0203057A2 HU P0203057 A2 HUP0203057 A2 HU P0203057A2 HU 0203057 A HU0203057 A HU 0203057A HU P0203057 A HUP0203057 A HU P0203057A HU P0203057 A2 HUP0203057 A2 HU P0203057A2
- Authority
- HU
- Hungary
- Prior art keywords
- neurotrophic factor
- making
- ciliary neurotrophic
- methods
- modified ciliary
- Prior art date
Links
- 108010005939 Ciliary Neurotrophic Factor Proteins 0.000 title abstract 2
- 102100031614 Ciliary neurotrophic factor Human genes 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000004104 gestational diabetes Diseases 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Emergency Medicine (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A találmány tárgya az Ax-15 módosított ciliáris neurotróf faktorhasználata olyan gyógyszer előállításában, amit diabetesz, főleg neminzulin dependens diabetesz mellitusz vagy terhességi diabeteszkezelési eljárásában használnak. Ó
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37383499A | 1999-08-13 | 1999-08-13 | |
US09/454,380 US6680291B1 (en) | 1998-02-27 | 1999-12-03 | Modified ciliary neurotrophic factor, method of making and methods of use thereof |
PCT/US2000/020432 WO2001012810A1 (en) | 1999-08-13 | 2000-07-27 | Modified ciliary neurotrophic factor, method of making and methods of use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0203057A2 true HUP0203057A2 (hu) | 2002-12-28 |
HUP0203057A3 HUP0203057A3 (en) | 2005-07-28 |
Family
ID=27006327
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0203057A HUP0203057A3 (en) | 1999-08-13 | 2000-07-27 | Modified ciliary neurotrophic factor, method of making and methods of use thereof |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1200589A1 (hu) |
JP (1) | JP2003507393A (hu) |
CN (1) | CN1387568A (hu) |
AU (1) | AU6382200A (hu) |
BR (1) | BR0013204A (hu) |
CA (1) | CA2379940A1 (hu) |
HU (1) | HUP0203057A3 (hu) |
IL (1) | IL148033A0 (hu) |
PL (1) | PL364931A1 (hu) |
WO (1) | WO2001012810A1 (hu) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1379655A2 (en) * | 2001-03-02 | 2004-01-14 | MERCK PATENT GmbH | Modified ciliary neurotrophic factor (cntf) with reduced immunogenicity |
CN100439396C (zh) * | 2004-04-02 | 2008-12-03 | 西南生物工程产业化中试基地有限公司 | 人睫状神经营养因子的衍生物多肽及其制备方法和应用 |
CN100457778C (zh) * | 2005-09-02 | 2009-02-04 | 中国药品生物制品检定所 | 睫状神经营养因子(cntf)突变体及其生产方法和其用途 |
CN101144082B (zh) * | 2007-06-12 | 2012-09-05 | 兰州生物制品研究所有限责任公司 | 重组人睫状神经营养因子、突变体及其应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5349056A (en) * | 1992-10-09 | 1994-09-20 | Regeneron Pharmaceuticals | Modified ciliary neurotrophic factors |
US6472178B1 (en) * | 1998-02-27 | 2002-10-29 | Regeneron Pharmaceuticals, Inc. | Nucleic acids encoding a modified ciliary neurotrophic factor and method of making thereof |
CN1250379A (zh) * | 1997-01-23 | 2000-04-12 | 住友制药株式会社 | 糖尿病治疗剂 |
-
2000
- 2000-07-27 IL IL14803300A patent/IL148033A0/xx unknown
- 2000-07-27 EP EP00950767A patent/EP1200589A1/en not_active Withdrawn
- 2000-07-27 CA CA002379940A patent/CA2379940A1/en not_active Abandoned
- 2000-07-27 HU HU0203057A patent/HUP0203057A3/hu unknown
- 2000-07-27 AU AU63822/00A patent/AU6382200A/en not_active Abandoned
- 2000-07-27 BR BR0013204-7A patent/BR0013204A/pt not_active Application Discontinuation
- 2000-07-27 WO PCT/US2000/020432 patent/WO2001012810A1/en not_active Application Discontinuation
- 2000-07-27 PL PL00364931A patent/PL364931A1/xx not_active Application Discontinuation
- 2000-07-27 JP JP2001517694A patent/JP2003507393A/ja not_active Withdrawn
- 2000-07-27 CN CN00814294A patent/CN1387568A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
BR0013204A (pt) | 2004-02-17 |
CN1387568A (zh) | 2002-12-25 |
WO2001012810A1 (en) | 2001-02-22 |
CA2379940A1 (en) | 2001-02-22 |
IL148033A0 (en) | 2002-09-12 |
PL364931A1 (en) | 2004-12-27 |
JP2003507393A (ja) | 2003-02-25 |
HUP0203057A3 (en) | 2005-07-28 |
AU6382200A (en) | 2001-03-13 |
EP1200589A1 (en) | 2002-05-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA9A | Lapse of provisional patent protection due to relinquishment or protection considered relinquished |