CA2372051A1 - Composes heterocycliques a contenu imidazo, preparations en etant faites, et leurs utilisations - Google Patents

Composes heterocycliques a contenu imidazo, preparations en etant faites, et leurs utilisations Download PDF

Info

Publication number
CA2372051A1
CA2372051A1 CA002372051A CA2372051A CA2372051A1 CA 2372051 A1 CA2372051 A1 CA 2372051A1 CA 002372051 A CA002372051 A CA 002372051A CA 2372051 A CA2372051 A CA 2372051A CA 2372051 A1 CA2372051 A1 CA 2372051A1
Authority
CA
Canada
Prior art keywords
hydrogen
alkyl
aryl
group
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002372051A
Other languages
English (en)
Inventor
Song Liu
David Edward Portlock
Schwe Fang Pong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2372051A1 publication Critical patent/CA2372051A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

L'invention porte sur des composés de structure (I) dans laquelle R1 est indépendamment alkyle, aryle, ou hétérocycle; chaque R2 - R7 est indépendamment H ou un autre substituant; B est nul et n est 0-3, ou B est éthényle et n est 0-1; et sur leurs formes pharmacocompatibles. L'invention porte également sur des préparations pharmaceutiques contenant lesdits composés et sur des procédés de traitement ou de prévention de maladies ou de troubles à l'aide desdits composés.
CA002372051A 1999-05-19 2000-05-16 Composes heterocycliques a contenu imidazo, preparations en etant faites, et leurs utilisations Abandoned CA2372051A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13482299P 1999-05-19 1999-05-19
US60/134,822 1999-05-19
PCT/US2000/013413 WO2000069860A1 (fr) 1999-05-19 2000-05-16 Composes heterocycliques a contenu imidazo, preparations en etant faites, et leurs utilisations

Publications (1)

Publication Number Publication Date
CA2372051A1 true CA2372051A1 (fr) 2000-11-23

Family

ID=22465179

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002372051A Abandoned CA2372051A1 (fr) 1999-05-19 2000-05-16 Composes heterocycliques a contenu imidazo, preparations en etant faites, et leurs utilisations

Country Status (13)

Country Link
EP (1) EP1183258A1 (fr)
JP (1) JP2002544279A (fr)
KR (1) KR20020002462A (fr)
CN (1) CN1350539A (fr)
AU (1) AU755088B2 (fr)
BR (1) BR0010748A (fr)
CA (1) CA2372051A1 (fr)
CZ (1) CZ20014099A3 (fr)
HU (1) HUP0201308A3 (fr)
IL (1) IL146305A0 (fr)
MX (1) MXPA01011860A (fr)
NO (1) NO20015564L (fr)
WO (1) WO2000069860A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1411449A (zh) * 1999-12-17 2003-04-16 宝洁公司 N－(1－苯乙基)－5－苯基－咪唑－2－胺化合物,它们的组合物和应用
US6596739B2 (en) 2000-03-29 2003-07-22 The Procter & Gamble Company N-(1-phenylethyl)-5-phenyl-imidazole-2-amine compounds, their compositions and uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU167240B (fr) * 1972-06-30 1975-09-27
CH603643A5 (fr) * 1976-09-29 1978-08-31 Sandoz Ag
JPH08291173A (ja) * 1995-04-17 1996-11-05 Lederle Japan Ltd イミダゾキノリン類縁体
US6476020B1 (en) * 1998-10-14 2002-11-05 The Procter & Gamble Company Imidazo-benzazepine compounds, their compositions and uses
WO2000021961A1 (fr) * 1998-10-14 2000-04-20 The Procter & Gamble Company Composes d'imidazo-isoquinoline, leurs compositions et leurs utilisations

Also Published As

Publication number Publication date
NO20015564D0 (no) 2001-11-14
JP2002544279A (ja) 2002-12-24
HUP0201308A3 (en) 2003-07-28
IL146305A0 (en) 2002-07-25
HUP0201308A2 (en) 2002-08-28
EP1183258A1 (fr) 2002-03-06
CN1350539A (zh) 2002-05-22
WO2000069860A1 (fr) 2000-11-23
CZ20014099A3 (cs) 2002-04-17
AU5019500A (en) 2000-12-05
AU755088B2 (en) 2002-12-05
KR20020002462A (ko) 2002-01-09
MXPA01011860A (es) 2002-05-06
NO20015564L (no) 2001-11-14
BR0010748A (pt) 2002-02-19

Similar Documents

Publication Publication Date Title
KR20190038485A (ko) Fgfr4 저해제인 헤테로 고리 화합물
EP0799827A1 (fr) Derives d'acrylamide et leur procede de production
US5258383A (en) DC-89 derivatives
JP3853389B2 (ja) 新規の３−フェニルスルホニル−３，７−ジアザビシクロ［３，３，１］ノナン−化合物、その製法及び抗不整脈剤
AU755088B2 (en) Imidazo-containing heterocyclic compounds, their compositions and uses
US5214065A (en) Dc-89 derivatives
US20030100593A1 (en) N-(1-phenylethyl)-5-phenyl-imidazole-2-amine compounds, their compositions and uses
US6552033B1 (en) Imidazo-containing heterocyclic compounds, their compositions and uses
US6476020B1 (en) Imidazo-benzazepine compounds, their compositions and uses
US6159985A (en) Imidazo-isoquinoline compounds, their compositions and uses
CA2394570A1 (fr) Composes de n-(1-phenylethyl)-5-phenyl-imidazole-2-amine, leurs compositions et utilisations
AU748699B2 (en) Imidazo-isoquinoline compounds, their compositions and uses
CN113698415A (zh) 一种新型的冬凌草甲素类似物及衍生物、其制备方法及医药用途
WO2019184919A1 (fr) Composé contenant de l'adamantane et son utilisation dans le traitement du cancer
EA007222B1 (ru) Способ получения кислотных солей гемифлоксацина
US5248692A (en) DC-89 derivatives as anti-tumor agents
CN115536699B (zh) 一种新型EGFR-TKIs、制备方法、药物组合物及其应用
JPH05178858A (ja) Ｄｃ−８９誘導体
CZ286654B6 (cs) 2-/2-/(2-hydroxyethyl) amino/ethyl/-5-//(2-methylamino)ethyl/amino/indazol/4,3-gh/isochinolin-6(2H) on, způsob jeho výroby a farmaceutický prostředek s jeho obsahem
CN117777093A (zh) 一种用于制备GnRH1R激动剂的小分子化合物
KR19980076903A (ko) 신규한 퀴놀론카르복실산 유도체
WO1993018771A1 (fr) INHIBITEUR DE L'AGGLUTINATION PLAQUETTAIRE CONTENANT UN DERIVE DE STAUROSPORINE η-LACTAME

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued