CA2371828A1 - Acides nucleiques isoles de la famille p-hyde, proteines p-hyde et procede pour induire la susceptibilite a l'induction de la mort cellulaire programmee pendant le cancer - Google Patents

Acides nucleiques isoles de la famille p-hyde, proteines p-hyde et procede pour induire la susceptibilite a l'induction de la mort cellulaire programmee pendant le cancer Download PDF

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Publication number
CA2371828A1
CA2371828A1 CA002371828A CA2371828A CA2371828A1 CA 2371828 A1 CA2371828 A1 CA 2371828A1 CA 002371828 A CA002371828 A CA 002371828A CA 2371828 A CA2371828 A CA 2371828A CA 2371828 A1 CA2371828 A1 CA 2371828A1
Authority
CA
Canada
Prior art keywords
hyde
nucleic acid
cells
protein
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002371828A
Other languages
English (en)
Inventor
Mitchell S. Steiner
Chiang Wang
Augustinus Rinaldy
Rema Menon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Tennessee Research Foundation
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/499,817 external-priority patent/US7043009B1/en
Application filed by Individual filed Critical Individual
Publication of CA2371828A1 publication Critical patent/CA2371828A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Abstract

L'invention concerne des acides nucléiques isolés de la famille p-Hyde, des analogues, des fragments, des mutants et des variants de la famille p-Hyde. L'invention couvre des polypeptides, des protéines de fusion, des chimères, des molécules antisens, des anticorps et des procédés d'utilisation correspondants. Elle concerne aussi un procédé pour induire la susceptibilité à l'apoptose au moyen de p-Hyde, un procédé pour bloquer la croissance d'une tumeur au moyen de p-Hyde et un procédé pour traiter un sujet souffrant du cancer au moyen de p-Hyde pris isolément ou en combinaison avec une chimiothérapie, un traitement par rayonnements ou traitement par des médicaments imitant les ultraviolets. L'invention concerne aussi le traitement des cancers chez l'homme accompagnés d'une mutation dans le gène p-Hyde, y compris la thérapie génique, la thérapie par remplacement de protéines et par mimétisme de protéines. L'invention concerne en outre le criblage de médicaments à la recherche d'une thérapie du cancer. Elle concerne enfin le criblage du gène p-Hyde à la recherche des mutations utiles pour diagnostiquer la prédisposition au cancer.
CA002371828A 1999-04-29 2000-05-01 Acides nucleiques isoles de la famille p-hyde, proteines p-hyde et procede pour induire la susceptibilite a l'induction de la mort cellulaire programmee pendant le cancer Abandoned CA2371828A1 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US13160799P 1999-04-29 1999-04-29
US30245799A 1999-04-29 1999-04-29
US60/131,607 1999-04-29
US09/302,457 1999-04-29
US09/499,817 2000-02-08
US09/499,817 US7043009B1 (en) 2000-02-08 2000-02-08 Providing customer data to an automatic call distribution system agent
PCT/US2000/011456 WO2000071564A2 (fr) 1999-04-29 2000-05-01 Acides nucleiques isoles de la famille p-hyde, proteines p-hyde et procede pour induire la susceptibilite a l'induction de la mort cellulaire programmee pendant le cancer

Publications (1)

Publication Number Publication Date
CA2371828A1 true CA2371828A1 (fr) 2000-11-30

Family

ID=27384176

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002371828A Abandoned CA2371828A1 (fr) 1999-04-29 2000-05-01 Acides nucleiques isoles de la famille p-hyde, proteines p-hyde et procede pour induire la susceptibilite a l'induction de la mort cellulaire programmee pendant le cancer

Country Status (5)

Country Link
EP (1) EP1328151A4 (fr)
JP (1) JP2003529321A (fr)
AU (1) AU769889B2 (fr)
CA (1) CA2371828A1 (fr)
WO (1) WO2000071564A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6835812B1 (en) 1999-04-29 2004-12-28 University Of Tennessee Research Corporation Human p-Hyde proteins
CN113106082B (zh) * 2021-05-27 2022-11-04 云南师范大学 动物粪便宏基因组来源的丙氨酸消旋酶及其制备和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69635349T2 (de) * 1995-12-20 2006-07-20 Cerenis Nukleotidsequenzen, proteine, medikamente und diagnoseagentien zur anwendung in krebsbehandlung
EP1074617A3 (fr) * 1999-07-29 2004-04-21 Research Association for Biotechnology Amorces pour la synthèse de cADN de pleine longueur et leur utilisation
EP1254236A2 (fr) * 2000-02-11 2002-11-06 Incyte Genomics, Inc. Enzymes metabolisant les medicaments
EP1268526A4 (fr) * 2000-03-24 2004-09-08 Fahri Saatcioglu Molecules d'acide nucleique specifiques de la prostate ou des testicules, polypeptides, techniques de diagnostic, et traitement therapeutique

Also Published As

Publication number Publication date
AU6604600A (en) 2000-12-12
JP2003529321A (ja) 2003-10-07
WO2000071564A2 (fr) 2000-11-30
WO2000071564A8 (fr) 2001-10-04
AU769889B2 (en) 2004-02-05
WO2000071564A3 (fr) 2003-05-01
EP1328151A2 (fr) 2003-07-23
EP1328151A4 (fr) 2004-06-16

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead