CA2366706A1 - Mammalian cytokines; related reagents and methods - Google Patents

Mammalian cytokines; related reagents and methods Download PDF

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Publication number
CA2366706A1
CA2366706A1 CA002366706A CA2366706A CA2366706A1 CA 2366706 A1 CA2366706 A1 CA 2366706A1 CA 002366706 A CA002366706 A CA 002366706A CA 2366706 A CA2366706 A CA 2366706A CA 2366706 A1 CA2366706 A1 CA 2366706A1
Authority
CA
Canada
Prior art keywords
polypeptide
amino acids
seq
mature
complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002366706A
Other languages
English (en)
French (fr)
Inventor
Birgit Oppmann
Jacqueline C. Timans
Robert A. Kastelein
J. Fernando Bazan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2366706A1 publication Critical patent/CA2366706A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002366706A 1999-03-11 2000-03-09 Mammalian cytokines; related reagents and methods Abandoned CA2366706A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26790199A 1999-03-11 1999-03-11
US09/267,901 1999-03-11
PCT/US2000/006182 WO2000053631A1 (en) 1999-03-11 2000-03-09 Mammalian cytokines; related reagents and methods

Publications (1)

Publication Number Publication Date
CA2366706A1 true CA2366706A1 (en) 2000-09-14

Family

ID=23020618

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002366706A Abandoned CA2366706A1 (en) 1999-03-11 2000-03-09 Mammalian cytokines; related reagents and methods

Country Status (9)

Country Link
EP (2) EP1159299B1 (enExample)
JP (1) JP2003500010A (enExample)
AR (1) AR022890A1 (enExample)
AT (1) ATE420894T1 (enExample)
AU (1) AU3873200A (enExample)
CA (1) CA2366706A1 (enExample)
DE (1) DE60041393D1 (enExample)
ES (1) ES2319958T3 (enExample)
WO (1) WO2000053631A1 (enExample)

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FR2804435A1 (fr) * 2000-01-27 2001-08-03 Pf Medicament COMPLEXE ISOLE COMPRENANT UNE PROTEINE NNT-1 ET EN OUTRE AU MOINS UNE PROTEINE CLF-1 ET/OU UNE PROTEINE sCNTFRalpha
US7045283B2 (en) * 2000-10-18 2006-05-16 The Regents Of The University Of California Methods of high-throughput screening for internalizing antibodies
US7247711B2 (en) 2003-05-09 2007-07-24 Centocor, Inc. IL-23p40 specific antibody
AR051444A1 (es) 2004-09-24 2007-01-17 Centocor Inc Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos
PL1896073T3 (pl) 2005-06-30 2013-08-30 Janssen Biotech Inc Przeciwciała anty-IL-23, kompozycje, sposoby i zastosowania
HRP20170444T1 (hr) 2005-08-31 2017-05-19 Merck Sharp & Dohme Corp. Projektirana anti-il-23 antitijela
DK3219328T3 (da) 2005-12-29 2020-07-13 Janssen Biotech Inc Humane anti-il-23-antistoffer, sammensætninger, fremgangsmåder og anvendelser
MX2009009079A (es) 2007-02-23 2009-08-31 Schering Corp Anticuerpos anti-il-23p19 de ingenieria.
EP2064242A1 (en) 2007-02-23 2009-06-03 Schering Corporation Engineered anti-il-23p19 antibodies
BRPI0807991A2 (pt) 2007-02-28 2014-06-17 Schering Corp Anticorpos anti-il-23r elaborados.
EP2417974A1 (en) 2007-02-28 2012-02-15 Schering Corporation Combination therapy for treatment of immune disorders
US9803010B2 (en) 2012-06-27 2017-10-31 Merck Sharp & Dohme Corp. Crystalline anti-human IL-23p19 antibodies
UA117466C2 (uk) 2012-12-13 2018-08-10 Мерк Шарп Енд Доме Корп. СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
JOP20190260A1 (ar) 2017-05-02 2019-10-31 Merck Sharp & Dohme صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
JP7382232B2 (ja) 2017-05-02 2023-11-16 メルク・シャープ・アンド・ドーム・エルエルシー 抗ｌａｇ３抗体の製剤および抗ｌａｇ３抗体と抗ｐｄ－１抗体との共製剤
MX2021005394A (es) 2018-11-07 2021-07-06 Merck Sharp & Dohme Llc Co-formulaciones de anticuerpos anti-gen de activacion de linfocitos 3 (anti-lag3) y anticuerpos anti-muerte programada-1 (anti-pd-1).
US11548941B2 (en) 2018-11-20 2023-01-10 Janssen Biotech, Inc. Safe and effective method of treating psoriasis with anti-IL-23 specific antibody
JP2022534020A (ja) 2019-05-23 2022-07-27 ヤンセン バイオテツク，インコーポレーテツド Ｉｌ－２３及びｔｎｆアルファに対する抗体の併用療法による炎症性腸疾患の治療方法
KR20230023663A (ko) 2020-05-21 2023-02-17 얀센 바이오테크 인코포레이티드 Il-23 및 tnf 알파에 대한 항체의 병용 요법으로 염증성 장질환을 치료하는 방법

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US3940475A (en) 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
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US4859609A (en) 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
US5470952A (en) * 1993-10-20 1995-11-28 Regeneron Pharmaceuticals, Inc. CNTF and IL-6 antagonists
ES2255067T3 (es) * 1995-08-01 2006-06-16 F. Hoffmann-La Roche Ag Receptores para la interleucina-12 humana.
AUPO224696A0 (en) * 1996-09-11 1996-10-03 Amrad Operations Pty. Limited A novel haemopoietin receptor and genetic sequences encoding same
EP1005552A1 (en) * 1997-01-16 2000-06-07 Genetics Institute, Inc. Member of the hematopoietin receptor superfamily
US5741772A (en) * 1997-02-03 1998-04-21 Amgen Inc. Neurotrophic factor NNT-1
JP2002514067A (ja) * 1997-02-03 2002-05-14 アムジエン・インコーポレーテツド 神経栄養因子ｎｎｔ−１
WO1998049307A1 (en) * 1997-05-01 1998-11-05 Zymogenetics, Inc. Mammalian cytokine-like receptor
US6046035A (en) * 1997-06-30 2000-04-04 Human Genome Sciences, Inc. Polynucleotides encoding a cardiotrophin-like cytokine
GB9721961D0 (en) * 1997-10-16 1997-12-17 Glaxo Group Ltd Novel molecules
KR100386046B1 (ko) * 1997-12-03 2003-06-02 제넨테크, 인크. 폴리펩티드 및 이를 암호화하는 핵산
WO1999035264A1 (en) * 1998-01-09 1999-07-15 Immunex Corporation H14 dna and polypeptides
AU2661199A (en) * 1998-02-06 1999-08-23 Schering Corporation Mammalian receptor proteins; related reagents and methods
PT1181366E (pt) * 1999-06-01 2009-05-25 Schering Corp Proteínas receptoras de mamífero; reagentes e métodos relacionados
FR2804435A1 (fr) * 2000-01-27 2001-08-03 Pf Medicament COMPLEXE ISOLE COMPRENANT UNE PROTEINE NNT-1 ET EN OUTRE AU MOINS UNE PROTEINE CLF-1 ET/OU UNE PROTEINE sCNTFRalpha

Also Published As

Publication number Publication date
AR022890A1 (es) 2002-09-04
WO2000053631A1 (en) 2000-09-14
EP1159299A1 (en) 2001-12-05
EP1942114A2 (en) 2008-07-09
ATE420894T1 (de) 2009-01-15
EP1942114A3 (en) 2008-08-27
AU3873200A (en) 2000-09-28
ES2319958T3 (es) 2009-05-18
JP2003500010A (ja) 2003-01-07
DE60041393D1 (de) 2009-03-05
EP1159299B1 (en) 2009-01-14

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued