JP2003500010A - 哺乳動物サイトカイン；関連試薬および方法 - Google Patents

哺乳動物サイトカイン；関連試薬および方法

Info

Publication number
JP2003500010A
JP2003500010A JP2000604066A JP2000604066A JP2003500010A JP 2003500010 A JP2003500010 A JP 2003500010A JP 2000604066 A JP2000604066 A JP 2000604066A JP 2000604066 A JP2000604066 A JP 2000604066A JP 2003500010 A JP2003500010 A JP 2003500010A
Authority
JP
Japan
Prior art keywords
amino acids
polypeptide
seq
segment
mature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000604066A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003500010A5 (enExample
Inventor
ビルギット・オップマン
ジャクリーン・シー・ティマンズ
ロバート・エイ・カステライン
ジェイ・フェルナンド・バザン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of JP2003500010A publication Critical patent/JP2003500010A/ja
Publication of JP2003500010A5 publication Critical patent/JP2003500010A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2000604066A 1999-03-11 2000-03-09 哺乳動物サイトカイン；関連試薬および方法 Pending JP2003500010A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26790199A 1999-03-11 1999-03-11
US09/267,901 1999-03-11
PCT/US2000/006182 WO2000053631A1 (en) 1999-03-11 2000-03-09 Mammalian cytokines; related reagents and methods

Publications (2)

Publication Number Publication Date
JP2003500010A true JP2003500010A (ja) 2003-01-07
JP2003500010A5 JP2003500010A5 (enExample) 2007-05-10

Family

ID=23020618

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000604066A Pending JP2003500010A (ja) 1999-03-11 2000-03-09 哺乳動物サイトカイン；関連試薬および方法

Country Status (9)

Country Link
EP (2) EP1159299B1 (enExample)
JP (1) JP2003500010A (enExample)
AR (1) AR022890A1 (enExample)
AT (1) ATE420894T1 (enExample)
AU (1) AU3873200A (enExample)
CA (1) CA2366706A1 (enExample)
DE (1) DE60041393D1 (enExample)
ES (1) ES2319958T3 (enExample)
WO (1) WO2000053631A1 (enExample)

Families Citing this family (19)

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FR2804435A1 (fr) * 2000-01-27 2001-08-03 Pf Medicament COMPLEXE ISOLE COMPRENANT UNE PROTEINE NNT-1 ET EN OUTRE AU MOINS UNE PROTEINE CLF-1 ET/OU UNE PROTEINE sCNTFRalpha
US7045283B2 (en) * 2000-10-18 2006-05-16 The Regents Of The University Of California Methods of high-throughput screening for internalizing antibodies
JP2007515939A (ja) 2003-05-09 2007-06-21 セントカー・インコーポレーテツド ＩＬ−２３ｐ４０特異的免疫グロブリン由来タンパク質、組成物、方法および用途
AR051444A1 (es) 2004-09-24 2007-01-17 Centocor Inc Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos
ES2410406T3 (es) 2005-06-30 2013-07-01 Janssen Biotech, Inc. Anticuerpos anti-IL-23, composiciones, procedimientos y usos
HUE032131T2 (en) 2005-08-31 2017-09-28 Merck Sharp & Dohme Constructed anti-IL-23 antibodies
EP3219328B1 (en) 2005-12-29 2020-06-17 Janssen Biotech, Inc. Human anti-il-23 antibodies, compositions, method and uses
EP2064242A1 (en) 2007-02-23 2009-06-03 Schering Corporation Engineered anti-il-23p19 antibodies
ATE554791T1 (de) 2007-02-23 2012-05-15 Schering Corp Gentechnisch hergestellte anti-il-23p19- antikörper
CA2679381A1 (en) 2007-02-28 2008-09-04 Schering Corporation Engineered anti-il-23r antibodies
AU2008219681A1 (en) 2007-02-28 2008-09-04 Merck Sharp & Dohme Corp. Combination therapy for treatment of immune disorders
WO2014004436A2 (en) 2012-06-27 2014-01-03 Merck Sharp & Dohme Corp. Crystalline anti-human il-23 antibodies
UA117466C2 (uk) 2012-12-13 2018-08-10 Мерк Шарп Енд Доме Корп. СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
JOP20190260A1 (ar) 2017-05-02 2019-10-31 Merck Sharp & Dohme صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
WO2018204374A1 (en) 2017-05-02 2018-11-08 Merck Sharp & Dohme Corp. Formulations of anti-lag3 antibodies and co-formulations of anti-lag3 antibodies and anti-pd-1 antibodies
KR20210089215A (ko) 2018-11-07 2021-07-15 머크 샤프 앤드 돔 코포레이션 항-lag3 항체 및 항-pd-1 항체의 공동-제제
AU2019383017A1 (en) 2018-11-20 2021-06-03 Janssen Biotech, Inc. Safe and effective method of treating psoriasis with anti-IL-23 specific antibody
KR20220012883A (ko) 2019-05-23 2022-02-04 얀센 바이오테크 인코포레이티드 Il-23 및 tnf 알파에 대한 항체의 병용요법으로 염증성 장질환을 치료하는 방법
BR112022023489A2 (pt) 2020-05-21 2023-03-14 Janssen Biotech Inc Método de tratamento de doença inflamatória intestinal com uma terapia de combinação de anticorpos para il-23 e tnf-alfa

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998033922A1 (en) * 1997-02-03 1998-08-06 Amgen Inc. The neurotrophic factor nnt-1
WO1999000415A1 (en) * 1997-06-30 1999-01-07 Human Genome Sciences, Inc. Cardiotrophin-like cytokine
JP2001503612A (ja) * 1996-09-11 2001-03-21 アムラド・オペレイションズ・プロプライエタリー・リミテッド 新規ヘモポイエチン受容体およびこれをコードする遺伝子配列

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Publication number Priority date Publication date Assignee Title
US3940475A (en) 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
EP0088994B1 (en) 1982-03-15 1991-06-19 Schering Corporation Hybrid dna, binding composition prepared thereby and processes therefor
US4659678A (en) 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4859609A (en) 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
US5470952A (en) * 1993-10-20 1995-11-28 Regeneron Pharmaceuticals, Inc. CNTF and IL-6 antagonists
DK1243597T3 (da) * 1995-08-01 2008-09-22 Hoffmann La Roche Receptorer for det humane interleukin-12
EP1005552A1 (en) * 1997-01-16 2000-06-07 Genetics Institute, Inc. Member of the hematopoietin receptor superfamily
US5741772A (en) * 1997-02-03 1998-04-21 Amgen Inc. Neurotrophic factor NNT-1
AU7276098A (en) * 1997-05-01 1998-11-24 Zymogenetics Inc. Mammalian cytokine-like receptor
GB9721961D0 (en) * 1997-10-16 1997-12-17 Glaxo Group Ltd Novel molecules
AU736506B2 (en) * 1997-12-03 2001-07-26 Genentech Inc. Polypeptides and nucleic acids encoding the same
AU2454399A (en) * 1998-01-09 1999-07-26 Immunex Corporation H14 dna and polypeptides
AU2661199A (en) * 1998-02-06 1999-08-23 Schering Corporation Mammalian receptor proteins; related reagents and methods
WO2000073451A1 (en) * 1999-06-01 2000-12-07 Schering Corporation Mammalian receptor proteins; related reagents and methods
FR2804435A1 (fr) * 2000-01-27 2001-08-03 Pf Medicament COMPLEXE ISOLE COMPRENANT UNE PROTEINE NNT-1 ET EN OUTRE AU MOINS UNE PROTEINE CLF-1 ET/OU UNE PROTEINE sCNTFRalpha

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001503612A (ja) * 1996-09-11 2001-03-21 アムラド・オペレイションズ・プロプライエタリー・リミテッド 新規ヘモポイエチン受容体およびこれをコードする遺伝子配列
WO1998033922A1 (en) * 1997-02-03 1998-08-06 Amgen Inc. The neurotrophic factor nnt-1
WO1999000415A1 (en) * 1997-06-30 1999-01-07 Human Genome Sciences, Inc. Cardiotrophin-like cytokine

Also Published As

Publication number Publication date
AU3873200A (en) 2000-09-28
CA2366706A1 (en) 2000-09-14
ATE420894T1 (de) 2009-01-15
EP1159299A1 (en) 2001-12-05
ES2319958T3 (es) 2009-05-18
EP1942114A3 (en) 2008-08-27
AR022890A1 (es) 2002-09-04
EP1942114A2 (en) 2008-07-09
WO2000053631A1 (en) 2000-09-14
EP1159299B1 (en) 2009-01-14
DE60041393D1 (de) 2009-03-05

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