CA2358967A1 - Hesperitin pro-forms with enhanced bioavailability - Google Patents
Hesperitin pro-forms with enhanced bioavailability Download PDFInfo
- Publication number
- CA2358967A1 CA2358967A1 CA002358967A CA2358967A CA2358967A1 CA 2358967 A1 CA2358967 A1 CA 2358967A1 CA 002358967 A CA002358967 A CA 002358967A CA 2358967 A CA2358967 A CA 2358967A CA 2358967 A1 CA2358967 A1 CA 2358967A1
- Authority
- CA
- Canada
- Prior art keywords
- acid salt
- pro
- moiety
- hesperetin
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/32—2,3-Dihydro derivatives, e.g. flavanones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11756799P | 1999-01-27 | 1999-01-27 | |
US11819899P | 1999-02-01 | 1999-02-01 | |
US60/117,567 | 1999-02-01 | ||
US60/118,198 | 1999-02-01 | ||
PCT/US2000/001923 WO2000044757A1 (en) | 1999-01-27 | 2000-01-26 | Hesperitin pro-forms with enhanced bioavailability |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2358967A1 true CA2358967A1 (en) | 2000-08-03 |
Family
ID=26815410
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002358967A Abandoned CA2358967A1 (en) | 1999-01-27 | 2000-01-26 | Hesperitin pro-forms with enhanced bioavailability |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1155021A1 (ja) |
JP (1) | JP2002535410A (ja) |
CN (1) | CN1337966A (ja) |
AU (1) | AU764186B2 (ja) |
CA (1) | CA2358967A1 (ja) |
WO (1) | WO2000044757A1 (ja) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4522625B2 (ja) * | 2001-09-27 | 2010-08-11 | 株式会社ポッカコーポレーション | 柑橘属発酵物及びその製造方法 |
JP4522624B2 (ja) * | 2001-09-27 | 2010-08-11 | 株式会社ポッカコーポレーション | レモン発酵物及びその製造方法 |
CA2601028C (en) | 2005-03-11 | 2014-05-27 | Howard Florey Institute Of Experimental Physiology And Medecine | Flavonoid compounds and uses thereof |
AU2008282261A1 (en) | 2007-07-31 | 2009-02-05 | Limerick Biopharma, Inc. | Phosphorylated pyrone analogs and methods |
CN102746264A (zh) * | 2012-08-06 | 2012-10-24 | 西南大学 | 7-苯甲氧基橙皮素及其制备方法和用途 |
CN106565657A (zh) * | 2016-11-23 | 2017-04-19 | 陕西科技大学 | 一种具抗肿瘤活性的橙皮素肉桂酸酯类化合物及其合成方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0695181A1 (en) * | 1993-04-20 | 1996-02-07 | The Procter & Gamble Company | Methods of using hesperetin for sebum control and treatment of acne |
KR100213895B1 (ko) * | 1996-10-14 | 1999-08-02 | 박원훈 | 감귤류 과피 추출물, 이로부터 분리 정제된 헤스페리딘 또는 나린진을 포함하는 심혈관 질환 예방및 치료제 조성물 |
-
2000
- 2000-01-26 WO PCT/US2000/001923 patent/WO2000044757A1/en active Search and Examination
- 2000-01-26 JP JP2000596013A patent/JP2002535410A/ja active Pending
- 2000-01-26 CA CA002358967A patent/CA2358967A1/en not_active Abandoned
- 2000-01-26 EP EP00904573A patent/EP1155021A1/en not_active Withdrawn
- 2000-01-26 AU AU26309/00A patent/AU764186B2/en not_active Ceased
- 2000-01-26 CN CN00803072A patent/CN1337966A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2630900A (en) | 2000-08-18 |
CN1337966A (zh) | 2002-02-27 |
AU764186B2 (en) | 2003-08-14 |
WO2000044757A1 (en) | 2000-08-03 |
EP1155021A1 (en) | 2001-11-21 |
JP2002535410A (ja) | 2002-10-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |