CA2348514A1 - Transplantation intra-uterine de cellules embryonnaires mesenchymateuses humaines - Google Patents

Transplantation intra-uterine de cellules embryonnaires mesenchymateuses humaines Download PDF

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Publication number
CA2348514A1
CA2348514A1 CA002348514A CA2348514A CA2348514A1 CA 2348514 A1 CA2348514 A1 CA 2348514A1 CA 002348514 A CA002348514 A CA 002348514A CA 2348514 A CA2348514 A CA 2348514A CA 2348514 A1 CA2348514 A1 CA 2348514A1
Authority
CA
Canada
Prior art keywords
human
cells
mesenchymal stem
stem cells
organ
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002348514A
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English (en)
Inventor
Mark Thiede
Alan Flake
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Osiris Therapeutics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2348514A1 publication Critical patent/CA2348514A1/fr
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention se rapporte à des cellules embryonnaires mésenchymateuses destinées à une transplantation intra-utérine. Ces cellules embryonnaires mésenchymateuses peuvent être utilisées dans une méthode de traitement d'un foetus, ou dans une méthode de greffe de cellules embryonnaires mésenchymateuses, ou encore dans une méthode de préparation d'un organe en vue de sa transplantation.
CA002348514A 1998-11-13 1999-11-12 Transplantation intra-uterine de cellules embryonnaires mesenchymateuses humaines Abandoned CA2348514A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10835798P 1998-11-13 1998-11-13
US60/108,357 1998-11-13
PCT/US1999/026927 WO2000029002A2 (fr) 1998-11-13 1999-11-12 Transplantation intra-uterine de cellules embryonnaires mesenchymateuses humaines

Publications (1)

Publication Number Publication Date
CA2348514A1 true CA2348514A1 (fr) 2000-05-25

Family

ID=22321740

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002348514A Abandoned CA2348514A1 (fr) 1998-11-13 1999-11-12 Transplantation intra-uterine de cellules embryonnaires mesenchymateuses humaines

Country Status (5)

Country Link
EP (1) EP1128836A2 (fr)
JP (1) JP2002529509A (fr)
AU (1) AU1478000A (fr)
CA (1) CA2348514A1 (fr)
WO (1) WO2000029002A2 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004503255A (ja) * 2000-06-14 2004-02-05 ビスタジェン　インコーポレイテッド 間葉幹細胞を使用する毒性の分類
KR100865664B1 (ko) 2000-06-14 2008-10-29 비스타겐 인코포레이티드 간 줄기 세포를 사용하는 독성 타이핑
AU2002239306A1 (en) * 2000-11-15 2002-05-27 Osiris Therapeutics, Inc. Immunocompetent animals including xenogeneic implants of mesenchymal stem cells
WO2003047607A1 (fr) * 2001-12-06 2003-06-12 Sankyo Company, Limited Compositions medicales contenant des cellules amniotiques humaines
WO2007125916A1 (fr) * 2006-04-24 2007-11-08 Stemcell Institute Inc. Procede de preparation d'un organe en vue d'une transplantation
WO2012048276A2 (fr) 2010-10-08 2012-04-12 Caridianbct, Inc. Procédés et systèmes configurables pour la culture et la récolte de cellules dans un système de bioréacteur à fibres creuses
WO2015073918A1 (fr) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expansion de cellules dans un bioréacteur
CN106232800B (zh) 2014-03-25 2020-07-03 泰尔茂比司特公司 介质的被动替代
CN106715676A (zh) 2014-09-26 2017-05-24 泰尔茂比司特公司 按计划供养
WO2017004592A1 (fr) 2015-07-02 2017-01-05 Terumo Bct, Inc. Croissance cellulaire à l'aide de stimuli mécaniques
WO2017205667A1 (fr) 2016-05-25 2017-11-30 Terumo Bct, Inc. Expansion cellulaire
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
CN106806947A (zh) * 2017-01-13 2017-06-09 宁夏医科大学总医院 一种低免疫原性组织工程皮肤构建方法
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
CN110612344B (zh) 2017-03-31 2023-09-12 泰尔茂比司特公司 细胞扩增
WO2019040747A1 (fr) * 2017-08-23 2019-02-28 Wake Forest University Health Sciences Transplantation in utero de cellules exprimant le facteur viii pour le traitement de l'hémophilie
WO2020205969A1 (fr) * 2019-04-02 2020-10-08 The General Hospital Corporation Procédés pour améliorer la régénération de lymphocytes t
CN113941032B (zh) * 2020-07-16 2023-04-07 北京中卫医正科技有限公司 一种间充质干细胞复合补片及其制备方法与应用
CN113215084B (zh) * 2021-06-11 2023-04-07 中国农业科学院兰州兽医研究所 一种羊胎儿皮肤成纤维细胞、其分离方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5523226A (en) * 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods
WO1996028967A1 (fr) * 1995-03-17 1996-09-26 Chihiro Koike Mammiferes transgeniques autres que des primates, ou des serotypes de primates superieurs ont ete exprimes par un transfert de genes etrangers et procede pour creer ceux-ci
AU7238796A (en) * 1995-09-14 1997-04-01 Regents Of The University Of California, The Methods for inducing selected cell types
ATE286118T1 (de) * 1998-03-13 2005-01-15 Osiris Therapeutics Inc Anwendungen für humane nicht autologe, mesenchymale stammzellen

Also Published As

Publication number Publication date
EP1128836A2 (fr) 2001-09-05
WO2000029002A2 (fr) 2000-05-25
AU1478000A (en) 2000-06-05
WO2000029002A3 (fr) 2000-10-05
JP2002529509A (ja) 2002-09-10

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