CA2339871A1 - Acides nucleiques codant un purinorecepteur fonctionnel humain p2x2, et procedes de production et d'utilisation de ce dernier - Google Patents

Acides nucleiques codant un purinorecepteur fonctionnel humain p2x2, et procedes de production et d'utilisation de ce dernier Download PDF

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Publication number
CA2339871A1
CA2339871A1 CA002339871A CA2339871A CA2339871A1 CA 2339871 A1 CA2339871 A1 CA 2339871A1 CA 002339871 A CA002339871 A CA 002339871A CA 2339871 A CA2339871 A CA 2339871A CA 2339871 A1 CA2339871 A1 CA 2339871A1
Authority
CA
Canada
Prior art keywords
seq
receptor
cell
polynucleotide
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002339871A
Other languages
English (en)
Inventor
Kevin J. Lynch
Edward C. Burgard
Randy E. Metzger
Wende Niforatos
Edward B. Touma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2339871A1 publication Critical patent/CA2339871A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne un polypeptide de récepteur purinergique P2X¿2? de l'homme. L'invention traite aussi des molécules d'acide nucléique codant ledit polypeptide et des vecteurs et des cellules hôtes contenant ces molécules d'acide nucléique. En outre, l'invention a pour objet des procédés de production du polypeptide du récepteur P2X¿2?, et des procédés d'utilisation de ces polypeptides et des cellules hôtes qui expriment ces derniers afin de détecter les composés présentant une activé sur le récepteur P2X¿2?. En outre, l'invention concerne les utilisations thérapeutiques ce de récepteur.
CA002339871A 1998-08-20 1999-08-20 Acides nucleiques codant un purinorecepteur fonctionnel humain p2x2, et procedes de production et d'utilisation de ce dernier Abandoned CA2339871A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13745898A 1998-08-20 1998-08-20
US09/137,458 1998-08-20
PCT/US1999/019042 WO2000011167A2 (fr) 1998-08-20 1999-08-20 Acides nucleiques codant un purinorecepteur fonctionnel humain p2x2, et procedes de production et d'utilisation de ce dernier

Publications (1)

Publication Number Publication Date
CA2339871A1 true CA2339871A1 (fr) 2000-03-02

Family

ID=22477523

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002339871A Abandoned CA2339871A1 (fr) 1998-08-20 1999-08-20 Acides nucleiques codant un purinorecepteur fonctionnel humain p2x2, et procedes de production et d'utilisation de ce dernier

Country Status (4)

Country Link
EP (1) EP1104464A2 (fr)
JP (1) JP2002523043A (fr)
CA (1) CA2339871A1 (fr)
WO (1) WO2000011167A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10102050A1 (de) 2001-01-17 2002-07-18 Basf Ag Zubereitung zur Verbesserung der Nahrungsverwertung
EP1470145A4 (fr) * 2001-12-31 2005-05-25 Algos Therapeutics Inc Methodes et materiels destines a la modulation de p2x2
US20030203847A1 (en) * 2002-02-28 2003-10-30 Millennium Pharmaceuticals, Inc. Methods and compositions in treating pain and painful disorders using 9949, 14230, 760, 62553, 12216, 17719, 41897, 47174, 33408, 10002, 16209, 314, 636, 27410, 33260, 619, 15985, 69112, 2158, 224, 615, 44373, 95431, 22245, 2387, 16658, 55054, 16314, 1613, 1675, 9569 or 13424 molecules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10501122A (ja) * 1994-05-27 1998-02-03 グラクソ、グループ、リミテッド Ｐ▲下２ｘ▼レセプター（プリノセプターファミリー）
JP3885177B2 (ja) * 1997-03-26 2007-02-21 大塚製薬株式会社 ヒト遺伝子

Also Published As

Publication number Publication date
WO2000011167A3 (fr) 2000-10-05
WO2000011167A2 (fr) 2000-03-02
EP1104464A2 (fr) 2001-06-06
JP2002523043A (ja) 2002-07-30

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