CA2339871A1 - Nucleic acids encoding a functional human purinoreceptor p2x2 and methods of producing and use thereof - Google Patents

Nucleic acids encoding a functional human purinoreceptor p2x2 and methods of producing and use thereof Download PDF

Info

Publication number
CA2339871A1
CA2339871A1 CA002339871A CA2339871A CA2339871A1 CA 2339871 A1 CA2339871 A1 CA 2339871A1 CA 002339871 A CA002339871 A CA 002339871A CA 2339871 A CA2339871 A CA 2339871A CA 2339871 A1 CA2339871 A1 CA 2339871A1
Authority
CA
Canada
Prior art keywords
seq
receptor
cell
polynucleotide
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002339871A
Other languages
English (en)
French (fr)
Inventor
Kevin J. Lynch
Edward C. Burgard
Randy E. Metzger
Wende Niforatos
Edward B. Touma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2339871A1 publication Critical patent/CA2339871A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002339871A 1998-08-20 1999-08-20 Nucleic acids encoding a functional human purinoreceptor p2x2 and methods of producing and use thereof Abandoned CA2339871A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13745898A 1998-08-20 1998-08-20
US09/137,458 1998-08-20
PCT/US1999/019042 WO2000011167A2 (en) 1998-08-20 1999-08-20 Nucleic acids encoding a functional human purinoreceptor p2x2 and methods of producing and use thereof

Publications (1)

Publication Number Publication Date
CA2339871A1 true CA2339871A1 (en) 2000-03-02

Family

ID=22477523

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002339871A Abandoned CA2339871A1 (en) 1998-08-20 1999-08-20 Nucleic acids encoding a functional human purinoreceptor p2x2 and methods of producing and use thereof

Country Status (4)

Country Link
EP (1) EP1104464A2 (de)
JP (1) JP2002523043A (de)
CA (1) CA2339871A1 (de)
WO (1) WO2000011167A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10102050A1 (de) 2001-01-17 2002-07-18 Basf Ag Zubereitung zur Verbesserung der Nahrungsverwertung
US20080119423A1 (en) * 2001-12-31 2008-05-22 Shuster Samuel J Methods and Materials For Modulating p2x2
US20030203847A1 (en) * 2002-02-28 2003-10-30 Millennium Pharmaceuticals, Inc. Methods and compositions in treating pain and painful disorders using 9949, 14230, 760, 62553, 12216, 17719, 41897, 47174, 33408, 10002, 16209, 314, 636, 27410, 33260, 619, 15985, 69112, 2158, 224, 615, 44373, 95431, 22245, 2387, 16658, 55054, 16314, 1613, 1675, 9569 or 13424 molecules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995033048A2 (en) * 1994-05-27 1995-12-07 Glaxo Group Limited P2x receptors (purinoceptor family)
JP3885177B2 (ja) * 1997-03-26 2007-02-21 大塚製薬株式会社 ヒト遺伝子

Also Published As

Publication number Publication date
WO2000011167A2 (en) 2000-03-02
WO2000011167A3 (en) 2000-10-05
JP2002523043A (ja) 2002-07-30
EP1104464A2 (de) 2001-06-06

Similar Documents

Publication Publication Date Title
US6323000B2 (en) Variant human α7 acetylcholine receptor subunit, and methods of production and uses thereof
US5728808A (en) Human Prostaglandin receptor IP
US6358694B1 (en) Methods of identifying modulators of a prostaglandin receptor
JPH10179178A (ja) ヒト７回膜貫通型レセプター
JPH10262687A (ja) 新規ヒト１１ｃｂスプライス変種
US6391561B1 (en) Protein that enhances expression of potassium channels on cell surfaces and nucleic acids that encode the same
US20100221773A1 (en) Nucleic Acids Encoding a Functional Mammalin Purinoreceptor, P2X3, Methods of Production and Use Thereof
JP2002500633A (ja) Ｅｄｇ−１様受容体
US6242216B1 (en) Nucleic acids encoding a functional human purinoreceptor P2X2 and P2X4, and methods of production and use thereof
US6214581B1 (en) Nucleic acids encoding a functional human purinoreceptor P2X3 and P2X6, and methods of production and use thereof
JP2002505872A (ja) ７回膜貫通ｇタンパク質共役受容体ｅｃｒ６７３
CA2339871A1 (en) Nucleic acids encoding a functional human purinoreceptor p2x2 and methods of producing and use thereof
WO1999055901A2 (en) Screening assay for identifying human purinoreceptor ligands
US7547521B2 (en) Heteromultimeric ion channel receptor and uses thereof
WO1999036539A1 (en) Nucleic acids encoding a functional human purinoreceptor p2x3 and methods of production and use thereof
MXPA01001855A (en) Nucleic acids encoding a functional human purinoreceptor p2x2
US20020004222A1 (en) Cloning of a monkey 7TM receptor (AXOR8)
US7229779B2 (en) Variant human α7 acetylcholine receptor subunit, and methods of production and use thereof
US6355452B1 (en) Human histamine H3 gene variant-2
CA2370659A1 (en) The p2x3 receptor, methods of altering p2x3 receptor activity and uses thereof
GB2345487A (en) Polynucleotide and polypeptide sequence encoding rat mdr1a and screening methods thereof
MXPA00006974A (en) Nucleic acids encoding a functional human purinoreceptor p2x3
JPH10117791A (ja) ヒトｇタンパク質結合受容体ｈｌｙａｚ６１
WO2001016298A1 (en) Cloning of mouse gpr10 receptor
US20040106149A1 (en) Novel gpcr hfrbn63

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead