CA2335246A1 - Detection of cancer using cellular autofluorescence - Google Patents

Detection of cancer using cellular autofluorescence Download PDF

Info

Publication number
CA2335246A1
CA2335246A1 CA002335246A CA2335246A CA2335246A1 CA 2335246 A1 CA2335246 A1 CA 2335246A1 CA 002335246 A CA002335246 A CA 002335246A CA 2335246 A CA2335246 A CA 2335246A CA 2335246 A1 CA2335246 A1 CA 2335246A1
Authority
CA
Canada
Prior art keywords
tissue
light
accordance
intensity
fiber optic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002335246A
Other languages
English (en)
French (fr)
Inventor
Bhaskar Banerjee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/097,931 external-priority patent/US6405074B1/en
Application filed by Individual filed Critical Individual
Publication of CA2335246A1 publication Critical patent/CA2335246A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4222—Evaluating particular parts, e.g. particular organs
    • A61B5/4233—Evaluating particular parts, e.g. particular organs oesophagus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4318—Evaluation of the lower reproductive system
    • A61B5/4331—Evaluation of the lower reproductive system of the cervix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4375—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the male reproductive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Surgery (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Endoscopes (AREA)
CA002335246A 1998-06-16 1998-08-25 Detection of cancer using cellular autofluorescence Abandoned CA2335246A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/097,931 1998-06-16
US09/097,931 US6405074B1 (en) 1997-08-29 1998-06-16 Detection of cancer using cellular autofluorescence
PCT/US1998/017597 WO1999065394A1 (en) 1998-06-16 1998-08-25 Detection of cancer using cellular autofluorescence

Publications (1)

Publication Number Publication Date
CA2335246A1 true CA2335246A1 (en) 1999-12-23

Family

ID=22265822

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002335246A Abandoned CA2335246A1 (en) 1998-06-16 1998-08-25 Detection of cancer using cellular autofluorescence

Country Status (6)

Country Link
EP (1) EP1087698A4 (ja)
JP (1) JP2002518664A (ja)
CN (1) CN1301137A (ja)
AU (1) AU9119498A (ja)
CA (1) CA2335246A1 (ja)
WO (1) WO1999065394A1 (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6364829B1 (en) 1999-01-26 2002-04-02 Newton Laboratories, Inc. Autofluorescence imaging system for endoscopy
NZ529432A (en) 1999-01-26 2005-07-29 Newton Lab Inc Autofluorescence imaging system for endoscopy
EP1239771B1 (en) * 1999-12-22 2004-10-06 Xillix Technologies Corp. Portable system for detecting skin abnormalities
GB0030310D0 (en) * 2000-12-13 2001-01-24 Medical Res Council Apparatus and method for imaging a histological sample
US6636623B2 (en) * 2001-08-10 2003-10-21 Visiongate, Inc. Optical projection imaging system and method for automatically detecting cells with molecular marker compartmentalization associated with malignancy and disease
CN100405976C (zh) * 2002-04-14 2008-07-30 王念勇 利用固有荧光诊断早期肿瘤的诊断仪
DE10255013B4 (de) * 2002-11-25 2004-12-09 Siemens Ag Verfahren und Vorrichtung zur Lokalisierung von Licht emittierenden Bereichen
EP1807000A1 (en) * 2004-09-24 2007-07-18 Art Advanced Research Technologies Inc. Optical imaging method for tissue characterization
JP5698483B2 (ja) * 2010-09-22 2015-04-08 オリンパス株式会社 蛍光観察装置
WO2014014956A1 (en) 2012-07-17 2014-01-23 The Arizona Board Of Regents On Behalf Of The University Of Arizona Formulaic imaging for tissue diagnosis
CN105748149B (zh) * 2016-04-20 2019-02-01 叶莹 一种用于癌症手术荧光导航和残癌示踪与清除的设备
CN106226275A (zh) * 2016-07-15 2016-12-14 上海交通大学 一种基于指甲自荧光作为检测脑卒中发病的生物标志物的检测方法及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5131398A (en) * 1990-01-22 1992-07-21 Mediscience Technology Corp. Method and apparatus for distinguishing cancerous tissue from benign tumor tissue, benign tissue or normal tissue using native fluorescence
CA2042075C (en) * 1991-05-08 2001-01-23 Branko Palcic Endoscopic imaging system
US5612540A (en) * 1995-03-31 1997-03-18 Board Of Regents, The University Of Texas Systems Optical method for the detection of cervical neoplasias using fluorescence spectroscopy

Also Published As

Publication number Publication date
AU9119498A (en) 2000-01-05
WO1999065394A1 (en) 1999-12-23
JP2002518664A (ja) 2002-06-25
EP1087698A1 (en) 2001-04-04
CN1301137A (zh) 2001-06-27
EP1087698A4 (en) 2003-09-03

Similar Documents

Publication Publication Date Title
US6405070B1 (en) Detection of cancer using cellular autofluorescence
JP3683271B2 (ja) 積分された内部蛍光を使用して病気の組織の画像を映すための装置および方法
JP4217403B2 (ja) 組織病巣の特徴付けおよびマッピングのためのシステム
US7697975B2 (en) Methods and apparatus for fluorescence imaging using multiple excitation-emission pairs and simultaneous multi-channel image detection
JP3236085B2 (ja) 内視鏡装置
US20120123205A1 (en) Additional systems and methods for providing real-time anatomical guidance in a disgnostic or therapeutic procedure
JPH0654792A (ja) 撮像装置
US20080004495A1 (en) Endoscope
US20090326359A1 (en) Method of in vivo detection and/or diagnosis of cancer using fluorescence based dna image cytometry
US6405074B1 (en) Detection of cancer using cellular autofluorescence
CA2335246A1 (en) Detection of cancer using cellular autofluorescence
JP2007528505A (ja) マルチチャンネル光学画像法
JP2005312979A (ja) 撮像装置
WO2017142376A1 (ko) 말초신경의 선택적 검경을 위한 무표지 영상화 시스템
KR20180066645A (ko) 형광 내시경 시스템
MacAulay et al. Optical properties of normal and malignant tissues in the nasopharynx and larynx
RU2152162C1 (ru) Способ повышения точности обнаружения злокачественных новообразований и определения границ их локализации
Lin et al. Clinical translation of ultraviolet autofluorescence microscopy towards endomicroscopy for early detection of cancer
Soobhanath Clinical Microendoscopy for the Mapping of Tumor Margins using a Support Template for Near-Continuous Imaging
Lovisa Endoscopic fluorescence imaging: spectral optimization and in vivo characterization of positive sites by magnifying vascular imaging
Lin et al. Visualization of epithelial morphology using autofluorescence microscopy under ultraviolet excitation
Wu et al. Detecting neoplastic growths in vivo with autofluorescence imaging

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued