CA2331374C - Procede de conservation de longue duree de molecules d'adn et conditionnement pour sa mise en oeuvre - Google Patents
Procede de conservation de longue duree de molecules d'adn et conditionnement pour sa mise en oeuvre Download PDFInfo
- Publication number
- CA2331374C CA2331374C CA2331374A CA2331374A CA2331374C CA 2331374 C CA2331374 C CA 2331374C CA 2331374 A CA2331374 A CA 2331374A CA 2331374 A CA2331374 A CA 2331374A CA 2331374 C CA2331374 C CA 2331374C
- Authority
- CA
- Canada
- Prior art keywords
- dna
- capsule
- encapsulation
- polymer
- metal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title claims abstract description 31
- 238000004806 packaging method and process Methods 0.000 title claims abstract description 11
- 230000002035 prolonged effect Effects 0.000 title abstract description 3
- 239000002775 capsule Substances 0.000 claims abstract description 38
- 229910052751 metal Inorganic materials 0.000 claims abstract description 11
- 239000002184 metal Substances 0.000 claims abstract description 11
- 108020004414 DNA Proteins 0.000 claims description 76
- 102000053602 DNA Human genes 0.000 claims description 64
- 238000005538 encapsulation Methods 0.000 claims description 22
- 229920001577 copolymer Polymers 0.000 claims description 18
- 239000000126 substance Substances 0.000 claims description 14
- 238000004321 preservation Methods 0.000 claims description 12
- 238000000746 purification Methods 0.000 claims description 7
- 238000000605 extraction Methods 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 6
- 239000011521 glass Substances 0.000 claims description 5
- 239000011261 inert gas Substances 0.000 claims description 5
- 230000007774 longterm Effects 0.000 claims description 5
- 239000002904 solvent Substances 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 230000001476 alcoholic effect Effects 0.000 claims description 4
- 239000011248 coating agent Substances 0.000 claims description 4
- 238000000576 coating method Methods 0.000 claims description 4
- 229920000642 polymer Polymers 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- 230000002378 acidificating effect Effects 0.000 claims description 3
- 150000003839 salts Chemical class 0.000 claims description 3
- 230000035939 shock Effects 0.000 claims description 3
- 239000000654 additive Substances 0.000 claims description 2
- 239000000919 ceramic Substances 0.000 claims description 2
- 239000002131 composite material Substances 0.000 claims description 2
- 238000011109 contamination Methods 0.000 claims description 2
- 229910001385 heavy metal Inorganic materials 0.000 claims description 2
- 239000005361 soda-lime glass Substances 0.000 claims description 2
- 150000002500 ions Chemical class 0.000 claims 1
- 229910001092 metal group alloy Inorganic materials 0.000 claims 1
- 150000002739 metals Chemical class 0.000 claims 1
- 230000009972 noncorrosive effect Effects 0.000 abstract 1
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- 230000002068 genetic effect Effects 0.000 description 6
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 5
- 229910052737 gold Inorganic materials 0.000 description 5
- 239000010931 gold Substances 0.000 description 5
- 230000005855 radiation Effects 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 230000005865 ionizing radiation Effects 0.000 description 4
- 230000003647 oxidation Effects 0.000 description 4
- 238000007254 oxidation reaction Methods 0.000 description 4
- 230000016571 aggressive behavior Effects 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 230000003750 conditioning effect Effects 0.000 description 3
- 235000019441 ethanol Nutrition 0.000 description 3
- 229920002125 Sokalan® Polymers 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- 230000004075 alteration Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000006460 hydrolysis reaction Methods 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 239000004584 polyacrylic acid Substances 0.000 description 2
- 238000006116 polymerization reaction Methods 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 1
- 229920000936 Agarose Polymers 0.000 description 1
- 206010001488 Aggression Diseases 0.000 description 1
- 230000005778 DNA damage Effects 0.000 description 1
- 231100000277 DNA damage Toxicity 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- ZOIORXHNWRGPMV-UHFFFAOYSA-N acetic acid;zinc Chemical compound [Zn].CC(O)=O.CC(O)=O ZOIORXHNWRGPMV-UHFFFAOYSA-N 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000007073 chemical hydrolysis Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- OPQARKPSCNTWTJ-UHFFFAOYSA-L copper(ii) acetate Chemical compound [Cu+2].CC([O-])=O.CC([O-])=O OPQARKPSCNTWTJ-UHFFFAOYSA-L 0.000 description 1
- 238000002788 crimping Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000006862 enzymatic digestion Effects 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 230000007071 enzymatic hydrolysis Effects 0.000 description 1
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 210000003550 mucous cell Anatomy 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000004246 zinc acetate Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Packages (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Preventing Corrosion Or Incrustation Of Metals (AREA)
- Extraction Or Liquid Replacement (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Packging For Living Organisms, Food Or Medicinal Products That Are Sensitive To Environmental Conditiond (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/FR1998/000912 WO1999057264A1 (fr) | 1998-05-06 | 1998-05-06 | Procede de conservation de longue duree de molecules d'adn et conditionnement pour sa mise en oeuvre |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2331374A1 CA2331374A1 (fr) | 1999-11-11 |
| CA2331374C true CA2331374C (fr) | 2011-04-19 |
Family
ID=9522263
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2331374A Expired - Fee Related CA2331374C (fr) | 1998-05-06 | 1998-05-06 | Procede de conservation de longue duree de molecules d'adn et conditionnement pour sa mise en oeuvre |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6461571B1 (pt) |
| EP (1) | EP1075515B1 (pt) |
| JP (1) | JP5214081B2 (pt) |
| KR (1) | KR100512702B1 (pt) |
| CN (1) | CN1198925C (pt) |
| AT (1) | ATE303436T1 (pt) |
| AU (1) | AU770977B2 (pt) |
| BR (1) | BR9815842B1 (pt) |
| CA (1) | CA2331374C (pt) |
| DE (1) | DE69831429T2 (pt) |
| ES (1) | ES2248902T3 (pt) |
| HK (1) | HK1039499A1 (pt) |
| HU (1) | HU225770B1 (pt) |
| IL (2) | IL139465A0 (pt) |
| NO (1) | NO327582B1 (pt) |
| NZ (1) | NZ507970A (pt) |
| PL (1) | PL191861B1 (pt) |
| WO (1) | WO1999057264A1 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2228617C2 (ru) * | 2002-10-09 | 2004-05-20 | Заславский Андрей Станиславович | Способ длительного хранения биологического материала |
| WO2005090563A1 (ja) * | 2004-03-23 | 2005-09-29 | Nisshinbo Industries, Inc. | 核酸溶解用溶媒、核酸含有溶液および核酸保存方法 |
| KR100597799B1 (ko) * | 2005-02-03 | 2006-07-06 | 시너지씨엔씨(주) | 유전자 리셉터클, 그 제조방법 및 이를 이용한 ｄｎａ보관방법 |
| US8415138B2 (en) * | 2006-08-31 | 2013-04-09 | Agilent Technologies, Inc. | Apparatuses and methods for oligonucleotide preparation |
| US20080058511A1 (en) * | 2006-08-31 | 2008-03-06 | John Hargreaves | Methods and compositions useful in the preparation of oligonucleotides |
| FR2928632B1 (fr) | 2008-03-11 | 2012-06-01 | Imagene | Contenant destine a recevoir et conserver du materiel biologique, notamment de l'adn |
| KR20100106261A (ko) * | 2010-08-24 | 2010-10-01 | 최민성 | 유전자 보존 및 생전기록 보관 장사 방법 |
| JP2017503860A (ja) * | 2014-01-10 | 2017-02-02 | チャンバー ワークス，エルエルシー | 皮膚への適用または刺青インクへの添加のための個別化物質およびその製造方法 |
| FR3077509B1 (fr) | 2018-02-05 | 2021-12-24 | L Etat Francais Represente Par Le Mini De L Interieur | Dispositif de stockage a temperature ambiante de materiels biologiques |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3200085A (en) * | 1959-03-02 | 1965-08-10 | Arthur L Barber Jr | Radiation barrier material and method of making the same |
| US3609372A (en) * | 1963-06-04 | 1971-09-28 | Marxen Friedrich | Shaped polymeric shield against neutron and gamma radiation |
| CA1244347A (en) * | 1984-05-29 | 1988-11-08 | Eddie H. Massey | Stabilized insulin formulations |
| FR2597651B1 (fr) * | 1986-04-16 | 1989-12-08 | Aerospatiale | Materiau de protection contre les rayons x et procedes de fabrication de ce materiau |
| US4806368A (en) * | 1987-09-16 | 1989-02-21 | Reddy Malireddy S | Shelf life and subsequent growth of lactobacillus acidophilus, propionibacterium shermanii and leuconostoc citrovorum in dietary fiber based supplement preparation |
| EP0387348A4 (en) * | 1988-09-12 | 1992-07-08 | Johannes Smid | Homogeneous radiopaque polymer-organobismuth composites |
| WO1990003959A1 (en) * | 1988-10-05 | 1990-04-19 | The Flinders University Of South Australia | Solid medium and method for dna storage |
| GB8903593D0 (en) * | 1989-02-16 | 1989-04-05 | Pafra Ltd | Storage of materials |
| DE4119574A1 (de) * | 1991-06-14 | 1992-12-17 | Diagen Inst Molekularbio | Verfahren zur lagerung und/oder zum transport von nukleinsaeuren |
| US5565318A (en) * | 1994-09-02 | 1996-10-15 | Pharmacia Biotech, Inc. | Room temperature stable reagent semi-spheres |
| FR2755440B1 (fr) * | 1996-11-07 | 1999-01-15 | Tuffet Sophie | Procede de conservation de longue duree de molecules d'adn et conditionnement pour sa mise en oeuvre |
| DE29715707U1 (de) * | 1997-09-02 | 1998-01-02 | Huber, Matthias C., Dr.rer.nat., 79232 March | In transparentem Kunststoff fixierte, ungelöste, für das menschliche Auge in ihrer Gesamtheit sichtbare, aus pflanzlichem oder tierischem Zellmaterial präparierte genomische DNS (Desoxyribonukleinsäure)-Moleküle |
-
1998
- 1998-05-06 PL PL345095A patent/PL191861B1/pl unknown
- 1998-05-06 CN CNB98814106XA patent/CN1198925C/zh not_active Expired - Fee Related
- 1998-05-06 NZ NZ507970A patent/NZ507970A/en not_active IP Right Cessation
- 1998-05-06 AT AT98924390T patent/ATE303436T1/de active
- 1998-05-06 KR KR10-2000-7012374A patent/KR100512702B1/ko not_active IP Right Cessation
- 1998-05-06 AU AU76603/98A patent/AU770977B2/en not_active Ceased
- 1998-05-06 EP EP98924390A patent/EP1075515B1/fr not_active Expired - Lifetime
- 1998-05-06 US US09/674,704 patent/US6461571B1/en not_active Expired - Lifetime
- 1998-05-06 JP JP2000547219A patent/JP5214081B2/ja not_active Expired - Fee Related
- 1998-05-06 HU HU0102541A patent/HU225770B1/hu not_active IP Right Cessation
- 1998-05-06 CA CA2331374A patent/CA2331374C/fr not_active Expired - Fee Related
- 1998-05-06 BR BRPI9815842-2A patent/BR9815842B1/pt not_active IP Right Cessation
- 1998-05-06 IL IL13946598A patent/IL139465A0/xx active IP Right Grant
- 1998-05-06 DE DE69831429T patent/DE69831429T2/de not_active Expired - Lifetime
- 1998-05-06 WO PCT/FR1998/000912 patent/WO1999057264A1/fr active IP Right Grant
- 1998-05-06 ES ES98924390T patent/ES2248902T3/es not_active Expired - Lifetime
-
2000
- 2000-11-03 NO NO20005546A patent/NO327582B1/no not_active IP Right Cessation
- 2000-11-05 IL IL139465A patent/IL139465A/en not_active IP Right Cessation
-
2001
- 2001-10-18 HK HK01107294A patent/HK1039499A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU770977B2 (en) | 2004-03-11 |
| HUP0102541A3 (en) | 2003-04-28 |
| CA2331374A1 (fr) | 1999-11-11 |
| HUP0102541A2 (hu) | 2001-11-28 |
| EP1075515A1 (fr) | 2001-02-14 |
| IL139465A (en) | 2008-03-20 |
| NO20005546D0 (no) | 2000-11-03 |
| KR100512702B1 (ko) | 2005-09-07 |
| PL191861B1 (pl) | 2006-07-31 |
| PL345095A1 (en) | 2001-12-03 |
| NO327582B1 (no) | 2009-08-24 |
| CN1198925C (zh) | 2005-04-27 |
| ATE303436T1 (de) | 2005-09-15 |
| JP5214081B2 (ja) | 2013-06-19 |
| KR20010043362A (ko) | 2001-05-25 |
| HU225770B1 (en) | 2007-08-28 |
| AU7660398A (en) | 1999-11-23 |
| CN1299412A (zh) | 2001-06-13 |
| DE69831429T2 (de) | 2006-06-29 |
| WO1999057264A1 (fr) | 1999-11-11 |
| ES2248902T3 (es) | 2006-03-16 |
| NZ507970A (en) | 2003-09-26 |
| HK1039499A1 (en) | 2002-04-26 |
| JP2002513567A (ja) | 2002-05-14 |
| BR9815842B1 (pt) | 2010-10-19 |
| IL139465A0 (en) | 2001-11-25 |
| EP1075515B1 (fr) | 2005-08-31 |
| BR9815842A (pt) | 2001-01-09 |
| DE69831429D1 (de) | 2005-10-06 |
| US6461571B1 (en) | 2002-10-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20180507 |