CA2294155A1 - Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals - Google Patents
Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals Download PDFInfo
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- CA2294155A1 CA2294155A1 CA002294155A CA2294155A CA2294155A1 CA 2294155 A1 CA2294155 A1 CA 2294155A1 CA 002294155 A CA002294155 A CA 002294155A CA 2294155 A CA2294155 A CA 2294155A CA 2294155 A1 CA2294155 A1 CA 2294155A1
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
Landscapes
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- Organic Chemistry (AREA)
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- Biomedical Technology (AREA)
- Neurology (AREA)
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- Epidemiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US5040297P | 1997-06-20 | 1997-06-20 | |
| US60/050,402 | 1997-06-20 | ||
| PCT/US1998/012231 WO1998058636A1 (en) | 1997-06-20 | 1998-06-15 | Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals |
Publications (1)
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| CA2294155A1 true CA2294155A1 (en) | 1998-12-30 |
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| CA002294155A Abandoned CA2294155A1 (en) | 1997-06-20 | 1998-06-15 | Analgesic methods using synthetic catalysts for the dismutation of superoxide radicals |
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|---|---|
| US (2) | US6180620B1 (OSRAM) |
| EP (1) | EP1001752B1 (OSRAM) |
| JP (1) | JP2002506445A (OSRAM) |
| AT (1) | ATE256467T1 (OSRAM) |
| AU (1) | AU733415B2 (OSRAM) |
| CA (1) | CA2294155A1 (OSRAM) |
| DE (1) | DE69820633T2 (OSRAM) |
| DK (1) | DK1001752T3 (OSRAM) |
| ES (1) | ES2215305T3 (OSRAM) |
| PT (1) | PT1001752E (OSRAM) |
| WO (1) | WO1998058636A1 (OSRAM) |
| ZA (1) | ZA985376B (OSRAM) |
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| US6127356A (en) | 1993-10-15 | 2000-10-03 | Duke University | Oxidant scavengers |
| US20050171198A1 (en) * | 1997-06-20 | 2005-08-04 | Metaphore Pharmaceuticals, Inc. | SODm therapy for treatment, prevention, inhibition and reversal of inflammatory disease |
| US20060270639A1 (en) * | 1997-06-20 | 2006-11-30 | Daniela Salvemini | Combinations of superoxide dismutase mimetics and nonsteroidal analgesic/anti-inflammatory drugs |
| US6214817B1 (en) * | 1997-06-20 | 2001-04-10 | Monsanto Company | Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity |
| JP2001521939A (ja) | 1997-11-03 | 2001-11-13 | デューク・ユニバーシティー | 置換されたポルフィリン類 |
| EP1155019B1 (en) | 1999-01-25 | 2005-12-07 | National Jewish Medical and Research Center | Substituted porphyrins and their therapeutic use |
| US7445641B1 (en) * | 1999-05-27 | 2008-11-04 | Pharmacia Corporation | Biomaterials modified with superoxide dismutase mimics |
| US20030069281A1 (en) * | 2000-06-14 | 2003-04-10 | Irwin Fridovich | Tetrapyrroles |
| US20020072512A1 (en) * | 2000-12-08 | 2002-06-13 | Metaphore Pharmaceuticals, Inc | Method of preventing and treating HIV-mediated central nervous system damage |
| EP1347773B1 (en) * | 2001-01-05 | 2010-04-14 | Metaphore Pharmaceuticals Inc. | Compositions and methods for enhancing cytokine activity and treating hypotension associated with the administration of cytokines |
| JP2004520380A (ja) * | 2001-01-19 | 2004-07-08 | ナショナル・ジュウィッシュ・メディカル・アンド・リサーチ・センター | 癌治療本出願は、２００１年１月１９日に出願の仮出願番号第６０／２６２，３９０号の優先権を主張し、その全ての内容は、参照により本願明細書に援用したものとする。 |
| WO2002058686A2 (en) * | 2001-01-26 | 2002-08-01 | Metaphore Pharmaceuticals, Inc. | Method of treatment of neurodegenerative disorders using pentaaza-macrocyclic ligand complexes |
| US20040137638A1 (en) | 2002-03-04 | 2004-07-15 | Slomczynska Urszula J. | Chromatography of metal complexes |
| EP1405066B1 (en) * | 2001-03-02 | 2015-06-17 | Galera Therapeutics LLC | Chromatography of metal complexes |
| JP2005508864A (ja) * | 2001-06-01 | 2005-04-07 | ナショナル・ジュウィッシュ・メディカル・アンド・リサーチ・センター | 糖尿病の治療、または移植術における使用、または免疫寛容の誘導のためのオキシダントスカベンジャー |
| AU2002315001A1 (en) * | 2001-06-08 | 2002-12-23 | Metaphore Pharmaceuticals, Inc. | Libraries of conformationally constrained peptides, chiral azacrowns, and peptidomimetics and methods of making the same |
| MXPA03011795A (es) * | 2001-06-26 | 2005-10-18 | Metaphore Pharmaceuticals Inc | Terapia de combinacion de una superoxido dismutasa mimetica y un corticosteroide para la prevencion y/o el tratamiento de una enfermedad inflamatoria. |
| CA2464528A1 (en) * | 2001-11-02 | 2003-05-15 | Elan Corporation, Plc | Pharmaceutical composition |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JPH0751496B2 (ja) | 1986-04-02 | 1995-06-05 | 武田薬品工業株式会社 | リポソ−ムの製造法 |
| US5216021A (en) | 1986-08-28 | 1993-06-01 | Sorenson John R J | Analgesic method |
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| JPS63313581A (ja) * | 1987-06-16 | 1988-12-21 | Ube Ind Ltd | 修飾ス−パ−オキシドジスムタ−ゼ |
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| CN1088086A (zh) * | 1992-12-14 | 1994-06-22 | 西北大学 | 一种新型的护肤保健品 |
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| JP2000508625A (ja) | 1996-03-13 | 2000-07-11 | モンサント カンパニー | スーパーオキシドをジスムテートする触媒として有効な窒素含有大環状リガンドのマンガンまたは鉄錯体の生体分子結合体 |
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1998
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- 1998-06-15 JP JP50459399A patent/JP2002506445A/ja not_active Ceased
- 1998-06-15 DE DE69820633T patent/DE69820633T2/de not_active Expired - Fee Related
- 1998-06-15 AU AU80685/98A patent/AU733415B2/en not_active Ceased
- 1998-06-15 CA CA002294155A patent/CA2294155A1/en not_active Abandoned
- 1998-06-15 DK DK98929022T patent/DK1001752T3/da active
- 1998-06-15 PT PT98929022T patent/PT1001752E/pt unknown
- 1998-06-15 AT AT98929022T patent/ATE256467T1/de not_active IP Right Cessation
- 1998-06-15 ES ES98929022T patent/ES2215305T3/es not_active Expired - Lifetime
- 1998-06-15 EP EP98929022A patent/EP1001752B1/en not_active Expired - Lifetime
- 1998-06-15 WO PCT/US1998/012231 patent/WO1998058636A1/en not_active Ceased
- 1998-06-19 ZA ZA985376A patent/ZA985376B/xx unknown
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2000
- 2000-08-09 US US09/634,152 patent/US6395725B1/en not_active Expired - Fee Related
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| ES2215305T3 (es) | 2004-10-01 |
| AU8068598A (en) | 1999-01-04 |
| JP2002506445A (ja) | 2002-02-26 |
| ZA985376B (en) | 1999-06-21 |
| AU733415B2 (en) | 2001-05-17 |
| PT1001752E (pt) | 2004-05-31 |
| EP1001752A1 (en) | 2000-05-24 |
| ATE256467T1 (de) | 2004-01-15 |
| EP1001752B1 (en) | 2003-12-17 |
| DK1001752T3 (da) | 2004-04-19 |
| US6180620B1 (en) | 2001-01-30 |
| DE69820633T2 (de) | 2004-09-23 |
| WO1998058636A1 (en) | 1998-12-30 |
| DE69820633D1 (de) | 2004-01-29 |
| US6395725B1 (en) | 2002-05-28 |
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| EEER | Examination request | ||
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Effective date: 20080616 |