CA2289992A1 - Reduction d'halogenures aromatiques - Google Patents

Reduction d'halogenures aromatiques Download PDF

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Publication number
CA2289992A1
CA2289992A1 CA002289992A CA2289992A CA2289992A1 CA 2289992 A1 CA2289992 A1 CA 2289992A1 CA 002289992 A CA002289992 A CA 002289992A CA 2289992 A CA2289992 A CA 2289992A CA 2289992 A1 CA2289992 A1 CA 2289992A1
Authority
CA
Canada
Prior art keywords
oxygen
reduction
lialh4
reduced
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002289992A
Other languages
English (en)
Inventor
Laszlo Czollner
Ulrich Jordis
Johannes Frohlich
Bernhard Kuenburg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanochemia Pharmazeutika AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2289992A1 publication Critical patent/CA2289992A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B31/00—Reduction in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C07C1/26—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only halogen atoms as hetero-atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/08—Hydrogen atoms or radicals containing only hydrogen and carbon atoms
    • C07D333/10—Thiophene

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

L'invention concerne la réduction d'halogénures (hétéro)aromatiques de la formule générale (I) Ar-X¿n? en composés de la formule générale (II) Ar-H¿n?, réduction dans laquelle on utilise un agent de réduction, en particulier un réactif hydrure comme l'hydrure d'aluminium et de lithium (LiAlH¿4?), en présence d'oxygène, en particulier sous forme d'un mélange d'oxygène et de gaz inerte. La réduction en présence d'oxygène donne de bons rendements pour des temps de réaction courts même dans des installations semi-industrielles ou industrielles. La réduction avec LiAlH¿4? en présence d'oxygène convient également à la réduction d'halogénures hétéroaromatiques complexes, par exemple à la réduction de cétal de bromonarwedine en cétal de narwedine à échelle industrielle.
CA002289992A 1997-05-21 1998-04-30 Reduction d'halogenures aromatiques Abandoned CA2289992A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ATA865/97 1997-05-21
AT0086597A AT405051B (de) 1997-05-21 1997-05-21 Reduktion aromatischer halogenide
PCT/AT1998/000112 WO1998052885A1 (fr) 1997-05-21 1998-04-30 Reduction d'halogenures aromatiques

Publications (1)

Publication Number Publication Date
CA2289992A1 true CA2289992A1 (fr) 1998-11-26

Family

ID=3501602

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002289992A Abandoned CA2289992A1 (fr) 1997-05-21 1998-04-30 Reduction d'halogenures aromatiques

Country Status (15)

Country Link
EP (1) EP0983215A1 (fr)
JP (1) JP2001525828A (fr)
KR (1) KR20010012795A (fr)
CN (1) CN1257467A (fr)
AT (1) AT405051B (fr)
AU (1) AU7012798A (fr)
BG (1) BG103880A (fr)
BR (1) BR9809661A (fr)
CA (1) CA2289992A1 (fr)
HU (1) HUP0004681A2 (fr)
NO (1) NO995494D0 (fr)
NZ (1) NZ500733A (fr)
PL (1) PL336906A1 (fr)
SK (1) SK158399A3 (fr)
WO (1) WO1998052885A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006018703A2 (fr) * 2004-08-16 2006-02-23 Ranbaxy Laboratories Limited Procedes de preparation de la narwedine et son utilisation dans la synthese de galantamine
WO2012073973A1 (fr) * 2010-12-02 2012-06-07 横浜ゴム株式会社 Pneu équipé de dispositif d'acquisition d'informations
CN107602318B (zh) * 2017-09-08 2020-06-05 郑州大学 一种温和条件下卤代芳烃液相还原脱卤的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3839329A1 (de) * 1988-11-22 1990-05-31 Basf Ag Verfahren zur reduktiven enthalogenierung von aromaten

Also Published As

Publication number Publication date
BG103880A (en) 2000-06-30
BR9809661A (pt) 2000-07-11
AT405051B (de) 1999-05-25
KR20010012795A (ko) 2001-02-26
NO995494L (no) 1999-11-10
HUP0004681A2 (hu) 2001-04-28
EP0983215A1 (fr) 2000-03-08
AU7012798A (en) 1998-12-11
NO995494D0 (no) 1999-11-10
SK158399A3 (en) 2000-07-11
ATA86597A (de) 1998-09-15
NZ500733A (en) 2001-03-30
JP2001525828A (ja) 2001-12-11
CN1257467A (zh) 2000-06-21
PL336906A1 (en) 2000-07-17
WO1998052885A1 (fr) 1998-11-26

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Legal Events

Date Code Title Description
FZDE Discontinued