CA2288287A1 - Compositions solides concues pour une administration orale et comprenant un fumarate de magnesium et de l-carnitine ou un fumarate de magnesium et d'alcanoyle-l-carnitine - Google Patents
Compositions solides concues pour une administration orale et comprenant un fumarate de magnesium et de l-carnitine ou un fumarate de magnesium et d'alcanoyle-l-carnitine Download PDFInfo
- Publication number
- CA2288287A1 CA2288287A1 CA002288287A CA2288287A CA2288287A1 CA 2288287 A1 CA2288287 A1 CA 2288287A1 CA 002288287 A CA002288287 A CA 002288287A CA 2288287 A CA2288287 A CA 2288287A CA 2288287 A1 CA2288287 A1 CA 2288287A1
- Authority
- CA
- Canada
- Prior art keywords
- carnitine
- alkanoyl
- solid compositions
- oral administration
- compositions suitable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- QUIOHQITLKCGNW-TYYBGVCCSA-L magnesium;(e)-but-2-enedioate Chemical compound [Mg+2].[O-]C(=O)\C=C\C([O-])=O QUIOHQITLKCGNW-TYYBGVCCSA-L 0.000 title abstract 2
- 239000008247 solid mixture Substances 0.000 title abstract 2
- 229960001518 levocarnitine Drugs 0.000 title 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title 1
- 235000015872 dietary supplement Nutrition 0.000 abstract 2
- 230000000378 dietary effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000013589 supplement Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/13—Dicarboxylic acids
- C07C57/15—Fumaric acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Animal Husbandry (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT97RM000254A IT1290600B1 (it) | 1997-04-30 | 1997-04-30 | Composizioni solide atte alla somministrazione orale comprendenti l-carnitina e alcanoil l-carnitine magnesio fumarato |
ITRM97A000254 | 1997-04-30 | ||
PCT/IT1998/000079 WO1998049134A1 (fr) | 1997-04-30 | 1998-04-08 | Compositions solides concues pour une administration orale et comprenant un fumarate de magnesium et de l-carnitine ou un fumarate de magnesium et d'alcanoyle-l-carnitine |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2288287A1 true CA2288287A1 (fr) | 1998-11-05 |
CA2288287C CA2288287C (fr) | 2008-06-10 |
Family
ID=11405029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002288287A Expired - Fee Related CA2288287C (fr) | 1997-04-30 | 1998-04-08 | Compositions solides concues pour une administration orale et comprenant un fumarate de magnesium et de l-carnitine ou un fumarate de magnesium et d'alcanoyle-l-carnitine |
Country Status (22)
Country | Link |
---|---|
US (1) | US6051608A (fr) |
EP (1) | EP0979224B1 (fr) |
JP (1) | JP2001524106A (fr) |
KR (1) | KR100556238B1 (fr) |
CN (1) | CN1137088C (fr) |
AT (1) | ATE220659T1 (fr) |
AU (1) | AU733008B2 (fr) |
BR (1) | BR9809368A (fr) |
CA (1) | CA2288287C (fr) |
CZ (1) | CZ290159B6 (fr) |
DE (1) | DE69806590T2 (fr) |
DK (1) | DK0979224T3 (fr) |
ES (1) | ES2179485T3 (fr) |
HK (1) | HK1025559A1 (fr) |
HU (1) | HUP0002198A3 (fr) |
IL (2) | IL132275A0 (fr) |
IT (1) | IT1290600B1 (fr) |
NZ (1) | NZ500536A (fr) |
PL (1) | PL189602B1 (fr) |
PT (1) | PT979224E (fr) |
SK (1) | SK283818B6 (fr) |
WO (1) | WO1998049134A1 (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000030637A1 (fr) * | 1998-11-26 | 2000-06-02 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Utilisation d'un sel de fumarate de l carnitine, ou de ses derives alcanoyles, pour lutter contre l'ischemie |
IT1305308B1 (it) * | 1999-03-26 | 2001-05-04 | Biosint S P A | Granulato ad alto contenuto di l-carnitina o alcanoil-l-carnitina,particolarmente adatto alla produzione di compresse per compressione |
US6914076B2 (en) * | 2000-01-19 | 2005-07-05 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Treating chronic uremic patients undergoing periodical dialysis |
US6429230B1 (en) * | 2000-01-19 | 2002-08-06 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Treating chronic uremic patients undergoing periodical dialysis |
US6335369B1 (en) * | 2000-01-19 | 2002-01-01 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Treating chronic uremic patients undergoing periodical dialysis |
KR20010084849A (ko) * | 2000-02-29 | 2001-09-06 | 손 경 식 | L-카르니틴을 이용한 기능성 우유 및 그 제조 방법 |
EP1326502B1 (fr) * | 2000-08-29 | 2005-05-18 | Lonza Ag | Procede de fabrication d'un melange pouvant etre granule et hydroxycitrate de carnitine et de magnesium |
DE10133200A1 (de) * | 2001-07-07 | 2003-01-23 | Beiersdorf Ag | Carnitin enthaltende kosmetische und dermatologische Zubereitungen zur Behandlung und aktiven Prävention trockener Haut und anderer negativer Veränderungen der physiologischen Homöostase der gesunden Haut |
ITRM20010695A1 (it) * | 2001-11-26 | 2003-05-26 | Sigma Tau Ind Farmaceuti | Uso della propionil l-carnitina o di un suo sale farmacologicamente accettabile per la preparazione di un medicamento per il trattamento del |
US20030235646A1 (en) * | 2002-03-15 | 2003-12-25 | Lonza Inc. | Method for improving quality of meat by supplementing pig diets and concentrates used therefor |
JP4539096B2 (ja) * | 2004-01-16 | 2010-09-08 | 日油株式会社 | 油性成分被覆l−カルニチン塩粉末およびその用途 |
US20050232911A1 (en) * | 2004-04-19 | 2005-10-20 | Schreiber Brian D | Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid |
JP2006111550A (ja) * | 2004-10-13 | 2006-04-27 | Nisshin Pharma Inc | カルニチン含有製品 |
CN100518537C (zh) * | 2006-01-13 | 2009-07-29 | 天津天隆农业科技有限公司 | 一种含有二十八烷醇和l-肉碱的水产饲料及其生产方法 |
CN101209975B (zh) * | 2006-12-29 | 2010-12-01 | 沈阳科硕营养科技有限公司 | 左旋肉碱富马酸钙及其制备方法与用途 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1153640A (en) * | 1967-04-10 | 1969-05-29 | Soc D Etudes Prod Chimique | A Carnitin Salt |
FR2529545B1 (fr) * | 1982-07-02 | 1985-05-31 | Sanofi Sa | Nouveaux sels de carnitine ainsi que leur procede de preparation |
DE3463261D1 (en) * | 1983-12-28 | 1987-05-27 | Sigma Tau Ind Farmaceuti | Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same |
CA2018137C (fr) * | 1989-06-14 | 2000-01-11 | Thomas Scholl | Citrate magnesique de l-carnitine |
US5073376A (en) * | 1989-12-22 | 1991-12-17 | Lonza Ltd. | Preparations containing l-carnitine |
IT1261688B (it) * | 1993-05-28 | 1996-05-29 | Avantgarde Spa | Uso di esteri sull'ossidrile della l-carnitina per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee. |
-
1997
- 1997-04-30 IT IT97RM000254A patent/IT1290600B1/it active IP Right Grant
-
1998
- 1998-04-08 HU HU0002198A patent/HUP0002198A3/hu unknown
- 1998-04-08 WO PCT/IT1998/000079 patent/WO1998049134A1/fr active IP Right Grant
- 1998-04-08 EP EP98917597A patent/EP0979224B1/fr not_active Expired - Lifetime
- 1998-04-08 JP JP54679098A patent/JP2001524106A/ja not_active Ceased
- 1998-04-08 CN CNB988046199A patent/CN1137088C/zh not_active Expired - Fee Related
- 1998-04-08 DK DK98917597T patent/DK0979224T3/da active
- 1998-04-08 KR KR1019997009928A patent/KR100556238B1/ko not_active IP Right Cessation
- 1998-04-08 DE DE69806590T patent/DE69806590T2/de not_active Expired - Lifetime
- 1998-04-08 SK SK1462-99A patent/SK283818B6/sk not_active IP Right Cessation
- 1998-04-08 IL IL13227598A patent/IL132275A0/xx active IP Right Grant
- 1998-04-08 US US09/402,649 patent/US6051608A/en not_active Expired - Fee Related
- 1998-04-08 AT AT98917597T patent/ATE220659T1/de not_active IP Right Cessation
- 1998-04-08 PT PT98917597T patent/PT979224E/pt unknown
- 1998-04-08 NZ NZ500536A patent/NZ500536A/en unknown
- 1998-04-08 ES ES98917597T patent/ES2179485T3/es not_active Expired - Lifetime
- 1998-04-08 CA CA002288287A patent/CA2288287C/fr not_active Expired - Fee Related
- 1998-04-08 BR BR9809368-1A patent/BR9809368A/pt active Search and Examination
- 1998-04-08 CZ CZ19993813A patent/CZ290159B6/cs not_active IP Right Cessation
- 1998-04-08 AU AU70776/98A patent/AU733008B2/en not_active Ceased
- 1998-04-08 PL PL98336530A patent/PL189602B1/pl not_active IP Right Cessation
-
1999
- 1999-10-07 IL IL132275A patent/IL132275A/en not_active IP Right Cessation
-
2000
- 2000-04-20 HK HK00102412A patent/HK1025559A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATE220659T1 (de) | 2002-08-15 |
US6051608A (en) | 2000-04-18 |
IL132275A (en) | 2006-08-01 |
HUP0002198A2 (hu) | 2000-11-28 |
CZ290159B6 (cs) | 2002-06-12 |
HK1025559A1 (en) | 2000-11-17 |
EP0979224A1 (fr) | 2000-02-16 |
JP2001524106A (ja) | 2001-11-27 |
KR20010020320A (ko) | 2001-03-15 |
PT979224E (pt) | 2002-12-31 |
DK0979224T3 (da) | 2002-09-02 |
CZ381399A3 (cs) | 2000-02-16 |
NZ500536A (en) | 2001-04-27 |
AU733008B2 (en) | 2001-05-03 |
IL132275A0 (en) | 2001-03-19 |
PL189602B1 (pl) | 2005-08-31 |
AU7077698A (en) | 1998-11-24 |
SK283818B6 (sk) | 2004-02-03 |
ES2179485T3 (es) | 2003-01-16 |
IT1290600B1 (it) | 1998-12-10 |
CN1253544A (zh) | 2000-05-17 |
BR9809368A (pt) | 2000-07-04 |
DE69806590D1 (de) | 2002-08-22 |
CN1137088C (zh) | 2004-02-04 |
ITRM970254A0 (it) | 1997-04-30 |
WO1998049134A1 (fr) | 1998-11-05 |
PL336530A1 (en) | 2000-07-03 |
HUP0002198A3 (en) | 2001-10-29 |
DE69806590T2 (de) | 2003-01-30 |
SK146299A3 (en) | 2000-09-12 |
CA2288287C (fr) | 2008-06-10 |
EP0979224B1 (fr) | 2002-07-17 |
ITRM970254A1 (it) | 1998-10-30 |
KR100556238B1 (ko) | 2006-03-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |