CA2287363A1 - Utilisation d'une composition pharmaceutique dans le traitement et/ou la prevention de l'ischemie - Google Patents

Utilisation d'une composition pharmaceutique dans le traitement et/ou la prevention de l'ischemie Download PDF

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Publication number
CA2287363A1
CA2287363A1 CA002287363A CA2287363A CA2287363A1 CA 2287363 A1 CA2287363 A1 CA 2287363A1 CA 002287363 A CA002287363 A CA 002287363A CA 2287363 A CA2287363 A CA 2287363A CA 2287363 A1 CA2287363 A1 CA 2287363A1
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CA
Canada
Prior art keywords
extracts
ischemia
patient
rutoside
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002287363A
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English (en)
Inventor
Carine Michiels
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Individual
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Individual
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Publication date
Application filed by Individual filed Critical Individual
Publication of CA2287363A1 publication Critical patent/CA2287363A1/fr
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention concerne l'utilisation d'une composition pharmaceutique comprenant un véhicule pharmaceutique adéquat et un composé actif choisi parmi le groupe constitué par les citroflavonoïdes, l'ail-rutoside, la troxérutine, la coumarine, la diosmine, les o-(-hydroxyéthyl) rutosides, les extraits de Mélilot et de rutoside, le tribénoside, l'hespéridine méthylchalcone, l'extrait de marron d'Inde, le naftazone, l'esculoside, l'aescine, les oligomères procyanidoliques, les extraits de ruscus et d'hespéridine méthylchalcone, les ruscosides, les extraits de petit houx et cassis, les extraits d'anthocyanodisiques de myrtilles, les principes actifs de ces composés et/ou mélange d'entre eux, agissant sur les complexes protéiniques de la membrane mitochondriale interne d'un patient, pour la préparation d'un médicament destiné au traitement et/ou à la prévention de l'ischémie et/ou des pathologies associées à l'ischémie ou à un déficit énergétique.
CA002287363A 1997-05-13 1998-05-12 Utilisation d'une composition pharmaceutique dans le traitement et/ou la prevention de l'ischemie Abandoned CA2287363A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BE9700415A BE1011151A3 (fr) 1997-05-13 1997-05-13 Utilisation d'une composition pharmaceutique dans le traitement et/ou la prevention de l'ischemie.
BE97/00,415 1997-05-13
PCT/BE1998/000067 WO1998051291A1 (fr) 1997-05-13 1998-05-12 Utilisation d'une composition pharmaceutique dans le traitement et/ou la prevention de l'ischemie

Publications (1)

Publication Number Publication Date
CA2287363A1 true CA2287363A1 (fr) 1998-11-19

Family

ID=3890512

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002287363A Abandoned CA2287363A1 (fr) 1997-05-13 1998-05-12 Utilisation d'une composition pharmaceutique dans le traitement et/ou la prevention de l'ischemie

Country Status (7)

Country Link
EP (1) EP0981339A1 (fr)
JP (1) JP2001526658A (fr)
AU (1) AU7327298A (fr)
BE (1) BE1011151A3 (fr)
CA (1) CA2287363A1 (fr)
NO (1) NO995500L (fr)
WO (1) WO1998051291A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD3987C2 (ro) * 2009-09-03 2010-07-31 Георге АНГЕЛИЧ Utilizare a Diosminei pentru tratamentul cirozei hepatice avansate asociate cu insuficienţă cardiacă
MD3986C2 (ro) * 2009-09-23 2010-07-31 Георге АНГЕЛИЧ Utilizare a Diosminei pentru tratamentul gastropatiilor portale în ciroza hepatică
MD4232C1 (ro) * 2012-11-08 2014-01-31 Георге АНГЕЛИЧ Remediu medicamentos pe bază de troxerutin şi carbazocrom pentru tratamentul cirozei hepatice avansate asociate cu insuficienţă cardiacă
MD4231C1 (ro) * 2012-11-08 2014-01-31 Георге АНГЕЛИЧ Remediu medicamentos pe bază de troxerutin şi carbazocrom pentru tratamentul gastropatiilor portale în ciroza hepatică

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2792203B1 (fr) * 1999-04-19 2003-05-16 Mu Laboratoire Nouvelle composition a base d'extraits vegetaux naturels, et son utilisation, notamment dans les domaines pharmaceutiques ou cosmetiques
FR2796552A1 (fr) 1999-07-21 2001-01-26 Centre Nat Rech Scient Nouvelle utilisation de derives de la beta-naphtoquinone et de leurs sels pour la fabrication de medicaments exercant un effet inhibiteur sur la liberation de glutamate dans le cerveau
FR2802425B1 (fr) * 1999-12-21 2003-09-26 Oreal Utilisation d'un extrait d'au moins un vegetal de la famille des ericaceae comme agent anti-glycation
EP1127572A3 (fr) * 2000-02-25 2003-05-02 Basf Aktiengesellschaft Utilisation de flavones dans le traitement de maladies induites par cyclooxygenase-2
FR2814950B1 (fr) 2000-10-05 2003-08-08 Oreal Utilisation d'au moins un extrait d'au moins un vegetal de la famille des ericaceae, dans des compositions destinees a traiter les signes cutanes du vieillissement
DE10122715A1 (de) * 2001-05-10 2002-11-21 Brench Ag Verwendung von Rutinen und Aescinen zur Behandlung aurikulärer Durchblutungsstörungen
DE10122714A1 (de) * 2001-05-10 2002-11-21 Brench Ag Verwendung von Rutinen und Aescinen zur Behandlung okulärer Durchblutungsstörungen
EP1382326A1 (fr) * 2002-07-17 2004-01-21 Cognis France S.A. Procédé pour protéger la peau contre le vieillissement
EP1382327A1 (fr) * 2002-07-17 2004-01-21 Cognis France S.A. Procédé de proteger la peau contre la vieillissement
FR2844716B1 (fr) * 2002-09-23 2008-11-21 Marcel Jacques Chicouri Nouvelles compositions pharmaceutiques destinees notamment a l'hygiene des pieds des diabetiques
JP4562365B2 (ja) * 2003-09-19 2010-10-13 株式会社ノエビア 健康増進用組成物
EP1550450A1 (fr) * 2003-12-29 2005-07-06 Boehringer Ingelheim International GmbH Traitement des insuffisances veineuses chroniques à l'aide d'un extrait de feuilles de vigne rouge et d'un agent améliorant la circulation sanguine
EP1588705A1 (fr) * 2004-04-21 2005-10-26 INTE:LIGAND Software-Entwicklungs und Consulting GmbH Utilisation de dérivés de la coumarine
EP1607006A1 (fr) * 2004-06-18 2005-12-21 Unilever N.V. Composition functionelle des baies
EP1959969A2 (fr) * 2005-07-01 2008-08-27 The Johns Hopkins University Compositions et procedes pour traiter ou prevenir des troubles associes au stress oxydatif
FR2904222A1 (fr) 2006-07-27 2008-02-01 Sod Conseils Rech Applic Utilisation d4extraits de ginkgo biloba pour le traitement de maladies mitochondriales
KR100880876B1 (ko) * 2007-04-11 2009-01-30 경상대학교산학협력단 검정콩 껍질로부터 추출한 안토시아닌을 함유하는 피판이나조직의 허혈-재관류 손상의 예방 또는 치료용 의약 조성물
DE102007033067A1 (de) * 2007-07-13 2009-01-15 Institut für Umweltmedizinische Forschung gGmbH Zubereitungen zur Verbesserung des Schutzes menschlicher Zellen, insbesondere Zellen der menschlichen Haut vor schädigenden Einflüssen durch oxidative Noxen und UV-Bestrahlung
EP2014276A1 (fr) 2007-06-20 2009-01-14 Cognis IP Management GmbH Compositions cosmétiques comportant de la sclaréolide et de la hespéridine méthyl chalcone
CN110585222B (zh) * 2019-10-12 2023-05-09 西南医科大学 七叶皂苷类化合物在制备药物中的应用
IT202000010924A1 (it) * 2020-05-13 2021-11-13 Neilos S R L “composizione per la prevenzione e il trattamento di patologie dell’apparato circolatorio e dei sintomi correlati”
CN112138015B (zh) * 2020-10-22 2022-08-05 合肥博思科创医药科技有限公司 三苄糖苷在治疗微循环障碍引起的皮肤疾病中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3623255A1 (de) * 1986-07-10 1988-01-21 Oxo Chemie Gmbh Pharmazeutisches mittel zur verhinderung oxidativer blutgefaess-schaedigungen
DE3808835A1 (de) * 1987-03-27 1988-10-06 Sandoz Ag Arzneimittel enthaltend eine mischung aus dihydroergotamin, etilefrin und troxerutin
FR2707495B1 (fr) * 1993-07-02 1995-09-01 Roussel Uclaf Nouvelle utilisation de dérivés de la béta-naphtoquinone ainsi que de leurs sels.
FR2726469B1 (fr) * 1994-11-08 1996-12-13 Adir Composition pharmaceutique pour l'administration orale de flavonoides

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD3987C2 (ro) * 2009-09-03 2010-07-31 Георге АНГЕЛИЧ Utilizare a Diosminei pentru tratamentul cirozei hepatice avansate asociate cu insuficienţă cardiacă
MD3986C2 (ro) * 2009-09-23 2010-07-31 Георге АНГЕЛИЧ Utilizare a Diosminei pentru tratamentul gastropatiilor portale în ciroza hepatică
MD4232C1 (ro) * 2012-11-08 2014-01-31 Георге АНГЕЛИЧ Remediu medicamentos pe bază de troxerutin şi carbazocrom pentru tratamentul cirozei hepatice avansate asociate cu insuficienţă cardiacă
MD4231C1 (ro) * 2012-11-08 2014-01-31 Георге АНГЕЛИЧ Remediu medicamentos pe bază de troxerutin şi carbazocrom pentru tratamentul gastropatiilor portale în ciroza hepatică

Also Published As

Publication number Publication date
NO995500D0 (no) 1999-11-10
WO1998051291A1 (fr) 1998-11-19
AU7327298A (en) 1998-12-08
EP0981339A1 (fr) 2000-03-01
BE1011151A3 (fr) 1999-05-04
NO995500L (no) 1999-11-10
JP2001526658A (ja) 2001-12-18

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