CA2277220A1 - Tablet for the controlled release of active agents - Google Patents
Tablet for the controlled release of active agents Download PDFInfo
- Publication number
- CA2277220A1 CA2277220A1 CA002277220A CA2277220A CA2277220A1 CA 2277220 A1 CA2277220 A1 CA 2277220A1 CA 002277220 A CA002277220 A CA 002277220A CA 2277220 A CA2277220 A CA 2277220A CA 2277220 A1 CA2277220 A1 CA 2277220A1
- Authority
- CA
- Canada
- Prior art keywords
- weight
- tablet according
- aqueous medium
- swelling
- polymeric material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000013543 active substance Substances 0.000 title claims abstract description 51
- 238000013270 controlled release Methods 0.000 title claims abstract description 10
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- 239000012792 core layer Substances 0.000 claims abstract description 53
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- 239000000463 material Substances 0.000 claims abstract description 47
- 230000008961 swelling Effects 0.000 claims abstract description 45
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- 238000000576 coating method Methods 0.000 claims abstract description 16
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- 229930195725 Mannitol Natural products 0.000 description 1
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- 229920002125 Sokalan® Polymers 0.000 description 1
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- YQEMORVAKMFKLG-UHFFFAOYSA-N glycerine monostearate Natural products CCCCCCCCCCCCCCCCCC(=O)OC(CO)CO YQEMORVAKMFKLG-UHFFFAOYSA-N 0.000 description 1
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- YRVIKLBSVVNSHF-JTQLQIEISA-N pozanicline Chemical compound CC1=NC=CC=C1OC[C@H]1NCCC1 YRVIKLBSVVNSHF-JTQLQIEISA-N 0.000 description 1
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- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
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- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78176197A | 1997-01-10 | 1997-01-10 | |
| US08/781,761 | 1997-01-10 | ||
| PCT/US1997/023358 WO1998030208A1 (en) | 1997-01-10 | 1997-12-18 | Tablet for the controlled release of active agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2277220A1 true CA2277220A1 (en) | 1998-07-16 |
Family
ID=25123834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002277220A Abandoned CA2277220A1 (en) | 1997-01-10 | 1997-12-18 | Tablet for the controlled release of active agents |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6033685A (enExample) |
| EP (1) | EP0951279A1 (enExample) |
| JP (1) | JP5170723B2 (enExample) |
| AR (1) | AR010875A1 (enExample) |
| AU (1) | AU5609998A (enExample) |
| CA (1) | CA2277220A1 (enExample) |
| WO (1) | WO1998030208A1 (enExample) |
| ZA (1) | ZA9880B (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE1011045A3 (fr) * | 1997-03-14 | 1999-04-06 | Ucb Sa | Compositions pharmaceutiques pour la liberation controlee de substances actives. |
| FR2772615B1 (fr) * | 1997-12-23 | 2002-06-14 | Lipha | Comprime multicouche pour la liberation instantanee puis prolongee de substances actives |
| GB9901688D0 (en) * | 1999-01-26 | 1999-03-17 | Unilever Plc | Detergent compositions |
| AR030557A1 (es) * | 2000-04-14 | 2003-08-27 | Jagotec Ag | Una tableta en multicapa de liberacion controlada y metodo de tratamiento |
| US6960357B2 (en) * | 2001-05-25 | 2005-11-01 | Mistral Pharma Inc. | Chemical delivery device |
| US7052706B2 (en) * | 2001-06-08 | 2006-05-30 | Nostrum Pharmaceuticals, Inc. | Control release formulation containing a hydrophobic material as the sustained release agent |
| US20030091630A1 (en) * | 2001-10-25 | 2003-05-15 | Jenny Louie-Helm | Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data |
| US20030104052A1 (en) * | 2001-10-25 | 2003-06-05 | Bret Berner | Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract |
| CA2409552A1 (en) * | 2001-10-25 | 2003-04-25 | Depomed, Inc. | Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract |
| US20030152622A1 (en) * | 2001-10-25 | 2003-08-14 | Jenny Louie-Helm | Formulation of an erodible, gastric retentive oral diuretic |
| US20030133982A1 (en) * | 2001-12-20 | 2003-07-17 | Heimlich John M. | Zero-order sustained release dosage forms and method of making same |
| ES2399880T3 (es) * | 2002-03-15 | 2013-04-04 | Cypress Bioscience, Inc. | Milnaciprán para el tratamiento del síndrome del intestino irritable |
| US20060003004A1 (en) * | 2002-10-25 | 2006-01-05 | Collegium Pharmaceutical, Inc. | Pulsatile release compositions of milnacipran |
| US20040132826A1 (en) * | 2002-10-25 | 2004-07-08 | Collegium Pharmaceutical, Inc. | Modified release compositions of milnacipran |
| JP2006510639A (ja) * | 2002-12-06 | 2006-03-30 | ユセベ ファルシム ソシエテ アノニム | エフレチリジン及びプソイドエフェドリンを含む錠剤 |
| WO2004067039A1 (en) * | 2003-01-28 | 2004-08-12 | Collegium Pharmaceutical, Inc. | Multiparticulate compositions of milnacipran for oral administration |
| CA2518442A1 (en) * | 2003-03-04 | 2004-09-16 | Nostrum Pharmaceuticals, Inc. | Control release formulation containing a hydrophobic material as the sustained release agent |
| SI1575565T1 (sl) * | 2003-08-08 | 2010-04-30 | Biovail Lab Int Srl | Tableta bupropion hidroklorida z modificiranim sprošŽŤanjem |
| WO2005065673A1 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Atomoxetine formulations |
| KR20070043806A (ko) * | 2004-07-29 | 2007-04-25 | 사노피-아벤티스 | ｐＨ에 매우 의존적인 용해도를 가지는 활성 성분의 제어방출을 위한 약제학적 다층 정제 |
| US20080248107A1 (en) * | 2005-08-24 | 2008-10-09 | Rubicon Research Pvt. Ltd. | Controlled Release Formulation |
| US8691272B2 (en) | 2005-12-30 | 2014-04-08 | Intelgenx Corp. | Multilayer tablet |
| JP4953673B2 (ja) * | 2006-03-22 | 2012-06-13 | リンテック株式会社 | 経口投与剤 |
| US20080107725A1 (en) * | 2006-10-13 | 2008-05-08 | Albano Antonio A | Pharmaceutical Solid Dosage Forms Comprising Amorphous Compounds Micro-Embedded in Ionic Water-Insoluble Polymers |
| KR100885029B1 (ko) * | 2007-02-07 | 2009-02-23 | 지엘팜텍 주식회사 | 경구투여용 서방성 삼중정제 |
| MX2010008861A (es) * | 2008-02-15 | 2011-02-22 | Sun Pharma Advanced Res Co Ltd | Tableta oral de liberacion controlada con efecto de liberacion masiva reducido. |
| US20100260842A1 (en) * | 2009-04-06 | 2010-10-14 | Rashmi Nair | Pseudoephedrine pharmaceutical formulations |
| WO2011016057A2 (en) * | 2009-08-05 | 2011-02-10 | Lupin Limited | Controlled release pharmaceutical compositions of milnacipran |
| WO2011032139A2 (en) * | 2009-09-14 | 2011-03-17 | Virginia Commonwealth University | Electrospun nerve guides for nerve regeneration designed to modulate nerve architecture |
| US20110136815A1 (en) | 2009-12-08 | 2011-06-09 | Horst Zerbe | Solid oral film dosage forms and methods for making same |
| US10610528B2 (en) | 2009-12-08 | 2020-04-07 | Intelgenx Corp. | Solid oral film dosage forms and methods for making same |
| WO2011078993A1 (en) * | 2009-12-21 | 2011-06-30 | Aptapharma, Inc. | Functionally-coated multilayer tablets |
| GB2479213B (en) | 2010-04-01 | 2013-07-10 | Theravida Inc | Pharmaceutical formulations for the treatment of overactive bladder |
| KR102600541B1 (ko) | 2016-01-20 | 2023-11-08 | 테라비다, 인코포레이티드 | 다한증을 치료하기 위한 방법 및 조성물 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL109293C (enExample) * | 1955-12-22 | |||
| JPS5839618A (ja) * | 1981-09-04 | 1983-03-08 | Chugai Pharmaceut Co Ltd | 持続性積層錠剤 |
| US4756911A (en) * | 1986-04-16 | 1988-07-12 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
| US5114719A (en) * | 1987-04-29 | 1992-05-19 | Sabel Bernhard A | Extended drug delivery of small, water-soluble molecules |
| EP0317780B1 (en) * | 1987-11-25 | 1992-05-20 | American Cyanamid Company | Sustained (controlled) release delivery system for substituted dihydropyridine calcium channel blockers |
| JPH04360826A (ja) * | 1991-06-07 | 1992-12-14 | Bayer Yakuhin Kk | 放出制御製剤 |
| FR2677886B1 (fr) * | 1991-06-18 | 1995-03-31 | Adir | Comprime matriciel permettant la liberation prolongee d'indapamide apres administration par voie orale. |
| DE69229881T2 (de) * | 1991-10-04 | 1999-12-09 | Yoshitomi Pharmaceutical Industries, Ltd. | Tablette mit verzögerter freisetzung |
| JPH0791500B2 (ja) * | 1991-10-25 | 1995-10-04 | 太田インキ製造株式会社 | 印刷インキ組成物 |
| IT1256393B (it) * | 1992-11-17 | 1995-12-04 | Inverni Della Beffa Spa | Forme matriciali multistrato per il rilascio controllato di principi attivi |
| IT1265240B1 (it) * | 1993-11-30 | 1996-10-31 | Ekita Investments Nv | Compressa farmaceutica a rilascio controllato, di forma lenticolare |
| CA2136810A1 (en) * | 1994-06-30 | 1995-12-31 | Franklin M. C. Chen | Absorbent structure including an adhesive |
-
1997
- 1997-12-18 EP EP97952511A patent/EP0951279A1/en not_active Withdrawn
- 1997-12-18 AU AU56099/98A patent/AU5609998A/en not_active Abandoned
- 1997-12-18 WO PCT/US1997/023358 patent/WO1998030208A1/en not_active Ceased
- 1997-12-18 CA CA002277220A patent/CA2277220A1/en not_active Abandoned
- 1997-12-18 JP JP53089798A patent/JP5170723B2/ja not_active Expired - Fee Related
-
1998
- 1998-01-06 ZA ZA9880A patent/ZA9880B/xx unknown
- 1998-01-09 AR ARP980100120A patent/AR010875A1/es unknown
- 1998-06-29 US US09/106,658 patent/US6033685A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998030208A1 (en) | 1998-07-16 |
| EP0951279A1 (en) | 1999-10-27 |
| JP2001508440A (ja) | 2001-06-26 |
| US6033685A (en) | 2000-03-07 |
| JP5170723B2 (ja) | 2013-03-27 |
| ZA9880B (en) | 1998-07-08 |
| AU5609998A (en) | 1998-08-03 |
| AR010875A1 (es) | 2000-07-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |