CA2275592C - Method for preparing a tetrahydropyridin derivative - Google Patents

Method for preparing a tetrahydropyridin derivative Download PDF

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Publication number
CA2275592C
CA2275592C CA002275592A CA2275592A CA2275592C CA 2275592 C CA2275592 C CA 2275592C CA 002275592 A CA002275592 A CA 002275592A CA 2275592 A CA2275592 A CA 2275592A CA 2275592 C CA2275592 C CA 2275592C
Authority
CA
Canada
Prior art keywords
trifluoromethylphenyl
tetrahydropyridine
base
salts
naphthalene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002275592A
Other languages
English (en)
French (fr)
Other versions
CA2275592A1 (en
Inventor
Michel Buj
Robert Filhol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Publication of CA2275592A1 publication Critical patent/CA2275592A1/en
Application granted granted Critical
Publication of CA2275592C publication Critical patent/CA2275592C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/093Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/16Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
CA002275592A 1996-12-23 1997-12-23 Method for preparing a tetrahydropyridin derivative Expired - Fee Related CA2275592C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR96/15906 1996-12-23
FR9615906A FR2757511B1 (fr) 1996-12-23 1996-12-23 Procede pour la preparation d'un derive de tetrahydropyridine
PCT/FR1997/002395 WO1998028273A1 (fr) 1996-12-23 1997-12-23 Procede pour la preparation d'un derive de tetrahydropyridine

Publications (2)

Publication Number Publication Date
CA2275592A1 CA2275592A1 (en) 1998-07-02
CA2275592C true CA2275592C (en) 2005-09-06

Family

ID=9499045

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002275592A Expired - Fee Related CA2275592C (en) 1996-12-23 1997-12-23 Method for preparing a tetrahydropyridin derivative

Country Status (18)

Country Link
US (1) US6118006A (no)
EP (1) EP0950052B1 (no)
JP (1) JP4234206B2 (no)
AT (1) ATE275548T1 (no)
AU (1) AU5668698A (no)
BR (1) BR9714080A (no)
CA (1) CA2275592C (no)
DE (1) DE69730615T2 (no)
DK (1) DK0950052T3 (no)
ES (1) ES2229398T3 (no)
FR (1) FR2757511B1 (no)
HK (1) HK1023120A1 (no)
HR (2) HRP970701B1 (no)
NO (2) NO313283B1 (no)
PT (1) PT950052E (no)
UY (1) UY24823A1 (no)
WO (1) WO1998028273A1 (no)
ZA (1) ZA9711583B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2598396B1 (de) 2010-07-30 2018-12-26 ATLAS ELEKTRONIK GmbH Verfahren und system zur aufklärung eines gebietes unter wasser

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910931A (en) * 1970-09-03 1975-10-07 Wyeth John & Brother Ltd 1-(Naphthylalkyl- or indenylalkyl)-piperidines
GB1392194A (en) * 1971-09-23 1975-04-30 Wyeth John & Brother Ltd Pyrrolidine derivatives
DE2862340D1 (en) * 1978-02-01 1983-11-24 Wellcome Found Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations thereof
FR2531707A1 (fr) * 1982-08-16 1984-02-17 Midy Spa Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques

Also Published As

Publication number Publication date
NO20022778D0 (no) 2002-06-11
HK1023120A1 (en) 2000-09-01
US6118006A (en) 2000-09-12
ES2229398T3 (es) 2005-04-16
DE69730615D1 (de) 2004-10-14
NO316069B1 (no) 2003-12-08
NO993078L (no) 1999-06-22
ZA9711583B (en) 1998-06-24
EP0950052B1 (fr) 2004-09-08
HRP970701A2 (en) 1998-10-31
DE69730615T2 (de) 2005-09-22
DK0950052T3 (da) 2005-01-10
WO1998028273A1 (fr) 1998-07-02
HRP970701B1 (en) 2002-04-30
NO993078D0 (no) 1999-06-22
FR2757511B1 (fr) 2001-05-04
JP2001507014A (ja) 2001-05-29
AU5668698A (en) 1998-07-17
UY24823A1 (es) 1998-04-21
EP0950052A1 (fr) 1999-10-20
HRP970700A2 (en) 1998-10-31
PT950052E (pt) 2004-12-31
NO20022778L (no) 1999-06-22
FR2757511A1 (fr) 1998-06-26
CA2275592A1 (en) 1998-07-02
NO313283B1 (no) 2002-09-09
ATE275548T1 (de) 2004-09-15
BR9714080A (pt) 2000-05-02
JP4234206B2 (ja) 2009-03-04

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Effective date: 20121224