CA2269646A1 - Proteines mediatrices du diabete et leurs utilisations therapeutiques - Google Patents
Proteines mediatrices du diabete et leurs utilisations therapeutiques Download PDFInfo
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- CA2269646A1 CA2269646A1 CA002269646A CA2269646A CA2269646A1 CA 2269646 A1 CA2269646 A1 CA 2269646A1 CA 002269646 A CA002269646 A CA 002269646A CA 2269646 A CA2269646 A CA 2269646A CA 2269646 A1 CA2269646 A1 CA 2269646A1
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- 238000012800 visualization Methods 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 238000011706 wistar kyoto rat Methods 0.000 description 1
- BPICBUSOMSTKRF-UHFFFAOYSA-N xylazine Chemical compound CC1=CC=CC(C)=C1NC1=NCCCS1 BPICBUSOMSTKRF-UHFFFAOYSA-N 0.000 description 1
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/0002—Inspection of images, e.g. flaw detection
- G06T7/0012—Biomedical image inspection
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0306—Animal model for genetic diseases
- A01K2267/0325—Animal model for autoimmune diseases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2550/00—Electrophoretic profiling, e.g. for proteome analysis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Environmental Sciences (AREA)
- Hematology (AREA)
- Radiology & Medical Imaging (AREA)
- Biodiversity & Conservation Biology (AREA)
- Plant Pathology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Medical Informatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Quality & Reliability (AREA)
- Computer Vision & Pattern Recognition (AREA)
- General Physics & Mathematics (AREA)
- Theoretical Computer Science (AREA)
- Cell Biology (AREA)
- Animal Husbandry (AREA)
Abstract
L'invention concerne des protéines médiatrices du diabète, protectrices et néfastes, les polynucléotides codant pour lesdites protéines, des animaux transgéniques exprimant une protéine médiatrice du diabète, des méthodes de criblage de médicaments qui permettent d'identifier un composé test capable de modifier l'expression desdites protéines, ainsi que des méthodes qui permettent de prévenir ou d'améliorer le diabète en administrant un composé capable de modifier l'expression d'une protéine médiatrice du diabète.
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2932496P | 1996-10-25 | 1996-10-25 | |
US60/029,324 | 1996-10-25 | ||
US3018696P | 1996-11-05 | 1996-11-05 | |
US3008896P | 1996-11-05 | 1996-11-05 | |
US60/030,186 | 1996-11-05 | ||
US60/030,088 | 1996-11-05 | ||
US89709897A | 1997-07-18 | 1997-07-18 | |
US08/897,098 | 1997-07-18 | ||
PCT/IB1997/001627 WO1998020124A2 (fr) | 1996-10-25 | 1997-10-24 | Proteines mediatrices du diabete et leurs utilisations therapeutiques |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2269646A1 true CA2269646A1 (fr) | 1998-05-14 |
Family
ID=27487746
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002269646A Abandoned CA2269646A1 (fr) | 1996-10-25 | 1997-10-24 | Proteines mediatrices du diabete et leurs utilisations therapeutiques |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0934409A2 (fr) |
JP (2) | JP2002504806A (fr) |
AU (1) | AU5407098A (fr) |
CA (1) | CA2269646A1 (fr) |
WO (1) | WO1998020124A2 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000024422A1 (fr) * | 1998-10-27 | 2000-05-04 | Suntory Limited | Procede de production de regulateurs glycolytiques du metabolisme |
JP2002534088A (ja) * | 1999-01-07 | 2002-10-15 | インサイト・ファーマスーティカルズ・インコーポレイテッド | インスリン合成遺伝子 |
AU773329B2 (en) * | 1999-05-14 | 2004-05-20 | Proteomedica Ab | Materials and methods relating to disease diagnosis |
EP1402257B1 (fr) * | 2001-05-29 | 2009-01-21 | Pride Proteomics A/S | Proteines utiles dans l'analyse proteomique du diabete |
EP1430155A2 (fr) * | 2001-09-05 | 2004-06-23 | Pride Proteomics A/S | Proteines impliquees dans le diabete de type 2 |
EP2071338A3 (fr) * | 2002-03-20 | 2009-07-22 | Pride Proteomics A/S | Protéines liées au diabète humain |
-
1997
- 1997-10-24 EP EP97947839A patent/EP0934409A2/fr not_active Withdrawn
- 1997-10-24 AU AU54070/98A patent/AU5407098A/en not_active Abandoned
- 1997-10-24 WO PCT/IB1997/001627 patent/WO1998020124A2/fr not_active Application Discontinuation
- 1997-10-24 JP JP52118298A patent/JP2002504806A/ja not_active Withdrawn
- 1997-10-24 CA CA002269646A patent/CA2269646A1/fr not_active Abandoned
-
2008
- 2008-02-21 JP JP2008040600A patent/JP2008195721A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2002504806A (ja) | 2002-02-12 |
EP0934409A2 (fr) | 1999-08-11 |
WO1998020124A2 (fr) | 1998-05-14 |
WO1998020124A3 (fr) | 1998-10-08 |
AU5407098A (en) | 1998-05-29 |
JP2008195721A (ja) | 2008-08-28 |
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