AU5407098A - Diabetes-mediating proteins and therapeutic uses thereof - Google Patents

Diabetes-mediating proteins and therapeutic uses thereof

Info

Publication number
AU5407098A
AU5407098A AU54070/98A AU5407098A AU5407098A AU 5407098 A AU5407098 A AU 5407098A AU 54070/98 A AU54070/98 A AU 54070/98A AU 5407098 A AU5407098 A AU 5407098A AU 5407098 A AU5407098 A AU 5407098A
Authority
AU
Australia
Prior art keywords
diabetes
protein
expression
mediating
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU54070/98A
Other languages
English (en)
Inventor
Henrik U. Andersen
Ulla Bjerre Christensen
Stephen J. Fey
Allan E Karlsen
Peter Mose Larsen
Jorn Nerup
Flemming Pociot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU5407098A publication Critical patent/AU5407098A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0271Chimeric vertebrates, e.g. comprising exogenous cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • A01K2267/0306Animal model for genetic diseases
    • A01K2267/0325Animal model for autoimmune diseases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/008Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2550/00Electrophoretic profiling, e.g. for proteome analysis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Environmental Sciences (AREA)
  • Hematology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Quality & Reliability (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Cell Biology (AREA)
  • Animal Husbandry (AREA)
AU54070/98A 1996-10-25 1997-10-24 Diabetes-mediating proteins and therapeutic uses thereof Abandoned AU5407098A (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US2932496P 1996-10-25 1996-10-25
US60029324 1996-10-25
US3018696P 1996-11-05 1996-11-05
US3008896P 1996-11-05 1996-11-05
US60030186 1996-11-05
US60030088 1996-11-05
US89709897A 1997-07-18 1997-07-18
US08897098 1997-07-18
PCT/IB1997/001627 WO1998020124A2 (fr) 1996-10-25 1997-10-24 Proteines mediatrices du diabete et leurs utilisations therapeutiques

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU15577/02A Division AU1557702A (en) 1996-10-25 2002-02-12 Diabetes-mediating proteins and therapeutic uses thereof

Publications (1)

Publication Number Publication Date
AU5407098A true AU5407098A (en) 1998-05-29

Family

ID=27487746

Family Applications (1)

Application Number Title Priority Date Filing Date
AU54070/98A Abandoned AU5407098A (en) 1996-10-25 1997-10-24 Diabetes-mediating proteins and therapeutic uses thereof

Country Status (5)

Country Link
EP (1) EP0934409A2 (fr)
JP (2) JP2002504806A (fr)
AU (1) AU5407098A (fr)
CA (1) CA2269646A1 (fr)
WO (1) WO1998020124A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000024422A1 (fr) * 1998-10-27 2000-05-04 Suntory Limited Procede de production de regulateurs glycolytiques du metabolisme
JP2002534088A (ja) * 1999-01-07 2002-10-15 インサイト・ファーマスーティカルズ・インコーポレイテッド インスリン合成遺伝子
AU773329B2 (en) * 1999-05-14 2004-05-20 Proteomedica Ab Materials and methods relating to disease diagnosis
EP1402257B1 (fr) * 2001-05-29 2009-01-21 Pride Proteomics A/S Proteines utiles dans l'analyse proteomique du diabete
EP1430155A2 (fr) * 2001-09-05 2004-06-23 Pride Proteomics A/S Proteines impliquees dans le diabete de type 2
EP2071338A3 (fr) * 2002-03-20 2009-07-22 Pride Proteomics A/S Protéines liées au diabète humain

Also Published As

Publication number Publication date
JP2002504806A (ja) 2002-02-12
CA2269646A1 (fr) 1998-05-14
EP0934409A2 (fr) 1999-08-11
WO1998020124A2 (fr) 1998-05-14
WO1998020124A3 (fr) 1998-10-08
JP2008195721A (ja) 2008-08-28

Similar Documents

Publication Publication Date Title
US7531323B2 (en) Diabetes-mediating proteins and therapeutic uses thereof
Rich et al. Effect of deleting the R domain on CFTR-generated chloride channels
US6777388B1 (en) Leptin-related peptides
CZ20032706A3 (cs) Izolovaný polypeptid a nukleová kyselina a farmaceutický přípravek, který je obsahuje, pro diagnostiku, prevenci a léčení degenerativních onemocnění sitníce
JP2008195721A (ja) 糖尿病媒介タンパク質およびその治療的使用
Saegusa et al. Decreased basal mucus secretion by Slp2‐a‐deficient gastric surface mucous cells
US20050031605A1 (en) Compositions and methods of treating diabetes
Fang et al. Murine FLIP transgene expressed on thyroid epithelial cells promotes resolution of granulomatous experimental autoimmune thyroiditis in DBA/1 mice
RU2409590C2 (ru) Новый пептид, участвующий в энергетическом гомеостазе
Han et al. AUTHOR COPY ONLY
US9109043B2 (en) Screening method for antidiabetic agent using newly identified insulin secretion regulation factor
CN110812470A (zh) 用于代谢调节的方法和组合物
EP1609862A1 (fr) Protéines médiatrices de diabetes et leurs utilisations thérapeutiques
AU1557702A (en) Diabetes-mediating proteins and therapeutic uses thereof
EP1163335B1 (fr) MATERIAUX ET PROCEDES RELATIFS A LA MODULATION DE L'EXPRESSION DE p66
CN100360665C (zh) 华支睾吸虫i类醛脱氢酶,其编码核酸及其应用
WO2005094887A1 (fr) AGENT DE POTENTIALISATION DE L'EXPRESSION DE sFRP
DE60024862T2 (de) "insulinabhängiges sequenz dna bindendes protein-1" (irsdbp-1), dafür kodierendes gen und ihre verwendungen
US20050048602A1 (en) Kidney repairing factor
Levasseur Role of DHS in translation control of islet β-cell replication during high fat induced obesity and glucose intolerance
US20040235769A1 (en) Anti-tumor effects of prostage Carcinoma Tumor Antigen-1
CN116411061A (zh) E3连接酶rnf99在负向调控tlr介导的炎症免疫反应中的应用
CN100374559C (zh) 华支睾吸虫蛋白酶体亚单位c3,其编码核酸及其应用
Preston Ferrer Functional analysis of the potassium channel beta subunit KCNE3
Ferrer Functional analysis of the potassium channel beta subunit KCNE3

Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted