CA2266749C - The use of modular oligonucleotides as probes or primers in nucleic acid based assay - Google Patents

The use of modular oligonucleotides as probes or primers in nucleic acid based assay Download PDF

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Publication number
CA2266749C
CA2266749C CA002266749A CA2266749A CA2266749C CA 2266749 C CA2266749 C CA 2266749C CA 002266749 A CA002266749 A CA 002266749A CA 2266749 A CA2266749 A CA 2266749A CA 2266749 C CA2266749 C CA 2266749C
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CA
Canada
Prior art keywords
oligonucleotide
nucleic acid
capture
modular
module
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002266749A
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English (en)
French (fr)
Other versions
CA2266749A1 (en
Inventor
Joakim Lundeberg
Mathias Uhlen
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Invitrogen Dynal AS
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Publication date
Application filed by Invitrogen Dynal AS filed Critical Invitrogen Dynal AS
Publication of CA2266749A1 publication Critical patent/CA2266749A1/en
Application granted granted Critical
Publication of CA2266749C publication Critical patent/CA2266749C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Seeds, Soups, And Other Foods (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Semiconductor Lasers (AREA)
CA002266749A 1996-09-26 1997-09-26 The use of modular oligonucleotides as probes or primers in nucleic acid based assay Expired - Fee Related CA2266749C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9620075.3 1996-09-26
GBGB9620075.3A GB9620075D0 (en) 1996-09-26 1996-09-26 Method
PCT/GB1997/002629 WO1998013522A1 (en) 1996-09-26 1997-09-26 The use of modular oligonucleotides as probes or primers in nucleic acid based assay

Publications (2)

Publication Number Publication Date
CA2266749A1 CA2266749A1 (en) 1998-04-02
CA2266749C true CA2266749C (en) 2009-11-10

Family

ID=10800518

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002266749A Expired - Fee Related CA2266749C (en) 1996-09-26 1997-09-26 The use of modular oligonucleotides as probes or primers in nucleic acid based assay

Country Status (10)

Country Link
US (1) US6482592B1 (https=)
EP (1) EP0928342B1 (https=)
JP (1) JP2001501470A (https=)
AT (1) ATE288499T1 (https=)
AU (1) AU743820B2 (https=)
CA (1) CA2266749C (https=)
DE (1) DE69732419T2 (https=)
ES (1) ES2234031T3 (https=)
GB (1) GB9620075D0 (https=)
WO (1) WO1998013522A1 (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9620075D0 (en) 1996-09-26 1996-11-13 Dynal As Method
US5888778A (en) * 1997-06-16 1999-03-30 Exact Laboratories, Inc. High-throughput screening method for identification of genetic mutations or disease-causing microorganisms using segmented primers
GB9820185D0 (en) * 1998-09-15 1998-11-11 Dynal As Method
AU773108B2 (en) * 1998-09-15 2004-05-13 Dynal Asa Method of isolation primer extension products with modular oligonucleotides
US20010031467A1 (en) * 1999-12-10 2001-10-18 Johannes Dapprich Method for selectively isolating a nucleic acid
US20040161764A1 (en) * 2001-03-15 2004-08-19 Jean Gabert Preparation of calibrants and use thereof in the quantification of nucleotide sequences of interest
AU2004254367B2 (en) * 2003-06-27 2008-06-19 Nanosphere, Inc. Bio-barcode based detection of target analytes
US20050095627A1 (en) * 2003-09-03 2005-05-05 The Salk Institute For Biological Studies Multiple antigen detection assays and reagents
EP1784508B1 (en) * 2004-08-09 2012-10-03 Generation Biotech, LLC Method for nucleic acid isolation and amplification
WO2006047787A2 (en) 2004-10-27 2006-05-04 Exact Sciences Corporation Method for monitoring disease progression or recurrence
US9777314B2 (en) 2005-04-21 2017-10-03 Esoterix Genetic Laboratories, Llc Analysis of heterogeneous nucleic acid samples
US20090263798A1 (en) * 2006-05-15 2009-10-22 Generation Biotech, Llc Method For Identification Of Novel Physical Linkage Of Genomic Sequences
EP1903117A1 (en) * 2006-09-22 2008-03-26 Veterinärmedizinische Universität Wien Methods for the detection of mutations by means of primers that hybridize contiguously
US8790916B2 (en) 2009-05-14 2014-07-29 Genestream, Inc. Microfluidic method and system for isolating particles from biological fluid
US8747084B2 (en) 2010-07-21 2014-06-10 Aperia Technologies, Inc. Peristaltic pump
EP2809784A4 (en) * 2012-01-31 2015-07-15 Advanced Liquid Logic Inc AMPLIFICATION SPREADERS AND PROBES FOR DETECTING HIV-1
US9862995B2 (en) * 2012-03-13 2018-01-09 Abhijit Ajit Patel Measurement of nucleic acid variants using highly-multiplexed error-suppressed deep sequencing
US9222473B2 (en) 2012-03-20 2015-12-29 Aperia Technologies, Inc. Passive pressure regulation mechanism
US9604157B2 (en) 2013-03-12 2017-03-28 Aperia Technologies, Inc. Pump with water management
US10245908B2 (en) 2016-09-06 2019-04-02 Aperia Technologies, Inc. System for tire inflation
US10144254B2 (en) 2013-03-12 2018-12-04 Aperia Technologies, Inc. Tire inflation system
US11453258B2 (en) 2013-03-12 2022-09-27 Aperia Technologies, Inc. System for tire inflation
ITUA20163413A1 (it) * 2016-05-13 2017-11-13 Fondazione St Italiano Tecnologia Reazione di amplificazione di acidi nucleici con primer cooperativi.
US10406869B2 (en) 2017-11-10 2019-09-10 Aperia Technologies, Inc. Inflation system
US11642920B2 (en) 2018-11-27 2023-05-09 Aperia Technologies, Inc. Hub-integrated inflation system
US12442364B2 (en) 2023-12-11 2025-10-14 Aperia Technologies, Inc. Two-stage pump and method of operation

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5149625A (en) 1987-08-11 1992-09-22 President And Fellows Of Harvard College Multiplex analysis of DNA
US5030557A (en) 1987-11-24 1991-07-09 Ml Technology Venture Means and method for enhancing nucleic acid hybridization
US4988617A (en) * 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
EP0436547B1 (en) * 1988-05-10 1994-11-30 E.I. Du Pont De Nemours And Company Process for rapid nucleic acid detection
JPH04500316A (ja) * 1989-05-24 1992-01-23 ジーン―トラック・システムス 淋菌を検出するための核酸プローブ
FR2663040B1 (fr) * 1990-06-11 1995-09-15 Bio Merieux Procede de detection d'une sequence nucleotidique selon la technique d'hybridation sandwich.
JPH0484899A (ja) * 1990-07-26 1992-03-18 Tosoh Corp 核酸測定法
US5627032A (en) * 1990-12-24 1997-05-06 Ulanovsky; Levy Composite primers for nucleic acids
US5428145A (en) 1991-08-09 1995-06-27 Immuno Japan, Inc. Non-A, non-B, hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems
US5387510A (en) 1991-10-02 1995-02-07 Eastman Kodak Company Detection of amplified nucleic acid using secondary capture oligonucleotides and test kit
GB9207598D0 (en) 1992-04-03 1992-05-20 Dynal As Method of sequencing double stranded dna
JP3408564B2 (ja) * 1992-04-30 2003-05-19 メディカル リサーチ カウンスル 結核菌中のイソニアジド抵抗性の迅速検出
US5547843A (en) * 1992-07-17 1996-08-20 Associated Universities, Inc. Method for promoting specific alignment of short oligonucleotides on nucleic acids
JP3454847B2 (ja) * 1992-08-26 2003-10-06 株式会社東芝 ハイブリダイゼーション法
CA2119701A1 (en) * 1993-04-16 1994-10-17 Colleen M. Nycz Nucleic acid assay procedure
JP3746083B2 (ja) * 1993-05-28 2006-02-15 日本製粉株式会社 隣接する２種の核酸プローブを用いたｒｎａの検出方法
EP0730662A4 (en) 1993-09-10 1999-11-24 Genevue Inc OPTICAL DETECTION OF THE POSITION OF OLIGONUCLEOTIDES ON LARGE DNA MOLECULES
WO1996013590A2 (en) * 1994-10-21 1996-05-09 Innogenetics N.V. New sequences of hepatitis c virus genotypes and their use as prophylactic, therapeutic and diagnostic agents
US5731153A (en) * 1996-08-26 1998-03-24 The Regents Of The University Of California Identification of random nucleic acid sequence aberrations using dual capture probes which hybridize to different chromosome regions
US5908745A (en) * 1996-01-16 1999-06-01 University Of Chicago Use of continuous/contiguous stacking hybridization as a diagnostic tool
GB9620075D0 (en) 1996-09-26 1996-11-13 Dynal As Method
US6124092A (en) 1996-10-04 2000-09-26 The Perkin-Elmer Corporation Multiplex polynucleotide capture methods and compositions
GB9820185D0 (en) * 1998-09-15 1998-11-11 Dynal As Method

Also Published As

Publication number Publication date
EP0928342B1 (en) 2005-02-02
US6482592B1 (en) 2002-11-19
DE69732419T2 (de) 2006-04-06
AU743820B2 (en) 2002-02-07
AU4391797A (en) 1998-04-17
EP0928342A1 (en) 1999-07-14
JP2001501470A (ja) 2001-02-06
WO1998013522A1 (en) 1998-04-02
DE69732419D1 (de) 2005-03-10
ES2234031T3 (es) 2005-06-16
CA2266749A1 (en) 1998-04-02
GB9620075D0 (en) 1996-11-13
ATE288499T1 (de) 2005-02-15

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