CA2265915C - Cxcr3 chemokine receptor, antibodies, nucleic acids, and methods of use - Google Patents
Cxcr3 chemokine receptor, antibodies, nucleic acids, and methods of use Download PDFInfo
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- CA2265915C CA2265915C CA2265915A CA2265915A CA2265915C CA 2265915 C CA2265915 C CA 2265915C CA 2265915 A CA2265915 A CA 2265915A CA 2265915 A CA2265915 A CA 2265915A CA 2265915 C CA2265915 C CA 2265915C
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/642—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a cytokine, e.g. IL2, chemokine, growth factors or interferons being the inactive part of the conjugate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
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- Toxicology (AREA)
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- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/709,838 | 1996-09-10 | ||
| US08/709,838 US6140064A (en) | 1996-09-10 | 1996-09-10 | Method of detecting or identifying ligands, inhibitors or promoters of CXC chemokine receptor 3 |
| US08/829,839 US6184358B1 (en) | 1996-09-10 | 1997-03-31 | IP-10/Mig receptor designated CXCR3, antibodies, nucleic acids, and methods of use therefor |
| US08/829,839 | 1997-03-31 | ||
| PCT/US1997/015915 WO1998011218A1 (en) | 1996-09-10 | 1997-09-10 | Cxcr3 chemokine receptor, antibodies, nucleic acids, and methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2265915A1 CA2265915A1 (en) | 1998-03-19 |
| CA2265915C true CA2265915C (en) | 2012-11-20 |
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| CA2265915A Expired - Fee Related CA2265915C (en) | 1996-09-10 | 1997-09-10 | Cxcr3 chemokine receptor, antibodies, nucleic acids, and methods of use |
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| JP (1) | JP4502408B2 (enExample) |
| AT (1) | ATE360689T1 (enExample) |
| AU (1) | AU734090B2 (enExample) |
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| DE (1) | DE69737656T2 (enExample) |
| ES (1) | ES2288305T3 (enExample) |
| WO (1) | WO1998011218A1 (enExample) |
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| US6025154A (en) | 1995-06-06 | 2000-02-15 | Human Genome Sciences, Inc. | Polynucleotides encoding human G-protein chemokine receptor HDGNR10 |
| US7888466B2 (en) | 1996-01-11 | 2011-02-15 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor HSATU68 |
| US6903194B1 (en) | 1996-09-26 | 2005-06-07 | Chungai Seiyaku Kabushiki Kaisha | Antibody against human parathormone related peptides |
| SE9801098D0 (sv) * | 1998-03-30 | 1998-03-30 | Astra Pharma Prod | Receptors |
| WO1999056532A1 (en) * | 1998-05-07 | 1999-11-11 | William Douglas Mckee | Valve assembly |
| US6171590B1 (en) * | 1998-09-30 | 2001-01-09 | Corixa Corporation | Chemokine receptor peptide for inducing an immune response |
| EP1127126B1 (en) * | 1998-11-06 | 2006-10-18 | Bayer HealthCare AG | G-protein coupled receptors, homologous to ebv-induced gpcr 2 (ebi-2). methods to seek for ligands thereof |
| US6329159B1 (en) * | 1999-03-11 | 2001-12-11 | Millennium Pharmaceuticals, Inc. | Anti-GPR-9-6 antibodies and methods of identifying agents which modulate GPR-9-6 function |
| US6358697B2 (en) | 1999-04-21 | 2002-03-19 | Children's Hospital Medical Center | Intracellular pharmaceutical targeting |
| ATE342979T1 (de) | 1999-08-03 | 2006-11-15 | Millennium Pharm Inc | 15571, ein neues gpcr-ähnliches molekül der secretin-ähnlichen familie und dessen verwendungen |
| MXPA02005199A (es) * | 1999-11-24 | 2002-11-07 | Schering Corp | Metodos para inhibir metastasis. |
| US6949243B1 (en) | 1999-11-24 | 2005-09-27 | Schering Corporation | Methods of inhibiting metastasis |
| AU2001249546A1 (en) * | 2000-03-27 | 2001-10-08 | Corixa Corporation | Methods for treating disease with antibodies to cxcr3 |
| EP1987842A1 (en) | 2000-04-28 | 2008-11-05 | Chugai Seiyaku Kabushiki Kaisha | Cell proliferation inhibitor |
| US7052676B2 (en) | 2000-09-26 | 2006-05-30 | The Regents Of The University Of Michigan | Methods for inhibition of HIV replication using a small molecule inhibitor |
| US7175988B2 (en) | 2001-02-09 | 2007-02-13 | Human Genome Sciences, Inc. | Human G-protein Chemokine Receptor (CCR5) HDGNR10 |
| CA2452544A1 (en) * | 2001-07-12 | 2003-01-23 | The Regents Of The University Of California | Method for treating secondary tissue degeneration associated with central nervous system injury |
| US7253007B2 (en) | 2001-11-30 | 2007-08-07 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
| US7871619B2 (en) | 2001-11-30 | 2011-01-18 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
| US7413866B2 (en) | 2001-11-30 | 2008-08-19 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
| US7442512B2 (en) | 2001-11-30 | 2008-10-28 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
| US7393934B2 (en) | 2001-12-21 | 2008-07-01 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor (CCR5) HDGNR10 |
| WO2003072134A1 (fr) * | 2002-02-28 | 2003-09-04 | Kyowa Hakko Kogyo Co., Ltd. | Diagnostics et therapeutiques pour la pneumonie interstitielle |
| US20050119174A1 (en) * | 2002-04-03 | 2005-06-02 | Sumitomo Pharmaceuticals Co. Ltd. | Novel blood sugar controller and method of screening the same |
| EP2399903A1 (en) | 2002-05-24 | 2011-12-28 | Millennium Pharmaceuticals, Inc. | Ccr9 inhibitors and methods of use thereof |
| US7227035B2 (en) | 2002-11-18 | 2007-06-05 | Chemocentryx | Bis-aryl sulfonamides |
| US7420055B2 (en) | 2002-11-18 | 2008-09-02 | Chemocentryx, Inc. | Aryl sulfonamides |
| PT1562940E (pt) | 2002-11-18 | 2007-07-23 | Chemocentryx Inc | Sulfonamidas de arilo. |
| US7741519B2 (en) | 2007-04-23 | 2010-06-22 | Chemocentryx, Inc. | Bis-aryl sulfonamides |
| DE60327106D1 (de) | 2002-12-20 | 2009-05-20 | Chemocentryx Inc | Inhibitoren der bindungder chemokine i-tac bzw. sdf-1 an den ccxckr2-rezeptor |
| US7834155B2 (en) | 2003-07-21 | 2010-11-16 | Immunogen Inc. | CA6 antigen-specific cytotoxic conjugate and methods of using the same |
| US7405275B2 (en) | 2003-09-24 | 2008-07-29 | Millennium Pharmaceuticals, Inc. | Antibodies which bind human CXCR3 |
| AU2005219322B2 (en) * | 2004-03-09 | 2008-09-18 | Kyoto University | Pharmaceutical Composition Comprising CXCR3 Inhibitor |
| CA2559809A1 (en) | 2004-03-12 | 2005-11-10 | Human Genome Sciences, Inc. | Antibodies against human g-protein chemokine receptor (ccr5) hdgnr10 |
| US7622583B2 (en) | 2005-01-14 | 2009-11-24 | Chemocentryx, Inc. | Heteroaryl sulfonamides and CCR2 |
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- 1997-09-10 JP JP51377198A patent/JP4502408B2/ja not_active Expired - Fee Related
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- 1997-09-10 EP EP97940941A patent/EP0925358B1/en not_active Expired - Lifetime
- 1997-09-10 CA CA2265915A patent/CA2265915C/en not_active Expired - Fee Related
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| ES2288305T3 (es) | 2008-01-01 |
| ATE360689T1 (de) | 2007-05-15 |
| CA2265915A1 (en) | 1998-03-19 |
| JP2002513388A (ja) | 2002-05-08 |
| WO1998011218A1 (en) | 1998-03-19 |
| DE69737656T2 (de) | 2008-01-03 |
| AU734090B2 (en) | 2001-06-07 |
| DE69737656D1 (de) | 2007-06-06 |
| JP4502408B2 (ja) | 2010-07-14 |
| AU4260897A (en) | 1998-04-02 |
| EP0925358A1 (en) | 1999-06-30 |
| EP0925358B1 (en) | 2007-04-25 |
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