ATE360689T1 - Cxcr3 chemokine rezeptor, antikoerper, nukleinsaeure und deren verfahren zur anwendung - Google Patents
Cxcr3 chemokine rezeptor, antikoerper, nukleinsaeure und deren verfahren zur anwendungInfo
- Publication number
- ATE360689T1 ATE360689T1 AT97940941T AT97940941T ATE360689T1 AT E360689 T1 ATE360689 T1 AT E360689T1 AT 97940941 T AT97940941 T AT 97940941T AT 97940941 T AT97940941 T AT 97940941T AT E360689 T1 ATE360689 T1 AT E360689T1
- Authority
- AT
- Austria
- Prior art keywords
- chemokine receptor
- antibodies
- nucleic acid
- mig
- receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/642—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a cytokine, e.g. IL2, chemokine, growth factors or interferons being the inactive part of the conjugate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/709,838 US6140064A (en) | 1996-09-10 | 1996-09-10 | Method of detecting or identifying ligands, inhibitors or promoters of CXC chemokine receptor 3 |
US08/829,839 US6184358B1 (en) | 1996-09-10 | 1997-03-31 | IP-10/Mig receptor designated CXCR3, antibodies, nucleic acids, and methods of use therefor |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE360689T1 true ATE360689T1 (de) | 2007-05-15 |
Family
ID=27108320
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97940941T ATE360689T1 (de) | 1996-09-10 | 1997-09-10 | Cxcr3 chemokine rezeptor, antikoerper, nukleinsaeure und deren verfahren zur anwendung |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0925358B1 (de) |
JP (1) | JP4502408B2 (de) |
AT (1) | ATE360689T1 (de) |
AU (1) | AU734090B2 (de) |
CA (1) | CA2265915C (de) |
DE (1) | DE69737656T2 (de) |
ES (1) | ES2288305T3 (de) |
WO (1) | WO1998011218A1 (de) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6025154A (en) | 1995-06-06 | 2000-02-15 | Human Genome Sciences, Inc. | Polynucleotides encoding human G-protein chemokine receptor HDGNR10 |
US7888466B2 (en) | 1996-01-11 | 2011-02-15 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor HSATU68 |
BR9713294A (pt) | 1996-09-26 | 2000-10-17 | Chugai Pharmaceutical Co Ltd | "anticorpos contra proteìna relacionada a hormÈnio de paratiróide humano" |
SE9801098D0 (sv) * | 1998-03-30 | 1998-03-30 | Astra Pharma Prod | Receptors |
EP1076484A4 (de) * | 1998-05-07 | 2001-08-29 | William Douglas Mckee | Ventilanordnung |
US6171590B1 (en) * | 1998-09-30 | 2001-01-09 | Corixa Corporation | Chemokine receptor peptide for inducing an immune response |
EP1127126B1 (de) * | 1998-11-06 | 2006-10-18 | Bayer HealthCare AG | G-protein-gekoppelter rezeptoren, die holomog zu ebv-induzierter gpcr (ebi-2) sind, verfahren zur identifizierung von ihren entsprechenden liganden |
US6329159B1 (en) * | 1999-03-11 | 2001-12-11 | Millennium Pharmaceuticals, Inc. | Anti-GPR-9-6 antibodies and methods of identifying agents which modulate GPR-9-6 function |
US6358697B2 (en) | 1999-04-21 | 2002-03-19 | Children's Hospital Medical Center | Intracellular pharmaceutical targeting |
AU6517400A (en) | 1999-08-03 | 2001-02-19 | Millennium Pharmaceuticals, Inc. | 15571, a novel gpcr-like molecule of the secretin-like family and uses thereof |
WO2001038352A2 (en) * | 1999-11-24 | 2001-05-31 | Schering Corporation | Methods of inhibiting metastasis |
US6949243B1 (en) | 1999-11-24 | 2005-09-27 | Schering Corporation | Methods of inhibiting metastasis |
AU2001249546A1 (en) * | 2000-03-27 | 2001-10-08 | Corixa Corporation | Methods for treating disease with antibodies to cxcr3 |
EP1283057B2 (de) | 2000-04-28 | 2012-05-30 | Chugai Seiyaku Kabushiki Kaisha | Zellproliferation-inhibitoren |
US7052676B2 (en) | 2000-09-26 | 2006-05-30 | The Regents Of The University Of Michigan | Methods for inhibition of HIV replication using a small molecule inhibitor |
US7175988B2 (en) | 2001-02-09 | 2007-02-13 | Human Genome Sciences, Inc. | Human G-protein Chemokine Receptor (CCR5) HDGNR10 |
WO2003006045A2 (en) * | 2001-07-12 | 2003-01-23 | The Regents Of The University Of California | Cxcl10 treatment of secondary tissue degeneration |
US7442512B2 (en) | 2001-11-30 | 2008-10-28 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
US7253007B2 (en) | 2001-11-30 | 2007-08-07 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
US7413866B2 (en) | 2001-11-30 | 2008-08-19 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
US7871619B2 (en) | 2001-11-30 | 2011-01-18 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
US7393934B2 (en) | 2001-12-21 | 2008-07-01 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor (CCR5) HDGNR10 |
EP1491209A4 (de) * | 2002-02-28 | 2006-05-17 | Kyowa Hakko Kogyo Kk | Mittel für die diagnose und behandlung der interstitiellen pneumonie |
US20050119174A1 (en) * | 2002-04-03 | 2005-06-02 | Sumitomo Pharmaceuticals Co. Ltd. | Novel blood sugar controller and method of screening the same |
EP2402310A1 (de) | 2002-05-24 | 2012-01-04 | Millennium Pharmaceuticals, Inc. | CCR9-Hemmer und Verwendungsverfahren dafür |
US7741519B2 (en) | 2007-04-23 | 2010-06-22 | Chemocentryx, Inc. | Bis-aryl sulfonamides |
US7420055B2 (en) | 2002-11-18 | 2008-09-02 | Chemocentryx, Inc. | Aryl sulfonamides |
JP4611746B2 (ja) | 2002-11-18 | 2011-01-12 | ケモセントリックス, インコーポレイテッド | アリールスルホンアミド |
US7227035B2 (en) | 2002-11-18 | 2007-06-05 | Chemocentryx | Bis-aryl sulfonamides |
CA2511242C (en) | 2002-12-20 | 2010-01-12 | Anita Melikian | Inhibitors of human tumor-expressed ccxckr2 |
US7834155B2 (en) | 2003-07-21 | 2010-11-16 | Immunogen Inc. | CA6 antigen-specific cytotoxic conjugate and methods of using the same |
WO2005030793A2 (en) | 2003-09-24 | 2005-04-07 | Millennium Pharmaceuticals, Inc. | Antibodies which bind human cxcr3 |
EP1723970A4 (de) * | 2004-03-09 | 2009-08-12 | Univ Kyoto | Medizinische zusammensetzung mit cxcr3-hemmer |
JP2008507255A (ja) | 2004-03-12 | 2008-03-13 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | ヒトgタンパク質ケモカインレセプター(ccr5)hdgnr10 |
US7622583B2 (en) | 2005-01-14 | 2009-11-24 | Chemocentryx, Inc. | Heteroaryl sulfonamides and CCR2 |
MX2007013108A (es) | 2005-04-21 | 2008-04-07 | Chemocentryx Inc | Reactivos que enlazan ccx-ckr2. |
CA3009680C (en) | 2006-03-16 | 2023-08-15 | Symthera Canada Ltd. | Combination of cytokine and cytokine receptor for altering immune system functioning |
US8519135B2 (en) | 2006-07-14 | 2013-08-27 | Chemocentryx, Inc. | Heteroaryl sulfonamides and CCR2/CCR9 |
WO2008094942A2 (en) * | 2007-02-01 | 2008-08-07 | Teva Biopharmaceuticals Usa, Inc. | Humanized antibodies against cxcr3 |
US7776877B2 (en) | 2007-06-22 | 2010-08-17 | Chemocentryx, Inc. | N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides |
PL2175859T3 (pl) | 2007-07-12 | 2012-09-28 | Chemocentryx Inc | Skondensowane heteroarylopirydylo- i fenylo-benzenosulfonamidy jako modulatory CCR2 do leczenia zapalenia |
SI2804878T1 (sl) * | 2012-01-20 | 2018-12-31 | Genzyme Corporation | Protitelesa proti-CXCR3 |
EP2866830A4 (de) * | 2012-06-27 | 2015-12-09 | Jyant Technologies | Anti-cxcl9-, anti-cxcl10-, anti-cxcl11-, anti-cxcl13-, anti-cxcr3- und anti-cxcr5-wirkstoffe zur hemmung von entzündungen |
WO2014008385A1 (en) | 2012-07-05 | 2014-01-09 | Cornell University | Compositions and methods useful for making orthotopic tumors with controllable metastasis |
WO2014186842A1 (en) * | 2013-05-22 | 2014-11-27 | Monash University | Antibodies and uses thereof |
CA3044621A1 (en) | 2016-11-23 | 2018-05-31 | Chemocentryx, Inc. | Method of treating focal segmental glomerulosclerosis |
EP3551034A1 (de) | 2016-12-07 | 2019-10-16 | Progenity, Inc. | Verfahren, vorrichtungen und systeme zur detektion des magen-darm-trakts |
EP3554541B1 (de) | 2016-12-14 | 2023-06-07 | Biora Therapeutics, Inc. | Behandlung einer erkrankung des gastrointestinaltraktes mit einem chemokin/chemokin-rezeptor-inhibitor |
SG11202002975YA (en) | 2017-10-11 | 2020-04-29 | Chemocentryx Inc | Treatment of focal segmental glomerulosclerosis with ccr2 antagonists |
WO2020106757A1 (en) | 2018-11-19 | 2020-05-28 | Progenity, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
EP3870261B1 (de) | 2019-12-13 | 2024-01-31 | Biora Therapeutics, Inc. | Einnehmbare vorrichtung zur abgabe eines therapeutischen mittels an den magen-darm-trakt |
US20240066061A1 (en) * | 2021-01-12 | 2024-02-29 | Charité-Universitätsmedizin Berlin | A cxcr3+ cell or cell preparation for use in cancer treatment |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG59954A1 (en) * | 1989-08-11 | 1999-02-22 | Amrad Corp Ltd | Improvements in granulocyte-macrophage colony- stimulating factor receptor and derivatives thereof |
EP0669979B1 (de) * | 1992-11-10 | 2005-10-12 | Genentech, Inc. | C-c ckr-1, ein c-c chemokin rezeptor |
US6806061B1 (en) * | 1995-01-19 | 2004-10-19 | Children's Medical Center Corporation | G protein-coupled receptor gene and methods of use therefor |
-
1997
- 1997-09-10 WO PCT/US1997/015915 patent/WO1998011218A1/en active IP Right Grant
- 1997-09-10 AU AU42608/97A patent/AU734090B2/en not_active Ceased
- 1997-09-10 EP EP97940941A patent/EP0925358B1/de not_active Expired - Lifetime
- 1997-09-10 JP JP51377198A patent/JP4502408B2/ja not_active Expired - Fee Related
- 1997-09-10 ES ES97940941T patent/ES2288305T3/es not_active Expired - Lifetime
- 1997-09-10 AT AT97940941T patent/ATE360689T1/de not_active IP Right Cessation
- 1997-09-10 CA CA2265915A patent/CA2265915C/en not_active Expired - Fee Related
- 1997-09-10 DE DE69737656T patent/DE69737656T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2002513388A (ja) | 2002-05-08 |
AU734090B2 (en) | 2001-06-07 |
EP0925358A1 (de) | 1999-06-30 |
AU4260897A (en) | 1998-04-02 |
CA2265915A1 (en) | 1998-03-19 |
ES2288305T3 (es) | 2008-01-01 |
DE69737656D1 (de) | 2007-06-06 |
DE69737656T2 (de) | 2008-01-03 |
CA2265915C (en) | 2012-11-20 |
WO1998011218A1 (en) | 1998-03-19 |
JP4502408B2 (ja) | 2010-07-14 |
EP0925358B1 (de) | 2007-04-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |