CA2264776C - Stable protein and nucleic acid formulations using non-aqueous, anhydrous, aprotic, hydrophobic, non-polar vehicles with low reactivity - Google Patents
Stable protein and nucleic acid formulations using non-aqueous, anhydrous, aprotic, hydrophobic, non-polar vehicles with low reactivity Download PDFInfo
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- CA2264776C CA2264776C CA002264776A CA2264776A CA2264776C CA 2264776 C CA2264776 C CA 2264776C CA 002264776 A CA002264776 A CA 002264776A CA 2264776 A CA2264776 A CA 2264776A CA 2264776 C CA2264776 C CA 2264776C
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurosurgery (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2816796P | 1996-10-16 | 1996-10-16 | |
| US60/028,167 | 1996-10-16 | ||
| US5292097P | 1997-07-15 | 1997-07-15 | |
| US60/052,920 | 1997-07-15 | ||
| PCT/US1997/018575 WO1998016250A1 (en) | 1996-10-16 | 1997-10-15 | Stable protein and nucleic acid formulations using non-aqueous, anhydrous, aprotic, hydrophobic, non-polar vehicles with low reactivity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2264776A1 CA2264776A1 (en) | 1998-04-23 |
| CA2264776C true CA2264776C (en) | 2008-11-25 |
Family
ID=26703379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002264776A Expired - Fee Related CA2264776C (en) | 1996-10-16 | 1997-10-15 | Stable protein and nucleic acid formulations using non-aqueous, anhydrous, aprotic, hydrophobic, non-polar vehicles with low reactivity |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US6264990B1 (OSRAM) |
| EP (1) | EP0939655B1 (OSRAM) |
| JP (1) | JP2002513390A (OSRAM) |
| AR (1) | AR008673A1 (OSRAM) |
| AT (1) | ATE218886T1 (OSRAM) |
| AU (1) | AU4821197A (OSRAM) |
| CA (1) | CA2264776C (OSRAM) |
| DE (1) | DE69713378T2 (OSRAM) |
| IN (1) | IN184589B (OSRAM) |
| WO (1) | WO1998016250A1 (OSRAM) |
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| US7153472B1 (en) | 2000-11-22 | 2006-12-26 | Quadrant Drug Delivery Limited | Preservation and formulation of bioactive materials for storage and delivery in hydrophobic carriers |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2342073A1 (fr) * | 1976-02-27 | 1977-09-23 | Merieux Inst | Nouveau vaccin antivariolique sous forme de pate et son dispositif d'application |
| EP0177342A3 (en) | 1984-10-04 | 1987-12-02 | Genentech, Inc. | Oral formulation of therapeutic proteins |
| IT8922398A0 (it) * | 1989-11-16 | 1989-11-16 | Phidea Spa | Composizioni farmaceutiche ad elevato assorbimento e stabilita', comprendente una calcitonina come sostanza attiva. |
| US5518731A (en) * | 1990-09-27 | 1996-05-21 | Allergan, Inc. | Nonaqueous fluorinated drug delivery vehicle suspensions |
| WO1993025673A1 (en) | 1992-06-04 | 1993-12-23 | The Regents Of The University Of California | In vivo gene therapy with intron-free sequence of interest |
| JP3756512B2 (ja) | 1992-09-21 | 2006-03-15 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 徐放性タンパク質製剤 |
| US5480914A (en) | 1994-05-06 | 1996-01-02 | Allergan, Inc. | Nonaqueous thixotropic drug delivery suspensions and methods of their use |
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| US5811406A (en) | 1995-06-07 | 1998-09-22 | Regents Of The University Of California | Dry powder formulations of polynucleotide complexes |
| IN184589B (OSRAM) * | 1996-10-16 | 2000-09-09 | Alza Corp |
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1997
- 1997-09-23 IN IN1756CA1997 patent/IN184589B/en unknown
- 1997-10-15 AT AT97910959T patent/ATE218886T1/de not_active IP Right Cessation
- 1997-10-15 AR ARP970104744A patent/AR008673A1/es unknown
- 1997-10-15 JP JP51854898A patent/JP2002513390A/ja not_active Ceased
- 1997-10-15 WO PCT/US1997/018575 patent/WO1998016250A1/en not_active Ceased
- 1997-10-15 US US09/269,685 patent/US6264990B1/en not_active Expired - Lifetime
- 1997-10-15 DE DE69713378T patent/DE69713378T2/de not_active Expired - Fee Related
- 1997-10-15 AU AU48211/97A patent/AU4821197A/en not_active Abandoned
- 1997-10-15 EP EP97910959A patent/EP0939655B1/en not_active Expired - Lifetime
- 1997-10-15 CA CA002264776A patent/CA2264776C/en not_active Expired - Fee Related
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2001
- 2001-05-04 US US09/849,402 patent/US6730328B2/en not_active Expired - Lifetime
-
2004
- 2004-01-22 US US10/763,149 patent/US20040151779A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0939655B1 (en) | 2002-06-12 |
| DE69713378T2 (de) | 2003-01-30 |
| US6730328B2 (en) | 2004-05-04 |
| WO1998016250A1 (en) | 1998-04-23 |
| JP2002513390A (ja) | 2002-05-08 |
| DE69713378D1 (de) | 2002-07-18 |
| EP0939655A1 (en) | 1999-09-08 |
| IN184589B (OSRAM) | 2000-09-09 |
| US6264990B1 (en) | 2001-07-24 |
| US20010038859A1 (en) | 2001-11-08 |
| AR008673A1 (es) | 2000-02-09 |
| CA2264776A1 (en) | 1998-04-23 |
| US20040151779A1 (en) | 2004-08-05 |
| ATE218886T1 (de) | 2002-06-15 |
| AU4821197A (en) | 1998-05-11 |
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