CA2262562A1 - Medicament carrier with agglomerated large medicament particles and related method of manufacture thereof - Google Patents

Medicament carrier with agglomerated large medicament particles and related method of manufacture thereof Download PDF

Info

Publication number
CA2262562A1
CA2262562A1 CA002262562A CA2262562A CA2262562A1 CA 2262562 A1 CA2262562 A1 CA 2262562A1 CA 002262562 A CA002262562 A CA 002262562A CA 2262562 A CA2262562 A CA 2262562A CA 2262562 A1 CA2262562 A1 CA 2262562A1
Authority
CA
Canada
Prior art keywords
screen
medicament
interstices
particles
agglomerated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002262562A
Other languages
English (en)
French (fr)
Inventor
Michiel Van Oort
Mark Joseph Sacchetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2262562A1 publication Critical patent/CA2262562A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/005—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a cylindrical surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
CA002262562A 1996-07-31 1997-07-30 Medicament carrier with agglomerated large medicament particles and related method of manufacture thereof Abandoned CA2262562A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9616047.8 1996-07-31
GBGB9616047.8A GB9616047D0 (en) 1996-07-31 1996-07-31 Medicament carrier with agglomerated large medicament particles and related method of manufacture thereof
PCT/EP1997/004128 WO1998004308A1 (en) 1996-07-31 1997-07-30 Medicament carrier with agglomerated large medicament particles and related method of manufacture thereof

Publications (1)

Publication Number Publication Date
CA2262562A1 true CA2262562A1 (en) 1998-02-05

Family

ID=10797779

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002262562A Abandoned CA2262562A1 (en) 1996-07-31 1997-07-30 Medicament carrier with agglomerated large medicament particles and related method of manufacture thereof

Country Status (20)

Country Link
US (1) US6245339B1 (sh)
EP (1) EP0923396A1 (sh)
JP (1) JP2000515787A (sh)
KR (1) KR20000029733A (sh)
CN (1) CN1231617A (sh)
AP (1) AP9901447A0 (sh)
AU (1) AU4012597A (sh)
BR (1) BR9710613A (sh)
CA (1) CA2262562A1 (sh)
CZ (1) CZ29099A3 (sh)
EA (1) EA199900179A1 (sh)
GB (1) GB9616047D0 (sh)
IL (1) IL128148A0 (sh)
IS (1) IS4952A (sh)
NO (1) NO990434L (sh)
NZ (1) NZ333944A (sh)
PL (1) PL331370A1 (sh)
TR (1) TR199900167T2 (sh)
WO (1) WO1998004308A1 (sh)
YU (1) YU4199A (sh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007115395A1 (en) * 2006-04-07 2007-10-18 The University Of Western Ontario Powder inhaler featuring disc with dosing holes

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6761909B1 (en) 1999-12-21 2004-07-13 Rxkinetix, Inc. Particulate insulin-containing products and method of manufacture
WO2001045731A1 (en) 1999-12-21 2001-06-28 Rxkinetix, Inc. Particulate drug-containing products and method of manufacture
SE516555C2 (sv) * 2000-08-04 2002-01-29 Microdrug Ag Elektropulver
GB0127916D0 (en) 2001-11-21 2002-01-16 Rowett Res Inst Method
GB2385020A (en) * 2002-02-07 2003-08-13 Meridica Ltd Medicament container and method of manufacture thereof
SE525027C2 (sv) * 2002-04-12 2004-11-16 Microdrug Ag Anordning utgörande en pulverlufthyvel
PT1531794T (pt) * 2002-06-28 2017-09-14 Civitas Therapeutics Inc Epinefrina inalável
US20040191176A1 (en) * 2003-03-28 2004-09-30 Kaplan Leonard W Formulations for treatment of pulmonary disorders
JP2006130143A (ja) 2004-11-08 2006-05-25 Hitachi Ltd 吸入式投薬器及び薬剤カートリッジ
DE112006001898B4 (de) * 2005-07-21 2013-05-08 National Institute For Materials Science Vorrichtung zur Inhalation von Arzneimitteln
BRPI0821111A2 (pt) * 2007-12-05 2015-06-16 Novartis Ag Recptáculo para uma formulação farmacêutica aerossoliza´vel
MX2011003244A (es) 2008-09-26 2011-04-28 Oriel Therapeutics Inc Inhaladores con discos de vias aereas con canales de vias aereas discretas y discos y metodos relacionados.
ES2550309T3 (es) * 2008-09-26 2015-11-06 Oriel Therapeutics, Inc. Mecanismos inhaladores con perforadores predispuestos radialmente y métodos relacionados
BRPI0919126B1 (pt) 2008-09-26 2021-07-27 Oriel Therapeutics, Inc Inalador de pó seco
US9050427B2 (en) * 2008-09-30 2015-06-09 Oriel Therapeutics, Inc. Dry powder inhalers with multi-facet surface deagglomeration chambers and related devices and methods
CA2732827C (en) * 2008-10-01 2016-10-11 Oriel Therapeutics, Inc. Dry powder inhalers with rotating piercing mechanisms and related devices and methods
USD635246S1 (en) * 2010-03-26 2011-03-29 Oriel Therapeutics, Inc. Dose disk for dry powder inhalers
PL2654864T3 (pl) 2010-12-22 2021-07-12 Syqe Medical Ltd. System dostarczania leku
US9427376B2 (en) * 2013-10-10 2016-08-30 Chiesi Farmaceutici S.P.A. Process for preparing pharmaceutical formulations for inhalation comprising a high-dosage strength active ingredient
US11298477B2 (en) 2014-06-30 2022-04-12 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
CN113616883B (zh) 2014-06-30 2023-06-06 Syqe医药有限公司 向受试者肺部递送植物材料中的至少一药理活性剂的系统
AU2015283594B2 (en) 2014-06-30 2019-07-25 Syqe Medical Ltd. Flow regulating inhaler device
PL3539599T3 (pl) 2014-06-30 2022-02-21 Syqe Medical Ltd. Wkład z dawką leku dla urządzenia inhalatora
MX2017000057A (es) 2014-06-30 2017-06-30 Syqe Medical Ltd Procedimiento y dispositivo para vaporizacion e inhalacion de sustancias aisladas.
AU2015283590B2 (en) 2014-06-30 2020-04-16 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
CN104101557B (zh) * 2014-08-06 2016-08-31 丁盛 颗粒状物料尺寸大小估算测量装置
US11806331B2 (en) 2016-01-06 2023-11-07 Syqe Medical Ltd. Low dose therapeutic treatment
RU2738991C2 (ru) * 2016-07-21 2020-12-21 Филип Моррис Продактс С.А. Ингалятор сухого порошка
DK3519025T3 (da) 2016-09-30 2023-01-30 De Motu Cordis Pty Ltd Indgivelsesanordning
KR101992171B1 (ko) * 2017-06-27 2019-06-25 한국유나이티드제약 주식회사 건조분말 흡입기
CN114632235B (zh) * 2022-03-04 2023-04-25 华中科技大学 一种干粉吸入器

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE438261B (sv) 1981-07-08 1985-04-15 Draco Ab Anvendning i dosinhalator av ett perforerat membran
US4805811A (en) 1985-03-29 1989-02-21 Aktiebolaget Draco Dosage device
SE448277B (sv) 1985-04-12 1987-02-09 Draco Ab Indikeringsanordning vid en doseringsanordning for lekemedel
CA1272917A (en) 1985-07-30 1990-08-21 Paul Kenneth Rand Devices for administering medicaments to patients
US5192548A (en) 1990-04-30 1993-03-09 Riker Laboratoires, Inc. Device
ATE127353T1 (de) 1990-06-28 1995-09-15 Boehringer Ingelheim Kg Vorrichtung und verfahren zur pulverdosierung.
IT1243344B (it) 1990-07-16 1994-06-10 Promo Pack Sa Inalatore plurimonodose per medicamenti in polvere
GB9100163D0 (en) 1991-01-04 1991-02-20 Blakeway Ian Music making machine for playing selected pre-recorded discs
KR960701672A (ko) 1993-03-03 1996-03-28 윌리엄 피. 알트만 건조 분말 흡입기의 약제 캐리어(dry powder inhalator medicament carrier)
US5503869A (en) * 1994-10-21 1996-04-02 Glaxo Wellcome Inc. Process for forming medicament carrier for dry powder inhalator
US5647347A (en) * 1994-10-21 1997-07-15 Glaxo Wellcome Inc. Medicament carrier for dry powder inhalator
PL178716B1 (pl) 1994-10-21 2000-06-30 Glaxo Wellcome Inc Nośnik leku do inhalatora suchych proszków i sposób wytwarzania nośnika leku do inhalatora suchych proszków
US5654007A (en) 1995-06-07 1997-08-05 Inhale Therapeutic Systems Methods and system for processing dispersible fine powders

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007115395A1 (en) * 2006-04-07 2007-10-18 The University Of Western Ontario Powder inhaler featuring disc with dosing holes
US8037880B2 (en) 2006-04-07 2011-10-18 The University Of Western Ontario Dry powder inhaler

Also Published As

Publication number Publication date
US6245339B1 (en) 2001-06-12
GB9616047D0 (en) 1996-09-11
BR9710613A (pt) 1999-08-17
NZ333944A (en) 2000-09-29
EA199900179A1 (ru) 1999-08-26
AU4012597A (en) 1998-02-20
EP0923396A1 (en) 1999-06-23
NO990434D0 (no) 1999-01-29
PL331370A1 (en) 1999-07-05
KR20000029733A (ko) 2000-05-25
WO1998004308A1 (en) 1998-02-05
JP2000515787A (ja) 2000-11-28
NO990434L (no) 1999-03-29
AP9901447A0 (en) 1999-03-31
IS4952A (is) 1999-01-22
CN1231617A (zh) 1999-10-13
CZ29099A3 (cs) 1999-06-16
TR199900167T2 (xx) 1999-04-21
YU4199A (sh) 2000-12-28
IL128148A0 (en) 1999-11-30

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Legal Events

Date Code Title Description
FZDE Discontinued