CA2262446A1 - Self-aligning peptides derived from elastin and other fibrous proteins - Google Patents

Self-aligning peptides derived from elastin and other fibrous proteins Download PDF

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Publication number
CA2262446A1
CA2262446A1 CA002262446A CA2262446A CA2262446A1 CA 2262446 A1 CA2262446 A1 CA 2262446A1 CA 002262446 A CA002262446 A CA 002262446A CA 2262446 A CA2262446 A CA 2262446A CA 2262446 A1 CA2262446 A1 CA 2262446A1
Authority
CA
Canada
Prior art keywords
polypeptide
amino acid
beta
elastin
sheet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002262446A
Other languages
English (en)
French (fr)
Inventor
Aser Rothstein
Fred W. Keeley
Steven J. Rothstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hospital for Sick Children HSC
Protein Specialties Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2262446A1 publication Critical patent/CA2262446A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/70Biological properties of the composition as a whole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/86Products or compounds obtained by genetic engineering
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/92Detection of biochemical

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Birds (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
CA002262446A 1996-08-07 1997-08-07 Self-aligning peptides derived from elastin and other fibrous proteins Abandoned CA2262446A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US2355296P 1996-08-07 1996-08-07
US60/023,552 1996-08-07
US08/911,364 1997-08-07
US08/911,364 US5969106A (en) 1996-08-07 1997-08-07 Self-aligning peptides modeled on human elastin and other fibrous proteins

Publications (1)

Publication Number Publication Date
CA2262446A1 true CA2262446A1 (en) 1998-02-12

Family

ID=26697313

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002262446A Abandoned CA2262446A1 (en) 1996-08-07 1997-08-07 Self-aligning peptides derived from elastin and other fibrous proteins

Country Status (6)

Country Link
US (1) US5969106A (enExample)
EP (1) EP0922058A2 (enExample)
JP (1) JP2001505539A (enExample)
AU (1) AU728480B2 (enExample)
CA (1) CA2262446A1 (enExample)
WO (1) WO1998005685A2 (enExample)

Families Citing this family (24)

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Publication number Priority date Publication date Assignee Title
US20030198956A1 (en) * 2002-02-21 2003-10-23 Lee Makowski Staged assembly of nanostructures
US6489446B1 (en) 1996-08-07 2002-12-03 Hsc Research And Development Limited Partnership Self-aligning peptides modeled on human elastin and other fibrous proteins
CA2262446A1 (en) * 1996-08-07 1998-02-12 Protein Specialties, Ltd. Self-aligning peptides derived from elastin and other fibrous proteins
US6369626B1 (en) 1997-03-21 2002-04-09 Rambus Inc. Low pass filter for a delay locked loop circuit
US20050204408A1 (en) * 1998-07-17 2005-09-15 Weiss Anthony S. Tropoelastin derivatives
AUPO811797A0 (en) 1997-07-18 1997-08-14 University Of Sydney, The Tropoelastin derivatives
US7193043B1 (en) * 1998-07-17 2007-03-20 Weiss Anthony S Tropoelastin derivatives
AUPP472398A0 (en) 1998-07-17 1998-08-13 University Of Sydney, The Protease susceptibility II
US6903244B1 (en) * 1999-02-26 2005-06-07 University Of Utah Research Foundation Mice which are +/− or −/− for the elastin gene as models for vascular disease
US20010053931A1 (en) * 1999-11-24 2001-12-20 Salvatore J. Abbruzzese Thin-layered, endovascular silk-covered stent device and method of manufacture thereof
US6808707B2 (en) * 2000-02-04 2004-10-26 Matrix Design Wound healing compositions and methods using tropoelastin and lysyl oxidase
GB0108767D0 (en) * 2001-04-07 2001-05-30 Univ Leeds Coatings
US6902932B2 (en) * 2001-11-16 2005-06-07 Tissue Regeneration, Inc. Helically organized silk fibroin fiber bundles for matrices in tissue engineering
WO2003069033A1 (en) * 2002-02-14 2003-08-21 The University Of British Columbia α-HELICAL PROTEIN BASED MATERIALS AND METHODS FOR MAKING SAME
AU2003902483A0 (en) * 2003-05-21 2003-06-05 Commonwealth Scientific And Industrial Research Organisation A bioelastomer ii
AU2003902474A0 (en) * 2003-05-21 2003-06-05 Commonwealth Scientific And Industrial Research Organisation A bioelastomer i
CA2669114C (en) 2006-11-13 2014-12-16 The University Of Sydney Use of tropoelastin for repair or restoration of tissue
CA2686895A1 (en) * 2007-05-10 2008-11-20 Elastin Specialties, Inc. Synthetic peptide materials for joint reconstruction, repair and cushioning
US9308070B2 (en) 2008-12-15 2016-04-12 Allergan, Inc. Pliable silk medical device
WO2010102337A1 (en) 2009-03-10 2010-09-16 The University Of Sydney Injectable biomaterials
CN105530951B (zh) 2013-08-13 2019-10-22 爱力根制药国际有限公司 受损组织的再生
SG11202111349QA (en) * 2019-04-12 2021-11-29 Geltor Inc Recombinant elastin and production thereof
WO2022038155A1 (en) * 2020-08-18 2022-02-24 Universität Basel Hemostatic elastin-like polypeptides
CN112745394B (zh) * 2020-12-09 2022-12-06 肽源(广州)生物科技有限公司 一种重组类人胶原蛋白及其制备方法和应用

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4132746A (en) * 1976-07-09 1979-01-02 University Of Alabama, Birmingham Medical & Education Foundation Synthetic elastomeric insoluble cross-linked polypentapeptide
NL7713618A (nl) * 1976-12-11 1978-06-13 Bayer Ag Werkwijze voor de bereiding van een cosmetisch preparaat.
DE2705670C3 (de) * 1977-02-11 1983-11-17 Fa. Carl Freudenberg, 6940 Weinheim Verfahren zur Herstellung von wasserlöslichen Elastin-Hydrolysaten
US4419288A (en) * 1981-08-27 1983-12-06 Seton Company Elastin hydrolyzate
US4474851A (en) * 1981-10-02 1984-10-02 The University Of Alabama In Birmingham Elastomeric composite material comprising a polypeptide
US4474763A (en) * 1982-07-07 1984-10-02 Lubowe Irwin I Skin preparation
US4960423A (en) * 1982-11-17 1990-10-02 Smith Donald W Method of enhancing the attachment of endothelial cells on a matrix and vascular prosthesis with enhanced anti-thrombogenic characteristics
US4589882A (en) * 1983-09-19 1986-05-20 Urry Dan W Enzymatically crosslinked bioelastomers
US4659740A (en) * 1985-02-14 1987-04-21 Polydex Pharmaceuticals Ltd. Cosmetic preparations comprising novel elastin derivatives
FR2598423B1 (fr) * 1985-03-01 1989-03-17 Inst Nat Sante Rech Med Produit a base d'elastine, procede pour sa preparation et ses applications biologiques, en particulier en tant que biomateriaux et supports artificiels
US5223420A (en) * 1985-03-01 1993-06-29 Institut National De La Sante Et De La Recherche Medicale Elastin-based product, a procedure for its preparation and its biological applications; in particular as biomaterials and artificial supports
US5336256A (en) * 1986-04-17 1994-08-09 Uab Research Foundation Elastomeric polypeptides as vascular prosthetic materials
US4870055A (en) * 1986-04-17 1989-09-26 University Of Alabama At Birmingham Segmented polypeptide bioelastomers to modulate elastic modulus
US4783523A (en) * 1986-08-27 1988-11-08 Urry Dan W Temperature correlated force and structure development of elastin polytetrapeptides and polypentapeptides
US5250516A (en) * 1986-04-17 1993-10-05 Uab Research Foundation Bioelastomeric materials suitable for the protection of burn areas or the protection of wound repair sites from the occurrence of adhesions
GB8618374D0 (en) * 1986-07-28 1986-09-03 Hsc Res Dev Corp Biological vascular prostheses
US4979959A (en) * 1986-10-17 1990-12-25 Bio-Metric Systems, Inc. Biocompatible coating for solid surfaces
US5243038A (en) * 1986-11-04 1993-09-07 Protein Polymer Technologies, Inc. Construction of synthetic DNA and its use in large polypeptide synthesis
JPH01501755A (ja) * 1986-11-04 1989-06-22 シントロ コーポレイション 合成dnaの構成および大ポリペプチドの合成におけるその使用
JP2549118B2 (ja) * 1987-05-30 1996-10-30 三省製薬株式会社 乳化組成物
US5606019A (en) * 1987-10-29 1997-02-25 Protien Polymer Technologies, Inc. Synthetic protein as implantables
KR0176966B1 (ko) * 1988-11-09 1999-04-01 제니스 케이. 맥밀리언 재조합 방법으로 제조한 기능적 합성 단백질 폴리머
FR2649982B1 (fr) * 1989-07-20 1991-09-27 Inst Nat Sante Rech Med Membrane biologique artificielle
EP0600869A1 (en) * 1990-05-03 1994-06-15 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging
WO1992009695A1 (en) * 1990-11-28 1992-06-11 E.I. Du Pont De Nemours And Company Structural proteins from artificial genes
GB2273459A (en) * 1992-12-21 1994-06-22 Anthony Joseph Cesaroni Bonding tubes to articles e.g in making panel heat exchangers.
JP3474190B2 (ja) * 1992-12-22 2003-12-08 ザ ユニバーシテイ オブ シドニイ 合成ポリヌクレオチド
US5527610A (en) * 1994-05-20 1996-06-18 The Uab Research Foundation Elastomeric polypeptide matrices for preventing adhesion of biological materials
CA2262446A1 (en) * 1996-08-07 1998-02-12 Protein Specialties, Ltd. Self-aligning peptides derived from elastin and other fibrous proteins

Also Published As

Publication number Publication date
AU3843897A (en) 1998-02-25
EP0922058A2 (en) 1999-06-16
WO1998005685A3 (en) 1998-04-30
US5969106A (en) 1999-10-19
JP2001505539A (ja) 2001-04-24
AU728480B2 (en) 2001-01-11
WO1998005685A2 (en) 1998-02-12

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20121116