CA2251972A1 - Combination therapy for reducing the risks associated with cardiovascular disease - Google Patents
Combination therapy for reducing the risks associated with cardiovascular disease Download PDFInfo
- Publication number
- CA2251972A1 CA2251972A1 CA002251972A CA2251972A CA2251972A1 CA 2251972 A1 CA2251972 A1 CA 2251972A1 CA 002251972 A CA002251972 A CA 002251972A CA 2251972 A CA2251972 A CA 2251972A CA 2251972 A1 CA2251972 A1 CA 2251972A1
- Authority
- CA
- Canada
- Prior art keywords
- hmg
- inhibitor
- pharmaceutically acceptable
- vitamin
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1568996P | 1996-04-17 | 1996-04-17 | |
US60/015,689 | 1996-04-17 | ||
GB9612082.9 | 1996-06-10 | ||
GBGB9612082.9A GB9612082D0 (en) | 1996-06-10 | 1996-06-10 | Combination therapy for reducing the risks associated with cardiovascular disease |
US2097796P | 1996-06-24 | 1996-06-24 | |
US60/020,977 | 1996-06-24 | ||
GB9616804.2 | 1996-08-09 | ||
GBGB9616804.2A GB9616804D0 (en) | 1996-08-09 | 1996-08-09 | Combination therapy for reducing the risks associated with cardiovascular disease |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2251972A1 true CA2251972A1 (en) | 1997-10-23 |
Family
ID=27451457
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002251972A Abandoned CA2251972A1 (en) | 1996-04-17 | 1997-04-14 | Combination therapy for reducing the risks associated with cardiovascular disease |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0904082A4 (de) |
JP (1) | JP2000508659A (de) |
AU (1) | AU732465B2 (de) |
CA (1) | CA2251972A1 (de) |
WO (1) | WO1997038694A1 (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2265827A1 (en) * | 1996-09-18 | 1998-03-26 | Merck & Co., Inc. | Combination therapy for reducing the risks associated with cardiovascular disease |
JP2001517617A (ja) | 1997-09-24 | 2001-10-09 | ノヴァ モレキュラー インク. | 神経変性疾患の治療を目的としてapoeレベルを増加させる方法 |
EP1037623A1 (de) * | 1997-12-12 | 2000-09-27 | Warner-Lambert Company | Hypolipaemische kombinationen aus statin und lp(a)-inhibitoren |
US6235311B1 (en) * | 1998-03-18 | 2001-05-22 | Bristol-Myers Squibb Company | Pharmaceutical composition containing a combination of a statin and aspirin and method |
GB2336534A (en) | 1998-04-24 | 1999-10-27 | Alec James Coppen | Anti-depressant - Folic Acid Combination |
AR030414A1 (es) * | 2000-04-03 | 2003-08-20 | Astrazeneca Ab | Combinacion farmaceutica que comprende un beta bloqueante y un inhibidor de hmg-coa reductasa , formulacion farmaceutica, equipo transportable de partes , uso de esta combinacion y de esta formulacion para preparar medicamentos |
GB2361185A (en) | 2000-04-10 | 2001-10-17 | Nicholas J Wald | Pharmaceutical formulation for the prevention of cardiovascular disease |
WO2001076632A1 (en) * | 2000-04-10 | 2001-10-18 | Wald Nicholas J | Formulation for the prevention of cardiovascular disease |
SE0002354D0 (sv) * | 2000-06-22 | 2000-06-22 | Astrazeneca Ab | New formulation |
US6916849B2 (en) | 2000-10-23 | 2005-07-12 | Sankyo Company, Limited | Compositions for improving lipid content in the blood |
WO2002034261A1 (fr) * | 2000-10-23 | 2002-05-02 | Sankyo Company, Limited | Compositions hypocholesterolemiantes |
CN1240379C (zh) | 2000-11-07 | 2006-02-08 | 三共株式会社 | 过氧化脂质降低剂组合物 |
JP2004514684A (ja) * | 2000-11-29 | 2004-05-20 | スミスクライン・ビーチャム・コーポレイション | 心臓血管健康状態の改善のためのスタチンおよびカルシウムを含有する組成物 |
WO2002047682A1 (fr) * | 2000-12-14 | 2002-06-20 | Sankyo Company, Limited | Composition ameliorant les lipides sanguins |
US7037934B2 (en) | 2000-12-14 | 2006-05-02 | Sankyo Company, Limited | Blood lipid ameliorant composition |
WO2002047683A1 (fr) * | 2000-12-14 | 2002-06-20 | Sankyo Company, Limited | Composition ameliorant les lipides dans le sang |
TWI284529B (en) * | 2000-12-18 | 2007-08-01 | Sankyo Co | A composition for lowering triglyceride |
CZ309209B6 (cs) * | 2001-01-26 | 2022-05-25 | Schering Corporation | Farmaceutický prostředek |
WO2004006919A1 (ja) * | 2002-07-11 | 2004-01-22 | Sankyo Company, Limited | 血中脂質改善又は血中ホモシステイン低下のための医薬組成物 |
JP4611622B2 (ja) * | 2002-07-11 | 2011-01-12 | 第一三共株式会社 | 血中脂質改善又は血中ホモシステイン低下のための医薬組成物 |
AR040588A1 (es) * | 2002-07-26 | 2005-04-13 | Schering Corp | Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa |
JP4607436B2 (ja) * | 2002-08-02 | 2011-01-05 | 第一三共株式会社 | HMG−CoAリダクターゼ阻害剤を含有する医薬組成物 |
CA2494801A1 (en) * | 2002-08-02 | 2004-02-12 | Sankyo Company Limited | Medicinal composition containing hmg-coa reductase inhibitor |
JP2007515435A (ja) * | 2003-12-23 | 2007-06-14 | メディキュア インターナショナル インコーポレイテッド | HMG−CoA還元酵素阻害剤及びビタミンB6関連化合物を含む組成物を用いる併用療法 |
BRPI0509374A (pt) * | 2004-03-29 | 2007-09-11 | Wyeth Corp | suplementos nutricionais multivitamìnicos e minerais |
EP1841436A4 (de) * | 2005-01-05 | 2008-02-20 | Medicure Int Inc | Verbindungen und verfahren zur regulierung der triglyceridspiegel |
AU2007299726A1 (en) * | 2006-09-22 | 2008-03-27 | Braincells, Inc. | Combination comprising an HMG-COA reductase inhibitor and a second neurogenic agent for treating a nervous system disorder and increasing neurogenesis |
EP2810644A1 (de) * | 2013-06-06 | 2014-12-10 | Ferrer Internacional, S.A. | Orale Formulierung zur Behandlung von Herz-Kreislauf-Erkrankungen |
JP6443935B2 (ja) * | 2013-07-26 | 2018-12-26 | 学校法人 久留米大学 | 動脈硬化の治療または予防のためのアスピリンおよび葉酸の併用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3895107A (en) * | 1970-04-15 | 1975-07-15 | Morrison L M | CSA and CSC in man and mammals to inhibit atherosclerosis and the recurrence of cardiovascular incidents in atherosclerotic mammals |
US5084482A (en) * | 1990-04-10 | 1992-01-28 | The Lithox Corporation | Methods for inhibiting inflammatory ischemic, thrombotic and cholesterolemic disease response with methionine compounds |
DE4326698C2 (de) * | 1993-08-09 | 1997-05-28 | Puetter Medice Chem Pharm | Verwendung einer Kombination aus Folsäure, Vitamin B¶6¶ und Vitamin B¶1¶¶2¶ zur Prophylaxe und Therapie von Arteriosklerose |
US5631401A (en) * | 1994-02-09 | 1997-05-20 | Abbott Laboratories | Inhibitors of protein farnesyltransferase and squalene synthase |
-
1997
- 1997-04-14 EP EP97918595A patent/EP0904082A4/de not_active Ceased
- 1997-04-14 AU AU26665/97A patent/AU732465B2/en not_active Ceased
- 1997-04-14 JP JP9537264A patent/JP2000508659A/ja not_active Ceased
- 1997-04-14 CA CA002251972A patent/CA2251972A1/en not_active Abandoned
- 1997-04-14 WO PCT/US1997/006127 patent/WO1997038694A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0904082A4 (de) | 2001-09-26 |
AU2666597A (en) | 1997-11-07 |
JP2000508659A (ja) | 2000-07-11 |
AU732465B2 (en) | 2001-04-26 |
EP0904082A1 (de) | 1999-03-31 |
WO1997038694A1 (en) | 1997-10-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Dead |