CA2228308A1 - Optical microprobes and methods for spectral analysis of materials - Google Patents

Optical microprobes and methods for spectral analysis of materials Download PDF

Info

Publication number
CA2228308A1
CA2228308A1 CA 2228308 CA2228308A CA2228308A1 CA 2228308 A1 CA2228308 A1 CA 2228308A1 CA 2228308 CA2228308 CA 2228308 CA 2228308 A CA2228308 A CA 2228308A CA 2228308 A1 CA2228308 A1 CA 2228308A1
Authority
CA
Canada
Prior art keywords
optical
volume element
tissue
sample
response
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2228308
Other languages
English (en)
French (fr)
Inventor
Mark Modell
Gregory Debaryshe
A. Ze'ev Hed
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medispectra Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/510,041 external-priority patent/US5713364A/en
Application filed by Individual filed Critical Individual
Publication of CA2228308A1 publication Critical patent/CA2228308A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062Arrangements for scanning
    • A61B5/0068Confocal scanning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/4795Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Endoscopes (AREA)
CA 2228308 1995-08-01 1996-08-01 Optical microprobes and methods for spectral analysis of materials Abandoned CA2228308A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US51004395A 1995-08-01 1995-08-01
US08/510,041 1995-08-01
US08/510,043 1995-08-01
US08/510,041 US5713364A (en) 1995-08-01 1995-08-01 Spectral volume microprobe analysis of materials

Publications (1)

Publication Number Publication Date
CA2228308A1 true CA2228308A1 (en) 1997-02-13

Family

ID=27056762

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2228308 Abandoned CA2228308A1 (en) 1995-08-01 1996-08-01 Optical microprobes and methods for spectral analysis of materials

Country Status (6)

Country Link
EP (1) EP0842412A1 (ja)
JP (2) JP3923080B2 (ja)
AU (1) AU6645796A (ja)
CA (1) CA2228308A1 (ja)
MX (1) MX9800874A (ja)
WO (1) WO1997005473A1 (ja)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6104945A (en) * 1995-08-01 2000-08-15 Medispectra, Inc. Spectral volume microprobe arrays
US6084671A (en) * 1997-05-06 2000-07-04 Holcomb; Matthew J. Surface analysis using Gaussian beam profiles
DE19834279C2 (de) * 1998-07-30 2002-09-26 Europ Lab Molekularbiolog Kompaktes Einzelobjektiv Theta-Mikroskop
FR2784749B1 (fr) * 1998-10-14 2000-12-29 Instruments Sa Appareil de caracterisation optique de materiau en couche mince
EP1251779A1 (en) * 2000-01-27 2002-10-30 National Research Council of Canada Visible-near infrared spectroscopy in burn injury assessment
JP3592182B2 (ja) 2000-02-29 2004-11-24 株式会社睦コーポレーション 撮像装置
US20020010401A1 (en) * 2000-05-18 2002-01-24 Andrew Bushmakin Pre- and post-processing of spectral data for calibration using mutivariate analysis techniques
WO2002004929A2 (en) * 2000-07-10 2002-01-17 University Health Network Method and apparatus for high resolution coherent optical imaging
WO2002101339A2 (en) * 2000-10-12 2002-12-19 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US10595710B2 (en) 2001-10-19 2020-03-24 Visionscope Technologies Llc Portable imaging system employing a miniature endoscope
US6863651B2 (en) * 2001-10-19 2005-03-08 Visionscope, Llc Miniature endoscope with imaging fiber system
US20070167681A1 (en) 2001-10-19 2007-07-19 Gill Thomas J Portable imaging system employing a miniature endoscope
DE10246967A1 (de) * 2002-10-09 2004-04-22 Heinrich, Hermann, Dr.rer.nat. Verfahren und Vorrichtung zur nichtinvasiven Untersuchung von Stoffwechselprozessen
US20060258934A1 (en) * 2003-04-23 2006-11-16 Michael Zenge Magnetic resonance locating method
JP2007501447A (ja) * 2003-05-29 2007-01-25 ミシガン大学リージェンツ ダブルクラッドファイバー走査型顕微鏡
US8026942B2 (en) 2004-10-29 2011-09-27 Johnson & Johnson Consumer Companies, Inc. Skin imaging system with probe
US7558416B2 (en) 2006-10-02 2009-07-07 Johnson & Johnson Consumer Companies, Inc. Apparatus and method for measuring photodamage to skin
JP5435532B2 (ja) * 2007-07-17 2014-03-05 富士フイルム株式会社 画像処理システム
US9282926B2 (en) * 2008-12-18 2016-03-15 Sirona Dental Systems Gmbh Camera for recording surface structures, such as for dental purposes
WO2010133485A1 (de) * 2009-05-16 2010-11-25 Boehringer Ingelheim Microparts Gmbh Miniaturisiertes konfokales spektrometer
DE102010036447A1 (de) * 2010-03-26 2011-09-29 Degudent Gmbh Verfahren zur Ermittlung von Materialcharakteristika
EP2620093A1 (en) * 2010-10-29 2013-07-31 Olympus Corporation Optical measurement device and probe
JP2014021274A (ja) * 2012-07-18 2014-02-03 Hamamatsu Photonics Kk 共焦点光生成レンズユニット、光学装置および顕微鏡
WO2017102521A1 (en) 2015-12-15 2017-06-22 Koninklijke Philips N.V. Methods and apparatus for calibrating a medical monitoring device

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3013467A (en) * 1957-11-07 1961-12-19 Minsky Marvin Microscopy apparatus
US4810875A (en) * 1987-02-02 1989-03-07 Wyatt Technology Corporation Method and apparatus for examining the interior of semi-opaque objects
FR2626383B1 (fr) * 1988-01-27 1991-10-25 Commissariat Energie Atomique Procede de microscopie optique confocale a balayage et en profondeur de champ etendue et dispositifs pour la mise en oeuvre du procede
US4934811A (en) * 1988-04-01 1990-06-19 Syntex (U.S.A.) Inc. Apparatus and method for detection of fluorescence or light scatter
JPH0217429A (ja) * 1988-07-05 1990-01-22 Fujitsu Ltd レーザ方式ガスセンサによる濃度測定方法
DE3843876A1 (de) * 1988-12-24 1990-07-12 Leitz Wild Gmbh Spektralmikroskop mit einem photometer
US5257085A (en) * 1991-04-24 1993-10-26 Kaman Aerospace Corporation Spectrally dispersive imaging lidar system
JPH0534086A (ja) * 1991-07-26 1993-02-09 Mitsubishi Heavy Ind Ltd 伝熱フイン
JP2982472B2 (ja) * 1992-03-11 1999-11-22 日産自動車株式会社 塗装面性状測定装置
CA2131060C (en) * 1993-09-03 2005-03-15 Hiroshi Yamamoto Non-invasive blood analyzer and method using the same

Also Published As

Publication number Publication date
JPH11510254A (ja) 1999-09-07
WO1997005473A1 (en) 1997-02-13
JP2006138860A (ja) 2006-06-01
JP3923080B2 (ja) 2007-05-30
MX9800874A (es) 1998-09-30
AU6645796A (en) 1997-02-26
EP0842412A1 (en) 1998-05-20

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