CA2227806C - Spectrometre muni d'une source d'ions pulsee et dispositif de transmission pour amortir la vitesse des ions, et methode d'utilisation - Google Patents
Spectrometre muni d'une source d'ions pulsee et dispositif de transmission pour amortir la vitesse des ions, et methode d'utilisation Download PDFInfo
- Publication number
- CA2227806C CA2227806C CA002227806A CA2227806A CA2227806C CA 2227806 C CA2227806 C CA 2227806C CA 002227806 A CA002227806 A CA 002227806A CA 2227806 A CA2227806 A CA 2227806A CA 2227806 C CA2227806 C CA 2227806C
- Authority
- CA
- Canada
- Prior art keywords
- ions
- ion
- ion source
- source
- spectrometer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/06—Electron- or ion-optical arrangements
- H01J49/062—Ion guides
- H01J49/063—Multipole ion guides, e.g. quadrupoles, hexapoles
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/10—Ion sources; Ion guns
- H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
- H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
- H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/40—Time-of-flight spectrometers
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002227806A CA2227806C (fr) | 1998-01-23 | 1998-01-23 | Spectrometre muni d'une source d'ions pulsee et dispositif de transmission pour amortir la vitesse des ions, et methode d'utilisation |
AT99900849T ATE273561T2 (de) | 1998-01-23 | 1999-01-25 | Spektrometer mit gepulster ionenquelle, kopplungsvorrichtung zur dämpfung der ionenbewegung, und methode zur verwendung derselben |
PCT/CA1999/000034 WO1999038185A2 (fr) | 1998-01-23 | 1999-01-25 | Spectrometre a source ionique a impulsions et appareil de transmission visant a amortir la mobilite ionique, et procede d'utilisation |
DK99900849.3T DK1050061T4 (en) | 1998-01-23 | 1999-01-25 | Spectrometer equipped with pulsed ion source and transmission device for attenuation of ion movement and method of use thereof |
DE1050061T DE1050061T1 (de) | 1998-01-23 | 1999-01-25 | Spektrometer mit gepulster ionenquelle, kopplungsvorrichting zur dämpfung der ionenbewegung, und methode zur verwendung derselben |
DE69919325.7T DE69919325T3 (de) | 1998-01-23 | 1999-01-25 | Spektrometer mit gepulster Ionenquelle, Kopplungsvorrichtung zur Dämpfung der Ionenbewegung, und Methode zur Verwendung derselben |
EP99900849.3A EP1050061B2 (fr) | 1998-01-23 | 1999-01-25 | Spectromètre à source ionique à impulsions et appareil de transmission visant à amortir la mobilité ionique, et procédé d'utilisation |
AU20428/99A AU745866B2 (en) | 1998-01-23 | 1999-01-25 | Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use |
JP2000528992A JP4331398B2 (ja) | 1998-01-23 | 1999-01-25 | パルスイオン源及びイオン運動を制動するための輸送デバイスを備えた分析計並びにその使用方法 |
US09/989,882 US6680475B2 (en) | 1998-01-23 | 2001-11-21 | Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use |
US10/236,514 USRE39099E1 (en) | 1998-01-23 | 2002-09-06 | Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use |
US10/758,511 US6833543B2 (en) | 1998-01-23 | 2004-01-15 | Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use |
US10/919,859 US7189963B2 (en) | 1998-01-23 | 2004-08-17 | Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002227806A CA2227806C (fr) | 1998-01-23 | 1998-01-23 | Spectrometre muni d'une source d'ions pulsee et dispositif de transmission pour amortir la vitesse des ions, et methode d'utilisation |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2227806A1 CA2227806A1 (fr) | 1999-07-23 |
CA2227806C true CA2227806C (fr) | 2006-07-18 |
Family
ID=4162020
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002227806A Expired - Lifetime CA2227806C (fr) | 1998-01-23 | 1998-01-23 | Spectrometre muni d'une source d'ions pulsee et dispositif de transmission pour amortir la vitesse des ions, et methode d'utilisation |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1050061B2 (fr) |
JP (1) | JP4331398B2 (fr) |
AT (1) | ATE273561T2 (fr) |
AU (1) | AU745866B2 (fr) |
CA (1) | CA2227806C (fr) |
DE (2) | DE1050061T1 (fr) |
DK (1) | DK1050061T4 (fr) |
WO (1) | WO1999038185A2 (fr) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5965884A (en) * | 1998-06-04 | 1999-10-12 | The Regents Of The University Of California | Atmospheric pressure matrix assisted laser desorption |
US6849847B1 (en) | 1998-06-12 | 2005-02-01 | Agilent Technologies, Inc. | Ambient pressure matrix-assisted laser desorption ionization (MALDI) apparatus and method of analysis |
GB9820210D0 (en) | 1998-09-16 | 1998-11-11 | Vg Elemental Limited | Means for removing unwanted ions from an ion transport system and mass spectrometer |
ATE480005T1 (de) | 1999-06-11 | 2010-09-15 | Applied Biosystems Llc | Maldi ionenquelle mit gasimpuls, vorrichtung und verfahren zur ermittlung des molekulargewichtes labilen moleküle |
DE10010204A1 (de) | 2000-03-02 | 2001-09-13 | Bruker Daltonik Gmbh | Konditionierung eines Ionenstrahls für den Einschuss in ein Flugzeitmassenspektrometer |
DE10010902A1 (de) | 2000-03-07 | 2001-09-20 | Bruker Daltonik Gmbh | Tandem-Massenspektrometer aus zwei Quadrupolfiltern |
US6586727B2 (en) * | 2000-06-09 | 2003-07-01 | Micromass Limited | Methods and apparatus for mass spectrometry |
CA2340150C (fr) * | 2000-06-09 | 2005-11-22 | Micromass Limited | Methodes et appareil pour la spectrometrie de masse |
GB2370685B (en) | 2000-11-29 | 2003-01-22 | Micromass Ltd | Mass spectrometers and methods of mass spectrometry |
CA2364158C (fr) | 2000-11-29 | 2003-12-23 | Micromass Limited | Spectrometres de masse, et methodes de spectrometrie de masse |
US20020115056A1 (en) | 2000-12-26 | 2002-08-22 | Goodlett David R. | Rapid and quantitative proteome analysis and related methods |
US6617577B2 (en) | 2001-04-16 | 2003-09-09 | The Rockefeller University | Method and system for mass spectroscopy |
EP1430508A1 (fr) | 2001-09-17 | 2004-06-23 | MDS Inc., doing business as MDS Sciex | Procede et dispositif pour le refroidissement et la concentration d'ions |
AU2002349241A1 (en) | 2001-12-14 | 2003-06-30 | Mds Inc., D.B.A. Mds Sciex | Method of chemical of ionization at reduced pressures |
WO2003081205A2 (fr) | 2002-03-21 | 2003-10-02 | Thermo Finnigan Llc | Appareil d'ionisation et procede pour un systeme de spectrometre de masse |
AU2003230093A1 (en) * | 2002-03-28 | 2003-10-13 | Mds Sciex | Method and system for high-throughput quantitation of small molecules using laser desorption and multiple-reaction-monitoring |
US7388194B2 (en) | 2002-03-28 | 2008-06-17 | Mds Sciex Inc. | Method and system for high-throughput quantitation using laser desorption and multiple-reaction-monitoring |
US7405397B2 (en) * | 2002-03-28 | 2008-07-29 | Mds Sciex Inc. | Laser desorption ion source with ion guide coupling for ion mass spectroscopy |
GB0210930D0 (en) | 2002-05-13 | 2002-06-19 | Thermo Electron Corp | Improved mass spectrometer and mass filters therefor |
GB0305796D0 (en) | 2002-07-24 | 2003-04-16 | Micromass Ltd | Method of mass spectrometry and a mass spectrometer |
US6977371B2 (en) | 2003-06-10 | 2005-12-20 | Micromass Uk Limited | Mass spectrometer |
DE102004025841B4 (de) * | 2004-05-24 | 2015-07-09 | Bruker Daltonik Gmbh | Verfahren und Vorrichtung zur massenspektroskopischen Untersuchung von Analyten |
GB0420408D0 (en) * | 2004-09-14 | 2004-10-20 | Micromass Ltd | Mass spectrometer |
DE102004051785B4 (de) * | 2004-10-25 | 2008-04-24 | Bruker Daltonik Gmbh | Proteinprofile mit Luft-MALDI |
ES2389111T3 (es) | 2005-12-02 | 2012-10-23 | Sirtris Pharmaceuticals, Inc. | Ensayos de espectrometría de masas para la actividad acetiltransferasa/desacetilasa |
US8097425B2 (en) | 2006-03-10 | 2012-01-17 | Tethys Bioscience, Inc. | Multiplex protein fractionation |
DE102007043456B4 (de) | 2007-07-31 | 2012-02-09 | Bruker Daltonik Gmbh | Matrixunterstützte Laserdesorption hoher Ionisierungsausbeute |
CN111801574B (zh) | 2018-02-13 | 2024-02-09 | 生物梅里埃有限公司 | 用于确认仪器中带电粒子产生的方法及相关的仪器 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4535235A (en) † | 1983-05-06 | 1985-08-13 | Finnigan Corporation | Apparatus and method for injection of ions into an ion cyclotron resonance cell |
DE3688215T3 (de) † | 1985-05-24 | 2005-08-25 | Thermo Finnigan Llc, San Jose | Steuerungsverfahren für eine Ionenfalle. |
WO1989006044A1 (fr) † | 1987-12-24 | 1989-06-29 | Unisearch Limited | Spectrometre de masse |
CA1307859C (fr) † | 1988-12-12 | 1992-09-22 | Donald James Douglas | Spectrometre de masse a transmission amelioree d'ions |
DE4202123C2 (de) † | 1992-01-27 | 1995-04-06 | Bruker Franzen Analytik Gmbh | Vorrichtung für die massenspektrometrische Untersuchung schneller organischer Ionen |
US5689111A (en) † | 1995-08-10 | 1997-11-18 | Analytica Of Branford, Inc. | Ion storage time-of-flight mass spectrometer |
DE19511333C1 (de) * | 1995-03-28 | 1996-08-08 | Bruker Franzen Analytik Gmbh | Verfahren und Vorrichtung für orthogonalen Einschuß von Ionen in ein Flugzeit-Massenspektrometer |
DE19629134C1 (de) † | 1996-07-19 | 1997-12-11 | Bruker Franzen Analytik Gmbh | Vorrichtung zur Überführung von Ionen und mit dieser durchgeführtes Meßverfahren |
EP1051731B1 (fr) * | 1997-12-05 | 2002-07-03 | University Of British Columbia | Procede d'analyse d'ions dans un appareil comprenant un spectrometre de masse a temps de vol et un piege a ions lineaire |
-
1998
- 1998-01-23 CA CA002227806A patent/CA2227806C/fr not_active Expired - Lifetime
-
1999
- 1999-01-25 AT AT99900849T patent/ATE273561T2/de active
- 1999-01-25 WO PCT/CA1999/000034 patent/WO1999038185A2/fr active IP Right Grant
- 1999-01-25 DE DE1050061T patent/DE1050061T1/de active Pending
- 1999-01-25 EP EP99900849.3A patent/EP1050061B2/fr not_active Expired - Lifetime
- 1999-01-25 AU AU20428/99A patent/AU745866B2/en not_active Expired
- 1999-01-25 DK DK99900849.3T patent/DK1050061T4/en active
- 1999-01-25 JP JP2000528992A patent/JP4331398B2/ja not_active Expired - Lifetime
- 1999-01-25 DE DE69919325.7T patent/DE69919325T3/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU2042899A (en) | 1999-08-09 |
WO1999038185A2 (fr) | 1999-07-29 |
DE69919325T3 (de) | 2017-03-02 |
DK1050061T3 (da) | 2004-11-22 |
DE69919325D1 (de) | 2004-09-16 |
DE69919325T2 (de) | 2005-02-17 |
EP1050061B1 (fr) | 2004-08-11 |
DE1050061T1 (de) | 2001-06-07 |
DK1050061T4 (en) | 2017-01-23 |
AU745866B2 (en) | 2002-04-11 |
WO1999038185A3 (fr) | 1999-10-21 |
ATE273561T2 (de) | 2004-08-15 |
JP4331398B2 (ja) | 2009-09-16 |
JP2002502084A (ja) | 2002-01-22 |
EP1050061A2 (fr) | 2000-11-08 |
CA2227806A1 (fr) | 1999-07-23 |
EP1050061B2 (fr) | 2016-10-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20180123 |