CA2223041A1 - Immunological combination compositions and methods - Google Patents
Immunological combination compositions and methods Download PDFInfo
- Publication number
- CA2223041A1 CA2223041A1 CA002223041A CA2223041A CA2223041A1 CA 2223041 A1 CA2223041 A1 CA 2223041A1 CA 002223041 A CA002223041 A CA 002223041A CA 2223041 A CA2223041 A CA 2223041A CA 2223041 A1 CA2223041 A1 CA 2223041A1
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- Prior art keywords
- antigen
- lipoprotein
- nucleic acid
- composition
- ospa
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6018—Lipids, e.g. in lipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/828—Bacterial vaccine for canidae or mustelidae, e.g. dogs, foxes, minks
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/476,656 US6251405B1 (en) | 1995-06-07 | 1995-06-07 | Immunological combination compositions and methods |
| US08/476,656 | 1995-06-07 | ||
| US08/588,621 | 1996-01-19 | ||
| US08/588,621 US6379675B1 (en) | 1995-06-07 | 1996-01-19 | Immunological combination compositions and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2223041A1 true CA2223041A1 (en) | 1996-12-19 |
Family
ID=23892726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002223041A Abandoned CA2223041A1 (en) | 1995-06-07 | 1996-06-05 | Immunological combination compositions and methods |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US6251405B1 (https=) |
| EP (1) | EP0831937B1 (https=) |
| JP (1) | JPH11510370A (https=) |
| AT (1) | ATE249844T1 (https=) |
| AU (1) | AU717890B2 (https=) |
| CA (1) | CA2223041A1 (https=) |
| DE (1) | DE69630033T2 (https=) |
| FI (1) | FI118591B (https=) |
| IL (1) | IL118579A (https=) |
| NO (1) | NO975620L (https=) |
| WO (1) | WO1996040290A1 (https=) |
| ZA (1) | ZA964894B (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US7008625B2 (en) | 1993-11-01 | 2006-03-07 | Research Foundation Of The State University Of New York | Recombinant constructs of Borrelia burgdorferi |
| ZA964896B (en) * | 1995-06-07 | 1997-01-08 | Connaught Lab | Expression of lipoproteins |
| CN1255850A (zh) * | 1997-05-14 | 2000-06-07 | 盖伦(化学制品)有限公司 | 局部用组合物 |
| WO1999014333A2 (en) * | 1997-09-18 | 1999-03-25 | Pasteur Merieux Connaught | Improved method of production of pneumococcal surface proteins |
| WO2000000218A1 (fr) * | 1998-06-26 | 2000-01-06 | Aventis Pasteur | Immunisation a ciblage mucosal |
| DE69935606T9 (de) | 1998-10-16 | 2021-03-11 | Glaxosmithkline Biologicals S.A. | Adjuvanzsysteme und impfstoffe |
| AU2487300A (en) | 1998-12-31 | 2000-07-31 | Chiron Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| WO2000039302A2 (en) | 1998-12-31 | 2000-07-06 | Chiron Corporation | Improved expression of hiv polypeptides and production of virus-like particles |
| AT407958B (de) | 1999-02-11 | 2001-07-25 | Immuno Ag | Inaktivierte influenza-virus-vakzine zur nasalen oder oralen applikation |
| DE60014076T2 (de) | 1999-04-19 | 2005-10-13 | Glaxosmithkline Biologicals S.A. | Adjuvans-zusammensetzung, enthaltend saponin und ein immunstimulatorisches oligonukleotid |
| EP1194559B1 (en) | 1999-06-18 | 2006-09-20 | Research Foundation Of State University Of New York | Groups of borrelia burgdorferi that cause lyme disease in humans |
| AU3726001A (en) * | 1999-12-09 | 2001-06-18 | Institut Pasteur | Systemic immune response induced by mucosal administration of l ipid-tailed polypeptides without adjuvant |
| US20030232055A1 (en) * | 2000-07-31 | 2003-12-18 | Ruslan Medzhitov | Innate immune system-directed vaccines |
| CA2418036A1 (en) * | 2000-07-31 | 2002-02-07 | Yale University | Innate immune system-directed vaccines |
| EP1939294A1 (en) | 2000-08-18 | 2008-07-02 | Research Foundation Of State University Of New York | Recombinant constructs of borrelia burgdorferi |
| WO2002016421A2 (en) | 2000-08-18 | 2002-02-28 | Research Foundation Of The State University Of New York | Altered ospa of borrelia burgdorferi |
| US20030175287A1 (en) * | 2001-01-03 | 2003-09-18 | Yale University | Innate immune system-directed vaccines |
| AU2002320314A1 (en) | 2001-07-05 | 2003-01-21 | Chiron, Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| US20030170614A1 (en) | 2001-08-31 | 2003-09-11 | Megede Jan Zur | Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof |
| US7923023B2 (en) * | 2002-02-25 | 2011-04-12 | Astech International LLC | Method and composition for delivery of medicants to animals |
| US20080299140A1 (en) * | 2002-05-24 | 2008-12-04 | The Regents Of The University Of California, | Immunogenic Composition and Peptide Sequences for Prevention and Treatment of an Hsv Condition |
| FR2846004B1 (fr) * | 2002-10-16 | 2006-06-23 | Maco Pharma Sa | Composition pour culture de cellules notamment animales ou de tissus, comprenant du polyethylene glycol |
| WO2005115430A1 (en) * | 2004-05-27 | 2005-12-08 | Gropep Limited | Treatment of inflammatory airway disease |
| US8029777B2 (en) * | 2004-08-13 | 2011-10-04 | Marshall Barry J | Helicobacter system and uses thereof |
| WO2006015445A1 (en) | 2004-08-13 | 2006-02-16 | Marshall Barry J | Bacterial delivery system |
| US20070224205A1 (en) | 2006-03-07 | 2007-09-27 | Powell Thomas J | Compositions that include hemagglutinin, methods of making and methods of use thereof |
| RU2348406C1 (ru) * | 2007-05-02 | 2009-03-10 | Федеральное Государственное Учреждение НАУЧНО-ИССЛЕДОВАТЕЛЬСКИЙ ИНСТИУТ ДЕТСКИХ ИНФЕКЦИЙ | Способ лечения бактериальных гнойных менингитов у детей |
| US8426163B2 (en) * | 2007-12-07 | 2013-04-23 | National Health Research Institutes | Production of lipidated proteins in E. coli |
| US8466259B2 (en) * | 2007-12-07 | 2013-06-18 | National Health Research Institutes | Adjuvants |
| EP2274616A1 (en) | 2008-04-22 | 2011-01-19 | The Research Foundation of State University of New York | Borrelia burgdorferi cell envelope protein array |
| US8287880B2 (en) | 2009-06-02 | 2012-10-16 | National Health Research Institutes | Lipidated vaccine against dengue virus infection |
| US8658176B2 (en) * | 2009-06-22 | 2014-02-25 | National Health Research Institutes | Lipidated tumor-associated antigens and immunotherapeutic compositions |
| CN102695523A (zh) * | 2009-09-10 | 2012-09-26 | 诺华有限公司 | 针对呼吸道疾病的组合疫苗 |
| TW201221642A (en) | 2010-11-15 | 2012-06-01 | Nat Health Research Institutes | Method of producing lipidated polypeptides |
| TWI507413B (zh) | 2010-11-15 | 2015-11-11 | Nat Health Research Institutes | 脂質化多抗原表位疫苗 |
| ES2615230T3 (es) | 2010-12-29 | 2017-06-06 | Oceanspar, Inc | Corral para peces con pértiga central y método para retener un pez en aguas abiertas |
| US9943583B2 (en) * | 2013-12-03 | 2018-04-17 | Universität Zürich | Proline-rich peptides protective against S. pneumoniae |
| HK1244534A1 (zh) | 2014-10-07 | 2018-08-10 | The Research Foundation For The State University Of New York | 重组疏螺旋体蛋白及其使用方法 |
| WO2025015077A1 (en) * | 2023-07-10 | 2025-01-16 | Dynavax Technologies Corporation | Lyme disease vaccines comprising an adjuvant and borrelia outer surface protein a and c antigens |
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| DK590288D0 (da) * | 1988-10-24 | 1988-10-24 | Symbicom Ab | Kemiske forbindelser |
| US4302386A (en) * | 1978-08-25 | 1981-11-24 | The Ohio State University | Antigenic modification of polypeptides |
| EP0014815A3 (de) | 1978-12-20 | 1980-10-29 | Ciba-Geigy Ag | Peptidderivate, Verfahren zu deren Herstellung und Zwischenprodukte sowie pharmazeutische Präparate mit einer dieser Verbindungen |
| US4258029A (en) | 1979-04-23 | 1981-03-24 | Connaught Laboratories Limited | Synthetic adjuvants for stimulation of antigenic responses |
| US4455142A (en) | 1980-07-07 | 1984-06-19 | Alza Corporation | Method of coadministering an antigen and an immunopotentiator |
| US4484923A (en) * | 1982-03-25 | 1984-11-27 | Alza Corporation | Method for administering immunopotentiator |
| DE3521994A1 (de) | 1985-06-20 | 1987-01-02 | Bayer Ag | N-(2-aminoacylamido-2-desoxy-hexosyl)-amide-, -carbamate und -harnstoffe, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
| US4839293A (en) * | 1986-02-24 | 1989-06-13 | The Trustees Of Columbia University In The City Of New York | DNA encoding streptavidin, streptavidin produced therefrom, fused polypeptides which include amino acid sequences present in streptavidin and uses thereof |
| US4721617A (en) | 1986-08-14 | 1988-01-26 | Regents Of The University Of Minnesota | Vaccine against lyme disease |
| EP0270295A3 (en) * | 1986-12-03 | 1989-08-02 | Connaught Laboratories Limited | Conjugate vaccine |
| US4879213A (en) * | 1986-12-05 | 1989-11-07 | Scripps Clinic And Research Foundation | Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse |
| US5098997A (en) * | 1987-12-11 | 1992-03-24 | Praxis Biologics, Inc. | Vaccines for Haemophilus influenzae |
| WO1990003441A1 (en) | 1988-09-20 | 1990-04-05 | Marvin Murray | Accelerated microdilution determination of bacteria susceptibility to antibiotics |
| AU7058691A (en) | 1989-12-22 | 1991-07-24 | Mikrogen Molekularbiologische Entwicklungs-Gmbh | Immunologically active proteines from borrelia burgdorferi, related test kits and vaccine |
| CA2032914A1 (en) * | 1989-12-26 | 1991-06-27 | Peter C.K. Lau | Use of bacterial lipoprotein amino terminus in fusion plasmids for in vivo expression of lipid modified polypeptides |
| DK0571538T5 (da) | 1991-02-15 | 2002-03-04 | Uab Research Foundation | Strukturgen for pneumokokprotein |
| JPH07501687A (ja) * | 1991-08-15 | 1995-02-23 | スミスクライン・ビーチャム・バイオロジカルス（ソシエテ・アノニム） | ボレリア・ブルグドルフェリのサブグループのｏｓｐ ａ 蛋白、それをコードしている遺伝子およびワクチン |
| WO1993007897A1 (en) * | 1991-10-21 | 1993-04-29 | Medimmune, Inc. | Bacterial expression vectors containing dna encoding secretion signals of lipoproteins |
| AU2903892A (en) * | 1991-10-22 | 1993-05-21 | Symbicom Aktiebolag | Improvement in (borrelia burgdorferi) diagnosis and prophylaxis |
| CA2105629A1 (en) * | 1992-09-14 | 1994-03-15 | Robert S. Becker | Potentiation of immunogenic response |
| WO1994014318A1 (en) * | 1992-12-24 | 1994-07-07 | Medimmune, Inc. | Method of protection against streptococcus pneumoniae with transformed mycobacteria |
| FR2708622B1 (fr) * | 1993-08-02 | 1997-04-18 | Raymond Hamers | Vecteur recombinant contenant une séquence d'un gène de lipoprotéine de structure pour l'expression de séquences de nucléotides. |
-
1995
- 1995-06-07 US US08/476,656 patent/US6251405B1/en not_active Expired - Fee Related
-
1996
- 1996-01-19 US US08/588,621 patent/US6379675B1/en not_active Expired - Fee Related
- 1996-06-05 IL IL118579A patent/IL118579A/en not_active IP Right Cessation
- 1996-06-05 JP JP9501336A patent/JPH11510370A/ja not_active Ceased
- 1996-06-05 AT AT96919085T patent/ATE249844T1/de not_active IP Right Cessation
- 1996-06-05 EP EP96919085A patent/EP0831937B1/en not_active Expired - Lifetime
- 1996-06-05 CA CA002223041A patent/CA2223041A1/en not_active Abandoned
- 1996-06-05 DE DE69630033T patent/DE69630033T2/de not_active Expired - Fee Related
- 1996-06-05 WO PCT/US1996/008866 patent/WO1996040290A1/en not_active Ceased
- 1996-06-05 AU AU61519/96A patent/AU717890B2/en not_active Ceased
- 1996-06-07 ZA ZA9604894A patent/ZA964894B/xx unknown
-
1997
- 1997-12-04 NO NO975620A patent/NO975620L/no unknown
- 1997-12-05 FI FI974423A patent/FI118591B/fi active IP Right Grant
-
2002
- 2002-03-12 US US10/096,687 patent/US6984385B2/en not_active Expired - Fee Related
-
2005
- 2005-07-01 US US11/173,364 patent/US7235243B2/en not_active Expired - Fee Related
-
2007
- 2007-05-18 US US11/804,446 patent/US20080089911A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20020131983A1 (en) | 2002-09-19 |
| DE69630033T2 (de) | 2004-04-01 |
| NO975620L (no) | 1998-02-04 |
| ZA964894B (en) | 1997-02-24 |
| FI118591B (fi) | 2008-01-15 |
| IL118579A0 (en) | 1996-10-16 |
| IL118579A (en) | 2007-12-03 |
| JPH11510370A (ja) | 1999-09-14 |
| US20080089911A1 (en) | 2008-04-17 |
| EP0831937A4 (en) | 2001-09-19 |
| US20060110408A1 (en) | 2006-05-25 |
| NO975620D0 (no) | 1997-12-04 |
| FI974423A0 (fi) | 1997-12-05 |
| ATE249844T1 (de) | 2003-10-15 |
| AU6151996A (en) | 1996-12-30 |
| US6379675B1 (en) | 2002-04-30 |
| US7235243B2 (en) | 2007-06-26 |
| EP0831937A1 (en) | 1998-04-01 |
| FI974423L (fi) | 1998-02-04 |
| US6251405B1 (en) | 2001-06-26 |
| US6984385B2 (en) | 2006-01-10 |
| AU717890B2 (en) | 2000-04-06 |
| EP0831937B1 (en) | 2003-09-17 |
| WO1996040290A1 (en) | 1996-12-19 |
| DE69630033D1 (de) | 2003-10-23 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued |