CA2206471A1 - Monoclonal antibody fragments having immunosuppressant activity - Google Patents

Monoclonal antibody fragments having immunosuppressant activity

Info

Publication number
CA2206471A1
CA2206471A1 CA002206471A CA2206471A CA2206471A1 CA 2206471 A1 CA2206471 A1 CA 2206471A1 CA 002206471 A CA002206471 A CA 002206471A CA 2206471 A CA2206471 A CA 2206471A CA 2206471 A1 CA2206471 A1 CA 2206471A1
Authority
CA
Canada
Prior art keywords
fab fragment
mab
fab
cells
hla
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002206471A
Other languages
English (en)
French (fr)
Inventor
Damir Vidovic
Zoltan Nagy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2206471A1 publication Critical patent/CA2206471A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002206471A 1994-12-07 1995-11-25 Monoclonal antibody fragments having immunosuppressant activity Abandoned CA2206471A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35091594A 1994-12-07 1994-12-07
US08/350,915 1994-12-07

Publications (1)

Publication Number Publication Date
CA2206471A1 true CA2206471A1 (en) 1996-06-13

Family

ID=23378740

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002206471A Abandoned CA2206471A1 (en) 1994-12-07 1995-11-25 Monoclonal antibody fragments having immunosuppressant activity

Country Status (19)

Country Link
EP (1) EP0787151A1 (xx)
JP (1) JP2001506122A (xx)
CN (1) CN1168679A (xx)
AR (1) AR002005A1 (xx)
AU (1) AU4256096A (xx)
BR (1) BR9509902A (xx)
CA (1) CA2206471A1 (xx)
CO (1) CO4480041A1 (xx)
CZ (1) CZ172497A3 (xx)
FI (1) FI972430A0 (xx)
HU (1) HUT77342A (xx)
IL (1) IL116228A0 (xx)
MA (1) MA23739A1 (xx)
NO (1) NO972522L (xx)
PE (1) PE52996A1 (xx)
PL (1) PL320610A1 (xx)
TR (1) TR199501542A2 (xx)
WO (1) WO1996017874A1 (xx)
ZA (1) ZA9510195B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0893507A1 (en) * 1997-07-25 1999-01-27 Institut Gustave Roussy Use of MHC class II ligands (CD4 and LAG-3) as adjuvant for vaccination and of LAG-3 in cancer treatment
AU5588099A (en) * 1998-08-28 2000-03-21 Dendreon Corporation Selective apoptosis of neoplastic cells by an hla-dr specific monoclonal antibody
EP1156062A1 (en) * 2000-05-12 2001-11-21 GPC Biotech AG Immunomodulatory human MHC class II antigen-binding peptides/proteins
DE60035337T2 (de) * 2000-05-12 2008-02-28 Gpc Biotech Ag Humane Peptide/Proteine, die das Töten von Zellen, einschliesslich lymphoider Tumorzellen, herbeiführen oder bewirken
US7521047B2 (en) 2000-05-12 2009-04-21 Gpc Biotech Ag Human polypeptides causing or leading to the killing of cells including lymphoid tumor cells
WO2003030831A2 (en) 2001-10-11 2003-04-17 Protein Design Labs, Inc. Treatment of prostate cancer by inhibitors of atp synthase
CN1571797A (zh) 2001-10-15 2005-01-26 麒麟麦酒株式会社 抗hla－dr抗体
WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
EP2552483A4 (en) * 2010-04-01 2013-09-25 Immunomedics Inc USE OF ANTIBODIES TO REDUCE THE NUMBER OF CELLS CONTAINING ANTIGENS AND DENDRITIC CELLS
KR102647825B1 (ko) * 2021-07-22 2024-03-14 서울대학교산학협력단 항-hla-dp 단클론 항체 및 이의 용도

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068790B1 (en) * 1981-06-25 1986-02-26 The Board Of Trustees Of The Leland Stanford Junior University Allele specific immunotherapeutic method and dosage form
DE69028713T3 (de) * 1989-12-27 2004-05-13 Centocor, Inc. Schimäre immunoglobuline für cd4-rezeptoren
DK1266965T3 (da) * 1991-07-25 2006-09-25 Biogen Idec Inc Rekombinante antistoffer til human terapi

Also Published As

Publication number Publication date
MA23739A1 (fr) 1996-07-01
HUT77342A (hu) 1998-03-30
BR9509902A (pt) 1997-10-21
TR199501542A2 (tr) 1996-07-21
EP0787151A1 (en) 1997-08-06
MX9704225A (es) 1997-09-30
WO1996017874A1 (en) 1996-06-13
NO972522D0 (no) 1997-06-03
CO4480041A1 (es) 1997-07-09
JP2001506122A (ja) 2001-05-15
CN1168679A (zh) 1997-12-24
AR002005A1 (es) 1998-01-07
FI972430A (fi) 1997-06-06
NO972522L (no) 1997-08-06
CZ172497A3 (en) 1997-10-15
ZA9510195B (en) 1996-06-07
AU4256096A (en) 1996-06-26
PE52996A1 (es) 1996-12-12
IL116228A0 (en) 1996-03-31
FI972430A0 (fi) 1997-06-06
PL320610A1 (en) 1997-10-13

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Legal Events

Date Code Title Description
FZDE Discontinued