CA2193223A1 - Composes tricycliques, leur production et utilisation - Google Patents

Composes tricycliques, leur production et utilisation

Info

Publication number
CA2193223A1
CA2193223A1 CA 2193223 CA2193223A CA2193223A1 CA 2193223 A1 CA2193223 A1 CA 2193223A1 CA 2193223 CA2193223 CA 2193223 CA 2193223 A CA2193223 A CA 2193223A CA 2193223 A1 CA2193223 A1 CA 2193223A1
Authority
CA
Canada
Prior art keywords
group
compound
mmol
optionally substituted
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2193223
Other languages
English (en)
Inventor
Muneo Takatani
Yumiko Shibouta
Kiminori Tomimatsu
Tetsuji Kawamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2193223A1 publication Critical patent/CA2193223A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

L'invention se rapporte à un composé tricyclique de la formule (I') dans laquelle le noyau A est un noyau hétérocyclique contenant de l'azote, et possédant deux atomes d'azote comme hétéro-atomes, et qui est éventuellement substitué par oxo ou thio; le noyau Q peut être éventuellement substitué; Y est un groupe hdyrocarbure éventuellement substitué, un groupe hdyroxyle éventuellement substitué ou un groupe mercapto éventuellement substitué, à l'exclusion d'un groupe méthyle; R?1¿ est un atome d'hydrogène, un atome d'halogène, un groupe hydrocarbure éventuellement substituté ou un groupe acyle, ou un sel de celui-ci. Ce composé présente d'excellentes activités inhibant PDGF (facteur de croissance plaquettaire), des activités anti-hypertensives, des activités apportant une amélioration aux maladies rénales et des activités favorisant la réduction du taux lipidique.
CA 2193223 1994-07-15 1995-07-12 Composes tricycliques, leur production et utilisation Abandoned CA2193223A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP16380294 1994-07-15
JP6/163802 1994-07-15

Publications (1)

Publication Number Publication Date
CA2193223A1 true CA2193223A1 (fr) 1996-02-01

Family

ID=15780987

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2193223 Abandoned CA2193223A1 (fr) 1994-07-15 1995-07-12 Composes tricycliques, leur production et utilisation

Country Status (5)

Country Link
EP (1) EP0771319A1 (fr)
CN (1) CN1067072C (fr)
AU (1) AU2935895A (fr)
CA (1) CA2193223A1 (fr)
WO (1) WO1996002542A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5958942A (en) * 1994-07-15 1999-09-28 Takeda Chemical Industries, Ltd. Tricyclic nitrogen ring compounds, their production and use
CA2214393A1 (fr) * 1996-09-02 1998-03-02 Takeda Chemical Industries, Ltd. Composes tricycliques, leur production et leur utilisation
WO1998029136A1 (fr) * 1996-12-27 1998-07-09 Takeda Chemical Industries, Ltd. Compose tricyclique stabilise
AU6852798A (en) * 1997-04-18 1998-11-13 Takeda Chemical Industries Ltd. Process for producing tricyclic compounds and their intermediates
JP2004107323A (ja) * 2002-07-26 2004-04-08 Nippon Nohyaku Co Ltd 新規なハロアルキルスルホンアニリド誘導体及び除草剤並びにその使用方法
WO2004011429A1 (fr) * 2002-07-26 2004-02-05 Nihon Nohyaku Co., Ltd. Nouveaux derives d'haloalkylsulfonanilide, herbicides et utilisation de ceux-ci
GB0804755D0 (en) 2008-03-14 2008-04-16 Angeletti P Ist Richerche Bio Therapeutic compounds
CN110483499A (zh) 2009-11-05 2019-11-22 圣母大学 咪唑并[1,2-a]吡啶类化合物及其合成及使用方法
EP3328382A4 (fr) 2015-09-17 2018-12-19 Marvin J. Miller Composés hétérocycliques contenant de la benzylamine et compositions utiles contre une infection mycobactérienne
TW202216714A (zh) * 2020-10-26 2022-05-01 大陸商上海青煜醫藥科技有限公司 含氮稠雜環類化合物及其製備方法和應用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2235925B (en) * 1989-09-12 1992-09-30 Sericol Group Ltd Photocurable compositions
WO1991004027A1 (fr) * 1989-09-15 1991-04-04 Pfizer Inc. Nouveaux derives de n-aryle de n-heteroarylamide et d'uree en tant qu'inhibiteurs d'acyl coenzyme a: cholesterol acyl transferase

Also Published As

Publication number Publication date
EP0771319A1 (fr) 1997-05-07
CN1067072C (zh) 2001-06-13
AU2935895A (en) 1996-02-16
CN1153516A (zh) 1997-07-02
WO1996002542A1 (fr) 1996-02-01

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Legal Events

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