CA2179009A1 - Agents anti-inflammatoires a base de composes de di-tert-butylphenol - Google Patents

Agents anti-inflammatoires a base de composes de di-tert-butylphenol

Info

Publication number
CA2179009A1
CA2179009A1 CA002179009A CA2179009A CA2179009A1 CA 2179009 A1 CA2179009 A1 CA 2179009A1 CA 002179009 A CA002179009 A CA 002179009A CA 2179009 A CA2179009 A CA 2179009A CA 2179009 A1 CA2179009 A1 CA 2179009A1
Authority
CA
Canada
Prior art keywords
integer
compound
hydrogen
subject
tert
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002179009A
Other languages
English (en)
Inventor
Thomas Tod Hudec
Maurice Edward Loomans
Joel Ira Shulman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2179009A1 publication Critical patent/CA2179009A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

L'invention porte sur des compositions comprenant: (a) une quantité inoffensive et efficace d'un composé de formule (i) où n est un entier allant de 1 à 5 environ, m est un entier allant de 0 à 3 environ et -R un hydrogène ou un alcanyle C¿1?-C¿3? à chaîne droite ou ramifiée; et (b) un excipient pharmacocompatible. L'invention porte également sur des méthodes de traitement de maladies caractérisées par les inflammations ou douleurs causées par l'arthrite rhumatoïde ou l'ostéoarthrite, par administration à l'homme et à l'animal qui le nécessitent de doses inoffensives et efficaces dudit composé.
CA002179009A 1993-12-17 1994-12-16 Agents anti-inflammatoires a base de composes de di-tert-butylphenol Abandoned CA2179009A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16934793A 1993-12-17 1993-12-17
US169,347 1993-12-17

Publications (1)

Publication Number Publication Date
CA2179009A1 true CA2179009A1 (fr) 1995-06-22

Family

ID=22615292

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002179009A Abandoned CA2179009A1 (fr) 1993-12-17 1994-12-16 Agents anti-inflammatoires a base de composes de di-tert-butylphenol

Country Status (13)

Country Link
EP (1) EP0734256A1 (fr)
JP (1) JPH09506624A (fr)
CN (1) CN1137752A (fr)
AU (1) AU702254B2 (fr)
BR (1) BR9408334A (fr)
CA (1) CA2179009A1 (fr)
CZ (1) CZ285436B6 (fr)
HU (1) HUT74507A (fr)
NO (1) NO962535L (fr)
NZ (1) NZ277986A (fr)
PL (1) PL315061A1 (fr)
SK (1) SK76996A3 (fr)
WO (1) WO1995016443A1 (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4130666A (en) * 1977-05-16 1978-12-19 Riker Laboratories, Inc. Anti-inflammatory method
US5280045A (en) * 1991-10-16 1994-01-18 The Procter & Gamble Company 4(3,5-bis(1,1-dimethylethyl-4-hydroxyphenyl)-4-oxobutanamide compound useful as an anti-inflammatory agent

Also Published As

Publication number Publication date
JPH09506624A (ja) 1997-06-30
CN1137752A (zh) 1996-12-11
SK76996A3 (en) 1997-05-07
WO1995016443A1 (fr) 1995-06-22
NO962535L (no) 1996-08-15
AU702254B2 (en) 1999-02-18
HU9601656D0 (en) 1996-08-28
NZ277986A (en) 1998-03-25
HUT74507A (en) 1997-01-28
CZ285436B6 (cs) 1999-08-11
AU1372295A (en) 1995-07-03
BR9408334A (pt) 1997-08-19
CZ175596A3 (en) 1996-11-13
NO962535D0 (no) 1996-06-14
EP0734256A1 (fr) 1996-10-02
PL315061A1 (en) 1996-09-30

Similar Documents

Publication Publication Date Title
KR100770695B1 (ko) 말초 카나비노이드 수용체 특이적 아고니스트
US4800211A (en) 5-methylthio-3-hydroxybenzo [b]thiophene-2-carboxamide derivatives as cyclooxygenase and lipoxygenase inhibitors
JPH0784437B2 (ja) 複素環レチノイド
NL8502657A (nl) Naftaleenderivaten met een retinoide werking, werkwijzen voor het bereiden ervan alsmede geneeskundige en cosmetische preparaten, die dergelijke derivaten bevatten.
PT88275B (pt) Processo para a preparacao de composicoes farmaceuticas contendo 5-amino ou amino substituido-1,2,3-triazois uteis como agentes antiproliferativos
JP3179501B2 (ja) 抗炎症薬として有用なイオウ含有ジ−ｔ−ブチルフェノール化合物
US5280045A (en) 4(3,5-bis(1,1-dimethylethyl-4-hydroxyphenyl)-4-oxobutanamide compound useful as an anti-inflammatory agent
JPS62108814A (ja) 過酸化脂質生成抑制剤
US5476876A (en) Di-tert-butylphenol compounds useful as anti-inflammatory agents
AU2007224438B2 (en) Autoimmune conditions and NADPH oxidase defects
CA2179009A1 (fr) Agents anti-inflammatoires a base de composes de di-tert-butylphenol
JPS61275274A (ja) １，３−ジチオ−ル−２−イリデン誘導体及びその用途
US4621091A (en) 3-hydroxybenzo[b]thiophene-2-sulfide derivatives compositions, and method of use therefor
JPH0987174A (ja) 鎮痛性および抗炎症性組成物
WO2004092163A1 (fr) Compose de phenylazole, procede de production et medicament antioxydant
AU1007599A (en) Di-tert-butylphenol compounds useful as anti-inflammatory agents
GB2224028A (en) Substituted 5-hydroxy-2,3-dihydrobenzothiophenes as inhibitors of leukotriene biosynthesis
JPH07138226A (ja) 新規な血行促進のために使用する医薬
AU7255700A (en) Sulfur containing di-tert-butylphenol compounds useful as anti-inflammatory agents

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued