CA2178634A1 - Diphenyl-2-propenoates and homologs thereof useful for treating diseases associated with leukotriene b4 - Google Patents
Diphenyl-2-propenoates and homologs thereof useful for treating diseases associated with leukotriene b4Info
- Publication number
- CA2178634A1 CA2178634A1 CA002178634A CA2178634A CA2178634A1 CA 2178634 A1 CA2178634 A1 CA 2178634A1 CA 002178634 A CA002178634 A CA 002178634A CA 2178634 A CA2178634 A CA 2178634A CA 2178634 A1 CA2178634 A1 CA 2178634A1
- Authority
- CA
- Canada
- Prior art keywords
- methyl
- phenyl
- compound
- aliphatic
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/75—Reactions with formaldehyde
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16460493A | 1993-12-09 | 1993-12-09 | |
US08/164,604 | 1993-12-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2178634A1 true CA2178634A1 (en) | 1995-06-15 |
Family
ID=22595252
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002178634A Abandoned CA2178634A1 (en) | 1993-12-09 | 1994-12-05 | Diphenyl-2-propenoates and homologs thereof useful for treating diseases associated with leukotriene b4 |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0732919A4 (ja) |
JP (1) | JPH09506366A (ja) |
CN (1) | CN1139880A (ja) |
AU (1) | AU1398395A (ja) |
CA (1) | CA2178634A1 (ja) |
NZ (1) | NZ278484A (ja) |
WO (1) | WO1995015752A1 (ja) |
ZA (1) | ZA949786B (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6416733B1 (en) | 1996-10-07 | 2002-07-09 | Bristol-Myers Squibb Pharma Company | Radiopharmaceuticals for imaging infection and inflammation |
WO2009125606A1 (ja) * | 2008-04-11 | 2009-10-15 | 株式会社医薬分子設計研究所 | Pai-1阻害剤 |
US8633245B2 (en) | 2008-04-11 | 2014-01-21 | Institute Of Medicinal Molecular Design, Inc. | PAI-1 inhibitor |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993010780A1 (en) * | 1991-12-06 | 1993-06-10 | Smithkline Beecham Corporation | Heterocyclic-substituted pyridine compounds and uses |
MA22926A1 (fr) * | 1992-06-30 | 1994-04-01 | Smithkline Beecham Corp | Procede pour la preparation de nouveaux composes. |
-
1994
- 1994-12-05 WO PCT/US1994/013966 patent/WO1995015752A1/en not_active Application Discontinuation
- 1994-12-05 NZ NZ278484A patent/NZ278484A/en unknown
- 1994-12-05 CN CN94194736A patent/CN1139880A/zh active Pending
- 1994-12-05 JP JP7516266A patent/JPH09506366A/ja active Pending
- 1994-12-05 EP EP95905321A patent/EP0732919A4/en not_active Withdrawn
- 1994-12-05 CA CA002178634A patent/CA2178634A1/en not_active Abandoned
- 1994-12-05 AU AU13983/95A patent/AU1398395A/en not_active Abandoned
- 1994-12-08 ZA ZA949786A patent/ZA949786B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AU1398395A (en) | 1995-06-27 |
NZ278484A (en) | 1998-02-26 |
CN1139880A (zh) | 1997-01-08 |
WO1995015752A1 (en) | 1995-06-15 |
JPH09506366A (ja) | 1997-06-24 |
EP0732919A4 (en) | 1997-05-02 |
ZA949786B (en) | 1995-10-11 |
EP0732919A1 (en) | 1996-09-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |