CA2174552A1 - Derives de flavine utilises comme agents antiviraux - Google Patents
Derives de flavine utilises comme agents antivirauxInfo
- Publication number
- CA2174552A1 CA2174552A1 CA002174552A CA2174552A CA2174552A1 CA 2174552 A1 CA2174552 A1 CA 2174552A1 CA 002174552 A CA002174552 A CA 002174552A CA 2174552 A CA2174552 A CA 2174552A CA 2174552 A1 CA2174552 A1 CA 2174552A1
- Authority
- CA
- Canada
- Prior art keywords
- flavin
- derivative
- treatment
- infection
- viral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
On administre, à des mammifères, divers dérivés de flavine qui servent d'agents antiviraux. La riboflavine et des dérivés de riboflavine sont donnés comme des exemples spécifiques qui peuvent être préférés.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939321558A GB9321558D0 (en) | 1993-10-19 | 1993-10-19 | Anti-viral agents |
GB9321558.0 | 1993-10-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2174552A1 true CA2174552A1 (fr) | 1995-04-27 |
Family
ID=10743784
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2123825A Pending CA2123825A1 (fr) | 1993-10-19 | 1994-05-18 | Agents antiviraux |
CA002174552A Abandoned CA2174552A1 (fr) | 1993-10-19 | 1994-10-19 | Derives de flavine utilises comme agents antiviraux |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2123825A Pending CA2123825A1 (fr) | 1993-10-19 | 1994-05-18 | Agents antiviraux |
Country Status (26)
Country | Link |
---|---|
EP (1) | EP0739208A1 (fr) |
JP (1) | JPH09505804A (fr) |
CN (1) | CN1140992A (fr) |
AP (1) | AP620A (fr) |
AU (1) | AU7943794A (fr) |
BG (1) | BG100599A (fr) |
BR (1) | BR9407862A (fr) |
CA (2) | CA2123825A1 (fr) |
CO (1) | CO4520283A1 (fr) |
CZ (1) | CZ113796A3 (fr) |
EE (1) | EE9600057A (fr) |
GB (2) | GB9321558D0 (fr) |
HR (1) | HRP940688A2 (fr) |
HU (1) | HUT76322A (fr) |
IL (1) | IL111338A0 (fr) |
JO (1) | JO1866B1 (fr) |
MA (1) | MA23356A1 (fr) |
MD (1) | MD960168A (fr) |
NO (1) | NO961547L (fr) |
OA (1) | OA10579A (fr) |
PE (1) | PE5596A1 (fr) |
PL (1) | PL314008A1 (fr) |
SK (1) | SK50696A3 (fr) |
UY (1) | UY23844A1 (fr) |
WO (1) | WO1995011028A1 (fr) |
ZA (1) | ZA948191B (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07188052A (ja) * | 1993-12-27 | 1995-07-25 | Sanwa Kagaku Kenkyusho Co Ltd | インターフェロン用作用効果増強剤及び該増強剤とインターフェロンとを含有する抗ウイルス活性増強組成物 |
US5756479A (en) * | 1994-12-29 | 1998-05-26 | Research Development Foundation | Flavin adenine dinucleotide analogue inhibitors of monoamine oxidase |
US9044523B2 (en) | 2000-06-15 | 2015-06-02 | Terumo Bct, Inc. | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
EP1531823A4 (fr) * | 2002-05-10 | 2007-07-18 | Univ Ohio State | Flavine n-oxydes: agents anti-cancer et agents d'eradication de pathogenes |
ITTO20020622A1 (it) | 2002-07-16 | 2004-01-16 | Dayco Europe Srl | Gruppo integrato puleggia-smorzatore torsionale |
CN100413866C (zh) * | 2002-08-02 | 2008-08-27 | 中国人民解放军军事医学科学院放射医学研究所 | 核黄素衍生物及其制备方法与应用 |
EP2545788A1 (fr) * | 2011-07-13 | 2013-01-16 | Martin Hulliger | Système diététique à plusieurs composants |
JP2018131410A (ja) * | 2017-02-15 | 2018-08-23 | ヒノキ新薬株式会社 | カスパーゼ−3阻害剤とその用途 |
CA3079952A1 (fr) * | 2017-10-24 | 2019-05-02 | Lunella Biotech, Inc. | Mitoflavoscines : ciblage d'enzymes contenant de la flavine eliminant les cellules souches cancereuses (csc) par inhibition de la respiration mitochondriale |
BR112022000175A2 (pt) * | 2019-07-09 | 2022-02-22 | Dsm Ip Assets Bv | Reduzindo a atividade viral de elafibranor com riboflavina ou dha |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4219545A (en) * | 1979-03-23 | 1980-08-26 | Collins Calvin E | Treatment of infectious keratoconjunctivitis in animals |
US4264601A (en) * | 1979-06-12 | 1981-04-28 | The Board Of Regents Of The University Of Oklahoma | Antihypertensive agents and their use in treatment of hypertension |
US4500524A (en) * | 1982-09-15 | 1985-02-19 | Trustees Of Boston University | Tranquilizing and reducing or preventing seizures |
WO1991002529A2 (fr) * | 1989-08-14 | 1991-03-07 | John Bennett Kizer | Produit et methode pour tuer les cellules anormales chez les vertebres |
JP2727471B2 (ja) * | 1989-09-14 | 1998-03-11 | 三井農林株式会社 | インフルエンザウィルス感染予防剤 |
US5192264A (en) * | 1989-10-06 | 1993-03-09 | The Beth Israel Hospital Association | Methods and apparatus for treating disease states using oxidized lipoproteins |
US5217716A (en) * | 1990-07-18 | 1993-06-08 | The Beth Israel Hospital Association | Method for treating viral infections using oxidized lipoproteins |
FR2674753B1 (fr) * | 1991-04-02 | 1995-03-10 | Jean Berque | Nouvelles indications therapeutiques, en particulier pour le traitement du sida, d'un medicament deja existant et fabrique a partir d'une molecule denuee de contre-indications et d'effets indesirables. |
NZ244270A (en) * | 1991-09-13 | 1995-07-26 | Eisai Co Ltd | Injectable composition comprising riboflavin |
WO1993010784A1 (fr) * | 1991-11-25 | 1993-06-10 | University Of Michigan | Composition et procede therapeutiques de prevention de lesions occasionnees par perfusion |
JP3073309B2 (ja) * | 1992-03-27 | 2000-08-07 | 雪印乳業株式会社 | シアル酸結合5−デアザフラビン系化合物 |
-
1993
- 1993-10-19 GB GB939321558A patent/GB9321558D0/en active Pending
-
1994
- 1994-01-19 JO JO19941866A patent/JO1866B1/en active
- 1994-05-18 CA CA2123825A patent/CA2123825A1/fr active Pending
- 1994-10-18 MA MA23679A patent/MA23356A1/fr unknown
- 1994-10-19 PL PL94314008A patent/PL314008A1/xx unknown
- 1994-10-19 HU HU9601006A patent/HUT76322A/hu unknown
- 1994-10-19 EE EE9600057A patent/EE9600057A/xx unknown
- 1994-10-19 AP APAP/P/1994/000695A patent/AP620A/en active
- 1994-10-19 GB GB9421099A patent/GB2283913A/en not_active Withdrawn
- 1994-10-19 PE PE1994253128A patent/PE5596A1/es not_active Application Discontinuation
- 1994-10-19 WO PCT/GB1994/002292 patent/WO1995011028A1/fr not_active Application Discontinuation
- 1994-10-19 UY UY23844A patent/UY23844A1/es unknown
- 1994-10-19 AU AU79437/94A patent/AU7943794A/en not_active Abandoned
- 1994-10-19 HR HR9321558.0A patent/HRP940688A2/hr not_active Application Discontinuation
- 1994-10-19 EP EP94930272A patent/EP0739208A1/fr not_active Withdrawn
- 1994-10-19 CA CA002174552A patent/CA2174552A1/fr not_active Abandoned
- 1994-10-19 SK SK506-96A patent/SK50696A3/sk unknown
- 1994-10-19 CN CN94194350A patent/CN1140992A/zh active Pending
- 1994-10-19 BR BR9407862A patent/BR9407862A/pt not_active Application Discontinuation
- 1994-10-19 CZ CZ961137A patent/CZ113796A3/cs unknown
- 1994-10-19 CO CO94047671A patent/CO4520283A1/es unknown
- 1994-10-19 JP JP7511518A patent/JPH09505804A/ja active Pending
- 1994-10-19 IL IL11133894A patent/IL111338A0/xx unknown
- 1994-10-19 ZA ZA948191A patent/ZA948191B/xx unknown
-
1996
- 1996-04-18 OA OA60815A patent/OA10579A/en unknown
- 1996-04-18 NO NO961547A patent/NO961547L/no unknown
- 1996-05-17 MD MD96-0168A patent/MD960168A/ro not_active Application Discontinuation
- 1996-05-17 BG BG100599A patent/BG100599A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AP9400695A0 (en) | 1995-01-31 |
BR9407862A (pt) | 1997-05-20 |
NO961547D0 (no) | 1996-04-18 |
CZ113796A3 (en) | 1996-11-13 |
JO1866B1 (en) | 1995-12-27 |
GB2283913A (en) | 1995-05-24 |
PE5596A1 (es) | 1996-04-18 |
EE9600057A (et) | 1996-10-15 |
SK50696A3 (en) | 1997-01-08 |
PL314008A1 (en) | 1996-08-05 |
CN1140992A (zh) | 1997-01-22 |
WO1995011028A1 (fr) | 1995-04-27 |
NO961547L (no) | 1996-06-19 |
MA23356A1 (fr) | 1995-07-01 |
UY23844A1 (es) | 1995-03-28 |
AU7943794A (en) | 1995-05-08 |
CA2123825A1 (fr) | 1995-04-20 |
GB9421099D0 (en) | 1994-12-07 |
OA10579A (en) | 2002-06-19 |
CO4520283A1 (es) | 1997-10-15 |
HUT76322A (en) | 1997-08-28 |
BG100599A (en) | 1997-02-28 |
MD960168A (ro) | 1998-04-30 |
ZA948191B (en) | 1995-06-08 |
HRP940688A2 (en) | 1997-04-30 |
GB9321558D0 (en) | 1993-12-08 |
HU9601006D0 (en) | 1996-06-28 |
JPH09505804A (ja) | 1997-06-10 |
AP620A (en) | 1997-10-14 |
EP0739208A1 (fr) | 1996-10-30 |
IL111338A0 (en) | 1994-12-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Boretti et al. | Intravenous vitamin C for reduction of cytokines storm in acute respiratory distress syndrome | |
DK175582B1 (da) | Anvendelse af en 17-ketosteroid forbindelse til brug ved profylakse og behandling af retroviral infektion | |
CZ336899A3 (cs) | Antimikrobiální prevence a léčba lidského viru imunodeficience a dalších infekčních onemocnění | |
JP5469706B2 (ja) | 新規な葉酸代謝拮抗薬の組み合わせ療法 | |
AU7402998A (en) | Hiv and cancer treatment | |
KR20120101153A (ko) | 점막염 및 체중 감소의 예방 및 치료를 위한 조성물 및 방법 | |
Balzarini et al. | Anti‐retrovirus activity of 9‐(2‐phosphonylmethoxyethyl) adenine (PMEA) in vivo increases when it is less frequently administered | |
WO1997004761A1 (fr) | Procede et compositions pour traiter des proliferations anormales de cellules | |
CA2174552A1 (fr) | Derives de flavine utilises comme agents antiviraux | |
US4910224A (en) | Method of modifying the lipid structure and function of cell membranes and pharmaceutical compositions for use therein | |
PL212010B1 (pl) | Zastosowanie diacereiny lub jej farmaceutycznie dopuszczalnej pochodnej | |
WO2001006990A2 (fr) | Utilisation d'etodolac pour traiter le cancer | |
Cartwright et al. | Experimental production of a nutritional macrocytic anemia in swine | |
JPH06506212A (ja) | Hivウイルス系疾病、ヘルペス、色素性網膜炎およびマラリアの治療向けリボフラビンの利用 | |
NL194430C (nl) | Niet-injecteerbaar farmaceutisch preparaat met anti-kankerwerking. | |
US5519028A (en) | Antiviral preparations | |
EP0183352A2 (fr) | Utilisation de suramine pour clinothérapie des infections par quelques-uns des membres de la famille des virus humains leucémiques de cellules-T (HTLV) y compris le virus lymphadénopathique (LAV) | |
Balzarini et al. | Potentiating effect of ribavirin on the anti-retrovirus activity of 3′-azido-2, 6-diaminopurine-2′, 3′-dideoxyriboside in vitro and in vivo | |
EP0476391B1 (fr) | Composition anti-SIDA contenant cépharanthine comme agent thérapeutique | |
GB2319474A (en) | Anti-viral agents | |
Perno et al. | Red blood cells mediated delivery of 9-(2-phosphonylmethoxyethyl) adenine to primary macrophages: efficiency, metabolism and activity against human immunodeficiency virus or herpes simplex virus | |
RU2531945C2 (ru) | Средство против передачи вич/спид половым путем | |
KR20150011386A (ko) | 게르마늄의 착체 화합물, 이를 제조하는 방법, 및 약물 | |
JP2000505433A (ja) | レトロウイルス感染の処置のための3―アミノ―4―ヒドロキシ安息香酸の使用 | |
JP2990015B2 (ja) | 抗hiv剤 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |