CA2167938A1 - Production de proteines de porines gonococciques et de vaccins chez e. coli et salmonella - Google Patents
Production de proteines de porines gonococciques et de vaccins chez e. coli et salmonellaInfo
- Publication number
- CA2167938A1 CA2167938A1 CA002167938A CA2167938A CA2167938A1 CA 2167938 A1 CA2167938 A1 CA 2167938A1 CA 002167938 A CA002167938 A CA 002167938A CA 2167938 A CA2167938 A CA 2167938A CA 2167938 A1 CA2167938 A1 CA 2167938A1
- Authority
- CA
- Canada
- Prior art keywords
- por
- salmonella
- cell
- protein
- plasmid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 230000001052 transient effect Effects 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- ORHBXUUXSCNDEV-UHFFFAOYSA-N umbelliferone Chemical compound C1=CC(=O)OC2=CC(O)=CC=C21 ORHBXUUXSCNDEV-UHFFFAOYSA-N 0.000 description 1
- HFTAFOQKODTIJY-UHFFFAOYSA-N umbelliferone Natural products Cc1cc2C=CC(=O)Oc2cc1OCC=CC(C)(C)O HFTAFOQKODTIJY-UHFFFAOYSA-N 0.000 description 1
- 239000012646 vaccine adjuvant Substances 0.000 description 1
- 229940124931 vaccine adjuvant Drugs 0.000 description 1
- 229940125575 vaccine candidate Drugs 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 108700026220 vif Genes Proteins 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000012130 whole-cell lysate Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Abstract
Cette invention concerne une cellule de Salmonella ou de E. Coli de recombinaison qui exprime une protéine de porine gonococcique ou un fragment de cette dernière; une composition de vaccin comprenant la cellule de Salmonella de recombinaison et un support pharmaceutiquement acceptable, ainsi que des procédés de prévention et de traitement de la blennorragie gonococcique.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10058893A | 1993-07-30 | 1993-07-30 | |
| US08/100,588 | 1993-07-30 | ||
| US18795994A | 1994-01-28 | 1994-01-28 | |
| US08/187,959 | 1994-01-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2167938A1 true CA2167938A1 (fr) | 1995-02-09 |
Family
ID=26797339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002167938A Abandoned CA2167938A1 (fr) | 1993-07-30 | 1994-07-29 | Production de proteines de porines gonococciques et de vaccins chez e. coli et salmonella |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0717774A1 (fr) |
| JP (1) | JPH11501203A (fr) |
| AU (1) | AU7408494A (fr) |
| CA (1) | CA2167938A1 (fr) |
| WO (1) | WO1995004133A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1800385B (zh) * | 2000-02-28 | 2010-06-02 | 启龙有限公司 | 奈瑟球菌蛋白质的异源表达 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1340506C (fr) * | 1987-11-24 | 1999-04-20 | Nicholas H. Carbonetti | Production de proteines i de n. gonorrhoeae, et de vaccins |
| GB8912330D0 (en) * | 1989-05-30 | 1989-07-12 | Wellcome Found | Live vaccines |
| AU1571992A (en) * | 1991-03-14 | 1992-10-21 | University Of North Carolina At Chapel Hill, The | Production of gonorrheal pi proteins and vaccines |
-
1994
- 1994-07-29 AU AU74084/94A patent/AU7408494A/en not_active Abandoned
- 1994-07-29 JP JP7506002A patent/JPH11501203A/ja active Pending
- 1994-07-29 WO PCT/US1994/008586 patent/WO1995004133A1/fr not_active Application Discontinuation
- 1994-07-29 EP EP94924071A patent/EP0717774A1/fr not_active Withdrawn
- 1994-07-29 CA CA002167938A patent/CA2167938A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0717774A1 (fr) | 1996-06-26 |
| JPH11501203A (ja) | 1999-02-02 |
| WO1995004133A1 (fr) | 1995-02-09 |
| AU7408494A (en) | 1995-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |