CA2126826C - Appareil de melange et de verification d'homogeneite en direct - Google Patents

Appareil de melange et de verification d'homogeneite en direct

Info

Publication number
CA2126826C
CA2126826C CA002126826A CA2126826A CA2126826C CA 2126826 C CA2126826 C CA 2126826C CA 002126826 A CA002126826 A CA 002126826A CA 2126826 A CA2126826 A CA 2126826A CA 2126826 C CA2126826 C CA 2126826C
Authority
CA
Canada
Prior art keywords
container
spectroscopic
support
mixture
axle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002126826A
Other languages
English (en)
Other versions
CA2126826A1 (fr
Inventor
Paul K. Aldridge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22190294&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2126826(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of CA2126826A1 publication Critical patent/CA2126826A1/fr
Application granted granted Critical
Publication of CA2126826C publication Critical patent/CA2126826C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00—Mixers with rotating receptacles
    • B01F29/20—Mixers with rotating receptacles with receptacles rotating about an axis at an angle to their longitudinal axis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00—Mixers with rotating receptacles
    • B01F29/40—Parts or components, e.g. receptacles, feeding or discharging means
    • B01F29/401—Receptacles, e.g. provided with liners
    • B01F29/4011—Receptacles, e.g. provided with liners characterised by the shape or cross-section of the receptacle, e.g. of Y-, Z -, S -, or X shape
    • B01F29/40118—V or W shapes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00—Mixers with rotating receptacles
    • B01F29/40—Parts or components, e.g. receptacles, feeding or discharging means
    • B01F29/403—Disposition of the rotor axis
    • B01F29/4036—Disposition of the rotor axis with a plurality of rotating receptacles
    • B01F29/40363—Disposition of the rotor axis with a plurality of rotating receptacles having perpendicular axes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00—Mixers with rotating receptacles
    • B01F29/60—Mixers with rotating receptacles rotating about a horizontal or inclined axis, e.g. drum mixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00—Mixers with rotating receptacles
    • B01F29/60—Mixers with rotating receptacles rotating about a horizontal or inclined axis, e.g. drum mixers
    • B01F29/62—Mixers with rotating receptacles rotating about a horizontal or inclined axis, e.g. drum mixers without bars, i.e. without mixing elements; characterised by the shape or cross section of the receptacle, e.g. of Y-, Z-, S- or X- shape; with cylindrical receptacles rotating about an axis at an angle to their longitudinal axis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/21—Measuring
    • B01F35/213—Measuring of the properties of the mixtures, e.g. temperature, density or colour
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/71705—Feed mechanisms characterised by the means for feeding the components to the mixer using belts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/75—Discharge mechanisms
    • B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
    • B01F35/7547—Discharge mechanisms characterised by the means for discharging the components from the mixer using valves, gates, orifices or openings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Geometry (AREA)
  • Veterinary Medicine (AREA)
  • Accessories For Mixers (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Continuous Casting (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CA002126826A 1993-06-29 1994-06-27 Appareil de melange et de verification d'homogeneite en direct Expired - Fee Related CA2126826C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8523093A 1993-06-29 1993-06-29
US08/085,230 1993-06-29

Publications (2)

Publication Number Publication Date
CA2126826A1 CA2126826A1 (fr) 1994-12-30
CA2126826C true CA2126826C (fr) 1999-02-23

Family

ID=22190294

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002126826A Expired - Fee Related CA2126826C (fr) 1993-06-29 1994-06-27 Appareil de melange et de verification d'homogeneite en direct

Country Status (12)

Country Link
EP (1) EP0631810B1 (fr)
JP (1) JP2650619B2 (fr)
KR (1) KR0162110B1 (fr)
CN (1) CN1062490C (fr)
AT (1) ATE157905T1 (fr)
AU (1) AU660875B2 (fr)
BR (1) BR9402570A (fr)
CA (1) CA2126826C (fr)
DE (1) DE69405483T2 (fr)
DK (1) DK0631810T3 (fr)
ES (1) ES2106449T3 (fr)
GR (1) GR3025143T3 (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITBO940193A1 (it) * 1994-05-06 1995-11-06 Corob Srl Dispositivo di miscelazione di pitture, vernici e prodotti fluidi in generale e procedimento per il suo controllo.
US5504332A (en) * 1994-08-26 1996-04-02 Merck & Co., Inc. Method and system for determining the homogeneity of tablets
EP0706040A1 (fr) * 1994-10-07 1996-04-10 Bp Chemicals S.N.C. Détermination de propriété
EP0706049A1 (fr) * 1994-10-07 1996-04-10 Bp Chemicals S.N.C. Détermination des caractéristiques de craquage
EP0706050A1 (fr) * 1994-10-07 1996-04-10 Bp Chemicals S.N.C. Détermination d'une caractéristique d'un lubrifiant
EP0706041A1 (fr) * 1994-10-07 1996-04-10 Bp Chemicals S.N.C. Détermination de propriété de produits chimiques
EP0801298B1 (fr) * 1996-04-09 2006-06-21 Innovene Europe Limited Procédé de commande de processus
IT232075Y1 (it) * 1994-10-11 1999-08-16 Corob Srl Miscelatore di prodotti generalmente collocati in contenitori e gruppo di sostegno e serraggio per almeno uno di tali contenitori,
DE69631872D1 (de) * 1996-04-09 2004-04-22 Eutech Engineering Solutions L Prozess-Steuerung
SE9802690D0 (sv) * 1998-08-07 1998-08-07 Astra Ab Mixing apparatus
GB0003641D0 (en) * 2000-02-17 2000-04-05 Astrazeneca Uk Ltd Mixing apparatus and method
SE0000522D0 (sv) * 2000-02-17 2000-02-17 Astrazeneca Ab Mixing apparatus
CA2664171A1 (fr) * 2000-02-17 2001-08-23 Ali Mohammed Afnan Appareil et procede de melange
EP1497629A1 (fr) 2002-04-25 2005-01-19 Glaxo Group Limited Systeme de capteur magneto-acoustique et procede associe permettant de detecter des conditions environnementales
DE102007014844B3 (de) * 2007-03-28 2008-06-05 Glatt Systemtechnik Gmbh Verfahren zur Überwachung der optischen Durchlässigkeit eines Beobachtungsfensters und Einrichtung zur Reinigung eines Beobachtungsfensters
JP2009247999A (ja) * 2008-04-07 2009-10-29 Nisshin Engineering Co Ltd 混合装置
EP2431729A1 (fr) * 2010-01-15 2012-03-21 Malvern Instruments Limited Caractérisation spectrométrique de l'hétérogénéité
DE102011113880A1 (de) 2011-09-22 2013-03-28 Haver Engineering Gmbh Pelletiereinrichtung und Verfahren
CN103657488A (zh) * 2013-12-18 2014-03-26 常熟振氟新材料有限公司 新型v型混合机
CN103940785A (zh) * 2014-04-10 2014-07-23 江苏大学 一种基于透射和散射的混药浓度在线测量装置
CN104596934A (zh) * 2014-12-30 2015-05-06 浙江海洋学院 带有混合器的分光光度计
CN106064034A (zh) * 2016-07-04 2016-11-02 苏州北开生化设备有限公司 一种可自控的真空v型混合机及其使用方法
CN106268456A (zh) * 2016-08-26 2017-01-04 天津市金桥焊材集团有限公司 一种药粉混合装置
CN107824098B (zh) * 2017-11-23 2024-01-19 广东嘉俊陶瓷有限公司 基料搅拌机构
CN108267565B (zh) * 2018-01-03 2022-03-11 西南石油大学 一种检测稠油稀油混合均匀程度及混合后发生二次分离的装置及方法
CN108854656A (zh) * 2018-05-03 2018-11-23 柳伟军 一种石油提炼催化剂沸石分子筛生产用原料混合机
CN109012376B (zh) * 2018-08-10 2021-06-29 昆明理工大学 一种高通量高效混粉机
CN109569358A (zh) * 2018-12-19 2019-04-05 长沙凯天工研院环保服务有限公司 在线近红外光谱监测土壤稳定化过程的搅拌装备
CN110411978B (zh) * 2019-07-26 2020-05-22 中国农业大学 一种物料均匀性检测设备及检测方法
CN113203827B (zh) * 2020-03-03 2023-09-29 大唐环境产业集团股份有限公司 一种多路抽样混合搅拌测量NOx的方法及装置
CN112206711B (zh) * 2020-09-10 2022-06-17 佛山科学技术学院 一种试剂混匀状态检测方法、装置及系统
CN112206702A (zh) * 2020-09-27 2021-01-12 重庆航天工业有限公司 一种自动混合装置与系统
CN112588157B (zh) * 2020-11-20 2023-12-12 湖南开磷雁峰塔涂料有限公司 一种防腐涂料用混匀搅拌设备
CN112717838B (zh) * 2020-12-30 2022-07-26 山东鑫生工贸有限公司 一种旋转反应催化装置
CN112871002A (zh) * 2021-01-12 2021-06-01 长飞光纤光缆股份有限公司 一种多组分粉体原料的匀混方法
CN114471275A (zh) * 2021-12-30 2022-05-13 西安近代化学研究所 一种混同滚筒、药料混同检测设备、方法及应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB590441A (en) * 1945-04-18 1947-07-17 Sidney Tyler Improvements relating to blending apparatus of the rotary drum mixer type
US2514126A (en) * 1949-12-08 1950-07-04 Patterson Kelley Co Blending or mixing apparatus
DE1905290A1 (de) * 1969-02-04 1970-10-01 Dynamit Nobel Ag Drehdurchfuehrung an rotierenden Behaeltern
GB1386312A (en) * 1972-10-30 1975-03-05 Inoue Japax Res Manufacture of settable dental compositions
GB1545538A (en) * 1975-11-17 1979-05-10 Gradient Pty Ltd Method and apparatus for simultaneously recording reaction times
JPS54127065A (en) * 1978-03-22 1979-10-02 Kubota Ltd Position control device of mixer
US4361404A (en) * 1981-04-06 1982-11-30 Pettibone Corporation Mixing equipment and agitator therefor for use with granular material and method of producing prepared granular material
DE3337403A1 (de) * 1983-10-14 1985-05-02 Seyd Fertigbeton Berlin, Zweigniederlassung der Readymix Transportbeton GmbH, 4030 Ratingen Verfahren und vorrichtung zum herstellen von gemischen
DE3412620A1 (de) * 1984-04-04 1985-10-17 Basf Ag, 6700 Ludwigshafen Laseroptische anordnung zur messung des dispergiergrades in stroemenden systemen
JPS61230727A (ja) * 1985-04-03 1986-10-15 Nippon Paint Co Ltd 分散装置
SU1402856A1 (ru) * 1985-12-13 1988-06-15 Ивановский государственный университет Устройство дл приготовлени термохромных композиций и измерени их цветотемпературных характеристик
JPH02273535A (ja) * 1989-04-13 1990-11-08 Fujitsu Ltd ガス流量制御装置
GB2252259A (en) * 1990-12-19 1992-08-05 Unilever Plc Controlling process for producing dispersions
JPH0516134A (ja) * 1991-06-06 1993-01-26 Yokohama Rubber Co Ltd:The 密閉式混合機の制御方法及びその装置

Also Published As

Publication number Publication date
JPH0768146A (ja) 1995-03-14
ATE157905T1 (de) 1997-09-15
DK0631810T3 (da) 1997-10-20
DE69405483T2 (de) 1998-01-15
GR3025143T3 (en) 1998-02-27
JP2650619B2 (ja) 1997-09-03
EP0631810A1 (fr) 1995-01-04
EP0631810B1 (fr) 1997-09-10
CA2126826A1 (fr) 1994-12-30
AU6599794A (en) 1995-01-27
CN1100002A (zh) 1995-03-15
ES2106449T3 (es) 1997-11-01
KR950001299A (ko) 1995-01-03
AU660875B2 (en) 1995-07-06
BR9402570A (pt) 1995-04-11
DE69405483D1 (de) 1997-10-16
KR0162110B1 (ko) 1998-11-16
CN1062490C (zh) 2001-02-28

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