CA2101417A1 - Prophylactic and therapeutic treatment of alzheimer's disease - Google Patents

Prophylactic and therapeutic treatment of alzheimer's disease

Info

Publication number
CA2101417A1
CA2101417A1 CA002101417A CA2101417A CA2101417A1 CA 2101417 A1 CA2101417 A1 CA 2101417A1 CA 002101417 A CA002101417 A CA 002101417A CA 2101417 A CA2101417 A CA 2101417A CA 2101417 A1 CA2101417 A1 CA 2101417A1
Authority
CA
Canada
Prior art keywords
calpain
alzheimer
disease
journal
brain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002101417A
Other languages
English (en)
French (fr)
Inventor
Ken-Ichi Saito
Ralph A. Nixon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mclean Hospital Corp
Original Assignee
Mclean Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mclean Hospital Corp filed Critical Mclean Hospital Corp
Publication of CA2101417A1 publication Critical patent/CA2101417A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002101417A 1992-08-14 1993-07-27 Prophylactic and therapeutic treatment of alzheimer's disease Abandoned CA2101417A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93064792A 1992-08-14 1992-08-14
US930,647 1992-08-14

Publications (1)

Publication Number Publication Date
CA2101417A1 true CA2101417A1 (en) 1994-02-15

Family

ID=25459574

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002101417A Abandoned CA2101417A1 (en) 1992-08-14 1993-07-27 Prophylactic and therapeutic treatment of alzheimer's disease

Country Status (4)

Country Link
JP (1) JPH06172211A (ko)
KR (1) KR940003550A (ko)
CA (1) CA2101417A1 (ko)
TW (1) TW268896B (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2201524T3 (es) * 1997-09-04 2004-03-16 Nippon Chemiphar Co., Ltd. Derivados de epoxisuccinamida.

Also Published As

Publication number Publication date
JPH06172211A (ja) 1994-06-21
TW268896B (ko) 1996-01-21
KR940003550A (ko) 1994-03-12

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Legal Events

Date Code Title Description
FZDE Dead