CA2091335A1 - Anticorps pour la prevention et le traitement de l'infection chez les animaux et les humains - Google Patents

Anticorps pour la prevention et le traitement de l'infection chez les animaux et les humains

Info

Publication number
CA2091335A1
CA2091335A1 CA002091335A CA2091335A CA2091335A1 CA 2091335 A1 CA2091335 A1 CA 2091335A1 CA 002091335 A CA002091335 A CA 002091335A CA 2091335 A CA2091335 A CA 2091335A CA 2091335 A1 CA2091335 A1 CA 2091335A1
Authority
CA
Canada
Prior art keywords
antibody
rsv
altered
human
approximately
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002091335A
Other languages
English (en)
Inventor
William J. Harris
Philip R. Tempest
Geraldine Taylor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SCOTGEN Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2091335A1 publication Critical patent/CA2091335A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2/00Peptides of undefined number of amino acids; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1027Paramyxoviridae, e.g. respiratory syncytial virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002091335A 1990-09-11 1991-09-11 Anticorps pour la prevention et le traitement de l'infection chez les animaux et les humains Abandoned CA2091335A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909019812A GB9019812D0 (en) 1990-09-11 1990-09-11 Novel antibodies for treatment and prevention of infection in animals and man
GB9019812.8 1990-09-11

Publications (1)

Publication Number Publication Date
CA2091335A1 true CA2091335A1 (fr) 1992-03-12

Family

ID=10682003

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002091335A Abandoned CA2091335A1 (fr) 1990-09-11 1991-09-11 Anticorps pour la prevention et le traitement de l'infection chez les animaux et les humains

Country Status (12)

Country Link
EP (1) EP0548190A1 (fr)
JP (1) JPH06501152A (fr)
KR (1) KR930702519A (fr)
AU (1) AU654827B2 (fr)
CA (1) CA2091335A1 (fr)
GB (1) GB9019812D0 (fr)
IE (1) IE913177A1 (fr)
MX (1) MX9101046A (fr)
NZ (1) NZ239728A (fr)
PT (1) PT98944B (fr)
WO (1) WO1992004381A1 (fr)
ZA (1) ZA917170B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7118866B2 (en) 1991-04-10 2006-10-10 The Scripps Research Institute Heterodimeric receptor libraries using phagemids

Families Citing this family (75)

* Cited by examiner, † Cited by third party
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US5859205A (en) * 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
US6750325B1 (en) 1989-12-21 2004-06-15 Celltech R&D Limited CD3 specific recombinant antibody
DE69130708T2 (de) * 1990-07-19 1999-05-27 Us Commerce Verbesserte immunotherapeutische methode zur verhinderung oder behandlung viraler krankheiten der atemwege
US5994510A (en) * 1990-12-21 1999-11-30 Celltech Therapeutics Limited Recombinant antibodies specific for TNFα
US6800738B1 (en) 1991-06-14 2004-10-05 Genentech, Inc. Method for making humanized antibodies
JP4124480B2 (ja) 1991-06-14 2008-07-23 ジェネンテック・インコーポレーテッド 免疫グロブリン変異体
WO1994004679A1 (fr) * 1991-06-14 1994-03-03 Genentech, Inc. Procede pour fabriquer des anticorps humanises
US5824307A (en) * 1991-12-23 1998-10-20 Medimmune, Inc. Human-murine chimeric antibodies against respiratory syncytial virus
US5646253A (en) * 1994-03-08 1997-07-08 Memorial Sloan-Kettering Cancer Center Recombinant human anti-LK26 antibodies
GB9207479D0 (en) * 1992-04-06 1992-05-20 Scotgen Ltd Novel antibodies for treatment and prevention of respiratory syncytial virus infection in animals and man
US6685942B1 (en) 1993-12-10 2004-02-03 The Scripps Research Institute Human neutralizing monoclonal antibodies to respiratory syncytial virus
EP0671927B1 (fr) * 1992-09-16 2003-01-15 The Scripps Research Institute Anticorps monoclonaux et humains neutralisants contre le virus respiratoire syncytial
ATE182625T1 (de) 1993-01-12 1999-08-15 Biogen Inc Rekombinante anti-vla4 antikörpermoleküle
NZ269735A (en) * 1993-07-30 1998-01-26 Oravax Inc Monoclonal iga antibody against respiratory syncytial virus (rsv)
US5429746A (en) 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
US6310185B1 (en) * 1994-03-08 2001-10-30 Memorial Sloan Kettering Cancer Center Recombinant human anti-Lewis Y antibodies
WO1995031546A1 (fr) * 1994-04-28 1995-11-23 Scotgen Biopharmaceuticals, Inc. Anticorps humains recombines diriges contre le virus zosterien de la varicelle
AU7240096A (en) * 1995-09-18 1997-04-09 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Neutralizing monoclonal antibodies to respiratory syncytial virus
CA2257357C (fr) 1996-06-07 2010-04-13 Neorx Corporation Anticorps humanises a glycosylation modifiee
ZA98656B (en) 1997-01-27 1998-08-17 Ludwig Inst Cancer Res Lage-1 tumer associated nucleic acids
ATE530180T1 (de) 1997-04-02 2011-11-15 Brigham & Womens Hospital Verfahren zur ermittlung der individualen risikoprofile atherosklerotischen erkrankungen
US6160099A (en) * 1998-11-24 2000-12-12 Jonak; Zdenka Ludmila Anti-human αv β3 and αv β5 antibodies
AU776672B2 (en) 1998-12-30 2004-09-16 Beth Israel Deaconess Medical Center Characterization of a calcium channel family
US7166573B1 (en) 1999-05-28 2007-01-23 Ludwig Institute For Cancer Research Breast, gastric and prostate cancer associated antigens and uses therefor
EP1218538A2 (fr) 1999-06-30 2002-07-03 Ludwig Institute For Cancer Research Antigenes associes au cancer et leurs utilisations
EP1207905B1 (fr) 1999-09-03 2010-09-01 The Brigham And Women's Hospital, Inc. Techniques et compositions destinees au traitement de maladie inflammatoire par utilisation d'agents de modulation cadherine-11
JP2003512057A (ja) 1999-10-19 2003-04-02 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ Mage−a12抗原ペプチド及びその利用
CN1420723A (zh) * 1999-12-23 2003-05-28 Icn药品公司 L-核苷、l-核苷酸及其类似物的组合物和方法
DE10211088A1 (de) 2002-03-13 2003-09-25 Ugur Sahin Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
ES2573471T3 (es) 2002-05-09 2016-06-08 The Brigham And Women's Hospital, Inc. 1L1RL-1 como un marcador de enfermedades cardiovasculares
DE10254601A1 (de) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
NZ603330A (en) 2003-02-11 2015-02-27 Shire Human Genetic Therapies Diagnosis and treatment of multiple sulfatase deficiency and other sulfatase deficiencies
DK2384753T3 (en) 2003-08-29 2016-04-11 Brigham & Womens Hospital Hydantoin derivatives as inhibitors of cell necrosis
DE10341812A1 (de) 2003-09-10 2005-04-07 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
DE10344799A1 (de) 2003-09-26 2005-04-14 Ganymed Pharmaceuticals Ag Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
DE102004023187A1 (de) 2004-05-11 2005-12-01 Ganymed Pharmaceuticals Ag Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
DE102004024617A1 (de) 2004-05-18 2005-12-29 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
WO2006042192A2 (fr) 2004-10-06 2006-04-20 The Brigham And Womens's Hospital, Inc. Pertinence de niveaux obtenus de marqueurs d'inflammation generalisee a la suite d'un traitement
DE102005013846A1 (de) 2005-03-24 2006-10-05 Ganymed Pharmaceuticals Ag Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
EP1762575A1 (fr) 2005-09-12 2007-03-14 Ganymed Pharmaceuticals AG Identification d' antigènes associés aux tumeurs pour diagnose et thérapie
EP1790664A1 (fr) 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Anticorps monoclonaux contre claudin-18 pour le traitement du cancer
EP1795596A1 (fr) 2005-12-08 2007-06-13 Ganymed Pharmaceuticals AG Compositions et méthodes pour le diagnostic et la thérapie des cancers
DE102005059242A1 (de) 2005-12-12 2007-06-14 Johannes Gutenberg-Universität Mainz, Vertreten Durch Den Präsidenten Molekulare Marker für eine Tumordiagnose und -therapie
AU2007239679B2 (en) 2006-04-13 2012-10-11 Chugai Seiyaku Kabushiki Kaisha Taurine transporter gene
EP1911851A1 (fr) 2006-10-12 2008-04-16 Ganymed Pharmaceuticals AG Compositions et méthodes pour la thérapie et le diagnostic du cancer et ses métastases
EP2463303B1 (fr) 2007-02-23 2014-04-30 The United States of America as represented by the Secretary, Department of Health and Human Services Anticorps monoclonaux pour neutraliser la toxine d'anthrax
JP5635260B2 (ja) 2007-03-15 2014-12-03 中外製薬株式会社 ポリペプチドの製造方法
US8697397B2 (en) 2007-08-07 2014-04-15 Chugai Seiyaku Kabushiki Kaisha Method of producing heterogeneous protein
RU2486245C2 (ru) 2007-10-15 2013-06-27 Чугаи Сейяку Кабусики Кайся Способ получения клетки, способной продуцировать гетеропротеины с высоким выходом
EP2060583A1 (fr) 2007-10-23 2009-05-20 Ganymed Pharmaceuticals AG Identification des marqueurs associés aux tumeurs pour diagnostic et thérapie
WO2009054433A1 (fr) * 2007-10-24 2009-04-30 Chugai Seiyaku Kabushiki Kaisha Cellule destinée à être utilisée dans la production de protéine exogène, et procédé de production utilisant une telle cellule
EP2108701A1 (fr) 2008-04-10 2009-10-14 Ganymed Pharmaceuticals AG Procédés comprenant MS4A12 et agents cibles MS4A12 pour thérapie, diagnostic et test
EP2318048B1 (fr) * 2008-07-21 2019-05-29 Immunomedics, Inc. Variants structuraux d'anticorps pour obtenir de meilleures caractéristiques thérapeutiques
EP2221063A1 (fr) 2009-02-20 2010-08-25 Ganymed Pharmaceuticals AG Procédé et compositions pour le diagnostic et le traitement du cancer
CN107028969A (zh) 2009-02-20 2017-08-11 加尼梅德药物公司 用于癌症诊断和治疗的方法和组合物
EP2221375A1 (fr) 2009-02-20 2010-08-25 Ganymed Pharmaceuticals AG Procédé et compositions pour le diagnostic et le traitement du cancer
EP2423309B1 (fr) 2009-04-22 2018-01-03 Chugai Seiyaku Kabushiki Kaisha Procédé de préparation d'une cellule capable d'une forte production de protéine hétérogène
EP2249159A1 (fr) 2009-04-29 2010-11-10 Ganymed Pharmaceuticals AG Identification des marqueurs associés aux tumeurs pour diagnostic et thérapie
ES2649389T3 (es) 2009-11-11 2018-01-11 Ganymed Pharmaceuticals Gmbh Anticuerpos específicos para claudina 6 (CLDN6)
HUE035098T2 (en) 2010-04-16 2018-05-02 Biogen Ma Inc Anti-VLA4 Antibodies
US20130052209A1 (en) * 2010-04-23 2013-02-28 Purdue Research Foundation Protein drug formulations and packages
ES2596431T3 (es) 2010-05-04 2017-01-09 The Brigham And Women's Hospital, Inc. Antagonista de cadherina-11 para el tratamiento de fibrosis
EP2404936A1 (fr) 2010-07-06 2012-01-11 Ganymed Pharmaceuticals AG Thérapie du cancer utilisant des anticorps in vivo dirigés sur la cible CLDN6
RS54627B1 (en) 2011-05-13 2016-08-31 Ganymed Pharmaceuticals Ag CANCER EXPRESSION ANTIBODIES THAT EXPLAIN CLAUDINE 6
WO2013078122A1 (fr) 2011-11-22 2013-05-30 President And Fellows Of Harvard College Diagnostic du diabète par l'intermédiaire de la détection de protéines glycatées dans l'urine
WO2013167153A1 (fr) 2012-05-09 2013-11-14 Ganymed Pharmaceuticals Ag Anticorps utiles dans le diagnostic du cancer
WO2014145022A1 (fr) 2013-03-15 2014-09-18 President And Fellows Of Harvard College Inhibiteurs hybrides de la nécroptose
WO2015014376A1 (fr) 2013-07-31 2015-02-05 Biontech Ag Diagnostic et thérapie du cancer impliquant des cellules souches cancéreuses
US9982038B2 (en) 2014-01-24 2018-05-29 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Antibodies against F glycoprotein of Hendra and Nipah viruses
WO2016062323A1 (fr) 2014-10-20 2016-04-28 Biontech Ag Methodes et compositions de diagnostic et de traitement du cancer
JO3555B1 (ar) 2015-10-29 2020-07-05 Merck Sharp & Dohme جسم مضاد يبطل فعالية فيروس الالتهاب الرئوي البشري
US10899829B2 (en) 2016-02-23 2021-01-26 Indiana University Research And Technology Corporation Emapii neutralizing antibody limits influenza A virus (IAV)-induced lung injury
US11534496B2 (en) 2016-06-07 2022-12-27 The Brigham And Women's Hospital, Inc. Compositions and methods relating to T peripheral helper cells in autoantibody-associated conditions
WO2019025299A1 (fr) 2017-07-31 2019-02-07 F. Hoffmann-La Roche Ag Procédé d'humanisation à base de structure tridimensionnelle

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4800078A (en) * 1987-05-28 1989-01-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Immunotherapeutic method of treating respiratory disease by intranasal administration of Igb

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7118866B2 (en) 1991-04-10 2006-10-10 The Scripps Research Institute Heterodimeric receptor libraries using phagemids

Also Published As

Publication number Publication date
ZA917170B (en) 1992-07-29
PT98944B (pt) 1999-02-26
KR930702519A (ko) 1993-09-09
AU654827B2 (en) 1994-11-24
JPH06501152A (ja) 1994-02-10
AU8505891A (en) 1992-03-30
PT98944A (pt) 1992-08-31
NZ239728A (en) 1995-07-26
EP0548190A1 (fr) 1993-06-30
IE913177A1 (en) 1992-03-11
MX9101046A (es) 1992-05-04
GB9019812D0 (en) 1990-10-24
WO1992004381A1 (fr) 1992-03-19

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead