CA2091335A1 - Anticorps pour la prevention et le traitement de l'infection chez les animaux et les humains - Google Patents

Anticorps pour la prevention et le traitement de l'infection chez les animaux et les humains

Info

Publication number
CA2091335A1
CA2091335A1 CA002091335A CA2091335A CA2091335A1 CA 2091335 A1 CA2091335 A1 CA 2091335A1 CA 002091335 A CA002091335 A CA 002091335A CA 2091335 A CA2091335 A CA 2091335A CA 2091335 A1 CA2091335 A1 CA 2091335A1
Authority
CA
Canada
Prior art keywords
antibody
rsv
altered
human
approximately
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002091335A
Other languages
English (en)
Inventor
William J. Harris
Philip R. Tempest
Geraldine Taylor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SCOTGEN Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2091335A1 publication Critical patent/CA2091335A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2/00Peptides of undefined number of amino acids; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1027Paramyxoviridae, e.g. respiratory syncytial virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002091335A 1990-09-11 1991-09-11 Anticorps pour la prevention et le traitement de l'infection chez les animaux et les humains Abandoned CA2091335A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9019812.8 1990-09-11
GB909019812A GB9019812D0 (en) 1990-09-11 1990-09-11 Novel antibodies for treatment and prevention of infection in animals and man

Publications (1)

Publication Number Publication Date
CA2091335A1 true CA2091335A1 (fr) 1992-03-12

Family

ID=10682003

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002091335A Abandoned CA2091335A1 (fr) 1990-09-11 1991-09-11 Anticorps pour la prevention et le traitement de l'infection chez les animaux et les humains

Country Status (12)

Country Link
EP (1) EP0548190A1 (fr)
JP (1) JPH06501152A (fr)
KR (1) KR930702519A (fr)
AU (1) AU654827B2 (fr)
CA (1) CA2091335A1 (fr)
GB (1) GB9019812D0 (fr)
IE (1) IE913177A1 (fr)
MX (1) MX9101046A (fr)
NZ (1) NZ239728A (fr)
PT (1) PT98944B (fr)
WO (1) WO1992004381A1 (fr)
ZA (1) ZA917170B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7118866B2 (en) 1991-04-10 2006-10-10 The Scripps Research Institute Heterodimeric receptor libraries using phagemids

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6750325B1 (en) 1989-12-21 2004-06-15 Celltech R&D Limited CD3 specific recombinant antibody
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
US5859205A (en) * 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
AU644210B2 (en) * 1990-07-19 1993-12-02 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Improved immunotherapeutic method of preventing or treating viral respiratory tract disease
US5994510A (en) * 1990-12-21 1999-11-30 Celltech Therapeutics Limited Recombinant antibodies specific for TNFα
CA2103059C (fr) 1991-06-14 2005-03-22 Paul J. Carter Methode de production d'anticorps humanises
WO1994004679A1 (fr) * 1991-06-14 1994-03-03 Genentech, Inc. Procede pour fabriquer des anticorps humanises
US6800738B1 (en) 1991-06-14 2004-10-05 Genentech, Inc. Method for making humanized antibodies
US5824307A (en) 1991-12-23 1998-10-20 Medimmune, Inc. Human-murine chimeric antibodies against respiratory syncytial virus
US5646253A (en) * 1994-03-08 1997-07-08 Memorial Sloan-Kettering Cancer Center Recombinant human anti-LK26 antibodies
GB9207479D0 (en) * 1992-04-06 1992-05-20 Scotgen Ltd Novel antibodies for treatment and prevention of respiratory syncytial virus infection in animals and man
US6685942B1 (en) 1993-12-10 2004-02-03 The Scripps Research Institute Human neutralizing monoclonal antibodies to respiratory syncytial virus
US5762905A (en) * 1992-09-16 1998-06-09 The Scripps Research Institute Human neutralizing monoclonal antibodies to respiratory syncytial virus
DE69419721T2 (de) 1993-01-12 2000-04-27 Biogen Inc Rekombinante anti-vla4 antikörpermoleküle
NZ269735A (en) * 1993-07-30 1998-01-26 Oravax Inc Monoclonal iga antibody against respiratory syncytial virus (rsv)
US5429746A (en) 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
US6310185B1 (en) * 1994-03-08 2001-10-30 Memorial Sloan Kettering Cancer Center Recombinant human anti-Lewis Y antibodies
WO1995031546A1 (fr) * 1994-04-28 1995-11-23 Scotgen Biopharmaceuticals, Inc. Anticorps humains recombines diriges contre le virus zosterien de la varicelle
CA2230127A1 (fr) 1995-09-18 1997-03-27 Intracel Corporation Anticorps monoclonaux neutralisants diriges contre le virus respiratorie syncytial
CA2257357C (fr) 1996-06-07 2010-04-13 Neorx Corporation Anticorps humanises a glycosylation modifiee
EP1961820B1 (fr) 1997-01-27 2012-11-28 Ludwig Institute for Cancer Research Ltd Composition vaccinale comprenant des acides nucléiques LAGE-1 associés aux tumeurs ou des polypeptides LAGE-1
DE69829293T2 (de) 1997-04-02 2006-04-13 The Brigham And Women's Hospital Inc., Boston Verwendung eines mittels zur verminderung des risikos kardiovaskulärer erkrankungen
US6160099A (en) * 1998-11-24 2000-12-12 Jonak; Zdenka Ludmila Anti-human αv β3 and αv β5 antibodies
EP1141017B1 (fr) 1998-12-30 2008-09-10 Beth Israel Deaconess Medical Center, Inc. Caracterisation d'une famille de canaux calciques
US7166573B1 (en) 1999-05-28 2007-01-23 Ludwig Institute For Cancer Research Breast, gastric and prostate cancer associated antigens and uses therefor
EP1218538A2 (fr) 1999-06-30 2002-07-03 Ludwig Institute For Cancer Research Antigenes associes au cancer et leurs utilisations
DE60044904D1 (de) 1999-09-03 2010-10-14 Brigham & Womens Hospital Verfahren und zusammensetzungen zur behandlung von entzündungskrankheiten unter verwendung von cadherin-11-modulierenden agenzien
CN1402782A (zh) 1999-10-19 2003-03-12 路德维哥癌症研究院 Mage-a12抗原肽及其应用
YU47802A (sh) * 1999-12-23 2006-03-03 Ribapharm Postupci i kompozicije za levovirin
DE10211088A1 (de) 2002-03-13 2003-09-25 Ugur Sahin Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
JP4514606B2 (ja) 2002-05-09 2010-07-28 ザ ブライハム アンド ウイメンズ ホスピタル, インコーポレイテッド 心血管疾患マーカーおよび治療標的としてのil1rl−1
DE10254601A1 (de) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
DK2325302T3 (en) 2003-02-11 2016-03-14 Shire Human Genetic Therapies Cells expressing a sulfatase and a C-formylglycine-generating enzyme and methods and uses thereof
SI2384753T1 (sl) 2003-08-29 2016-06-30 The Brigham And Women's Hospital, Inc. Hidantoinski derivati kot inhibitorji celične nekroze
DE10341812A1 (de) 2003-09-10 2005-04-07 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
DE10344799A1 (de) 2003-09-26 2005-04-14 Ganymed Pharmaceuticals Ag Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
DE102004023187A1 (de) 2004-05-11 2005-12-01 Ganymed Pharmaceuticals Ag Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
DE102004024617A1 (de) 2004-05-18 2005-12-29 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
DK1809759T3 (da) 2004-10-06 2014-01-06 Brigham & Womens Hospital Relevans af opnåede niveauer af markører for systemisk inflammation efter behandling
DE102005013846A1 (de) 2005-03-24 2006-10-05 Ganymed Pharmaceuticals Ag Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
EP1762575A1 (fr) 2005-09-12 2007-03-14 Ganymed Pharmaceuticals AG Identification d' antigènes associés aux tumeurs pour diagnose et thérapie
EP1790664A1 (fr) 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Anticorps monoclonaux contre claudin-18 pour le traitement du cancer
EP1795596A1 (fr) 2005-12-08 2007-06-13 Ganymed Pharmaceuticals AG Compositions et méthodes pour le diagnostic et la thérapie des cancers
DE102005059242A1 (de) 2005-12-12 2007-06-14 Johannes Gutenberg-Universität Mainz, Vertreten Durch Den Präsidenten Molekulare Marker für eine Tumordiagnose und -therapie
WO2007119774A1 (fr) 2006-04-13 2007-10-25 Chugai Seiyaku Kabushiki Kaisha Gène transporteur de la taurine
EP1911851A1 (fr) 2006-10-12 2008-04-16 Ganymed Pharmaceuticals AG Compositions et méthodes pour la thérapie et le diagnostic du cancer et ses métastases
EP2463304B1 (fr) 2007-02-23 2014-04-30 The United States of America as represented by the Secretary, Department of Health and Human Services Anticorps monoclonaux pour neutraliser la toxine d'anthrax
WO2008114673A1 (fr) 2007-03-15 2008-09-25 Chugai Seiyaku Kabushiki Kaisha Procédé de fabrication d'un polypeptide
ES2591284T3 (es) 2007-08-07 2016-11-25 Chugai Seiyaku Kabushiki Kaisha Método para la producción de proteínas heterogéneas
WO2009051109A1 (fr) 2007-10-15 2009-04-23 Chugai Seiyaku Kabushiki Kaisha Procédé de construction de cellules avec une productivité élevée de protéine étrangère
EP2060583A1 (fr) 2007-10-23 2009-05-20 Ganymed Pharmaceuticals AG Identification des marqueurs associés aux tumeurs pour diagnostic et thérapie
WO2009054433A1 (fr) * 2007-10-24 2009-04-30 Chugai Seiyaku Kabushiki Kaisha Cellule destinée à être utilisée dans la production de protéine exogène, et procédé de production utilisant une telle cellule
EP2108701A1 (fr) 2008-04-10 2009-10-14 Ganymed Pharmaceuticals AG Procédés comprenant MS4A12 et agents cibles MS4A12 pour thérapie, diagnostic et test
EP2318048B1 (fr) * 2008-07-21 2019-05-29 Immunomedics, Inc. Variants structuraux d'anticorps pour obtenir de meilleures caractéristiques thérapeutiques
EP2221063A1 (fr) 2009-02-20 2010-08-25 Ganymed Pharmaceuticals AG Procédé et compositions pour le diagnostic et le traitement du cancer
EP2221375A1 (fr) 2009-02-20 2010-08-25 Ganymed Pharmaceuticals AG Procédé et compositions pour le diagnostic et le traitement du cancer
US9809815B2 (en) 2009-02-20 2017-11-07 Ganymed Pharmaceuticals Ag Methods and compositions for diagnosis and treatment of cancer
WO2010123014A1 (fr) 2009-04-22 2010-10-28 中外製薬株式会社 Procédé de préparation d'une cellule capable d'une forte production de protéine hétérogène
EP2249159A1 (fr) 2009-04-29 2010-11-10 Ganymed Pharmaceuticals AG Identification des marqueurs associés aux tumeurs pour diagnostic et thérapie
CA2775373C (fr) 2009-11-11 2019-10-29 Ganymed Pharmaceuticals Ag Anticorps specifiques pour la claudine 6 (cldn6)
PT3202789T (pt) 2010-04-16 2020-06-16 Biogen Ma Inc Anticorpos anti-vla-4
WO2011133894A2 (fr) 2010-04-23 2011-10-27 Purdue Research Foundation Formulations et conditionnements de médicaments protéiques
EP2566967B1 (fr) 2010-05-04 2016-07-06 The Brigham and Women's Hospital, Inc. Antagoniste de la cadhérine-11 pour le traitement de la fibrose
EP2404936A1 (fr) 2010-07-06 2012-01-11 Ganymed Pharmaceuticals AG Thérapie du cancer utilisant des anticorps in vivo dirigés sur la cible CLDN6
CN107090043B (zh) 2011-05-13 2021-12-07 加尼梅德药物公司 用于治疗表达密蛋白6之癌症的抗体
WO2013078122A1 (fr) 2011-11-22 2013-05-30 President And Fellows Of Harvard College Diagnostic du diabète par l'intermédiaire de la détection de protéines glycatées dans l'urine
WO2013167153A1 (fr) 2012-05-09 2013-11-14 Ganymed Pharmaceuticals Ag Anticorps utiles dans le diagnostic du cancer
WO2014145022A1 (fr) 2013-03-15 2014-09-18 President And Fellows Of Harvard College Inhibiteurs hybrides de la nécroptose
WO2015014376A1 (fr) 2013-07-31 2015-02-05 Biontech Ag Diagnostic et thérapie du cancer impliquant des cellules souches cancéreuses
US9982038B2 (en) 2014-01-24 2018-05-29 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Antibodies against F glycoprotein of Hendra and Nipah viruses
WO2016062323A1 (fr) 2014-10-20 2016-04-28 Biontech Ag Methodes et compositions de diagnostic et de traitement du cancer
JO3555B1 (ar) 2015-10-29 2020-07-05 Merck Sharp & Dohme جسم مضاد يبطل فعالية فيروس الالتهاب الرئوي البشري
WO2017147258A1 (fr) 2016-02-23 2017-08-31 Indiana University Research & Technology Corporation Anticorps de neutralisation d'emapii limitant les lésions pulmonaires induites par le virus de la grippe a (iav)
US11534496B2 (en) 2016-06-07 2022-12-27 The Brigham And Women's Hospital, Inc. Compositions and methods relating to T peripheral helper cells in autoantibody-associated conditions
CN110945023B (zh) 2017-07-31 2023-08-18 豪夫迈·罗氏有限公司 基于三维结构的人源化方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4800078A (en) * 1987-05-28 1989-01-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Immunotherapeutic method of treating respiratory disease by intranasal administration of Igb

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7118866B2 (en) 1991-04-10 2006-10-10 The Scripps Research Institute Heterodimeric receptor libraries using phagemids

Also Published As

Publication number Publication date
AU654827B2 (en) 1994-11-24
EP0548190A1 (fr) 1993-06-30
PT98944B (pt) 1999-02-26
IE913177A1 (en) 1992-03-11
GB9019812D0 (en) 1990-10-24
AU8505891A (en) 1992-03-30
MX9101046A (es) 1992-05-04
KR930702519A (ko) 1993-09-09
JPH06501152A (ja) 1994-02-10
NZ239728A (en) 1995-07-26
ZA917170B (en) 1992-07-29
WO1992004381A1 (fr) 1992-03-19
PT98944A (pt) 1992-08-31

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead