CA2084834A1 - Proteins for inhibiting adhesion of platelets to collagen - Google Patents

Proteins for inhibiting adhesion of platelets to collagen

Info

Publication number
CA2084834A1
CA2084834A1 CA002084834A CA2084834A CA2084834A1 CA 2084834 A1 CA2084834 A1 CA 2084834A1 CA 002084834 A CA002084834 A CA 002084834A CA 2084834 A CA2084834 A CA 2084834A CA 2084834 A1 CA2084834 A1 CA 2084834A1
Authority
CA
Canada
Prior art keywords
collagen
protein
platelet adhesion
dna
adhesion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002084834A
Other languages
English (en)
French (fr)
Inventor
Thomas M. Connolly
Michael Neeper
Lloyd Waxman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2084834A1 publication Critical patent/CA2084834A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43527—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from ticks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/855—Proteins from animals other than mammals or birds
    • Y10S530/858—Proteins from animals other than mammals or birds insects; venom

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Insects & Arthropods (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002084834A 1991-12-10 1992-12-08 Proteins for inhibiting adhesion of platelets to collagen Abandoned CA2084834A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US807,022 1977-06-16
US07/807,022 US5321010A (en) 1991-12-10 1991-12-10 Proteins for inhibiting adhesion of platelets to collagen

Publications (1)

Publication Number Publication Date
CA2084834A1 true CA2084834A1 (en) 1993-06-11

Family

ID=25195390

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002084834A Abandoned CA2084834A1 (en) 1991-12-10 1992-12-08 Proteins for inhibiting adhesion of platelets to collagen

Country Status (4)

Country Link
US (1) US5321010A (enExample)
EP (1) EP0546813A2 (enExample)
JP (1) JPH0774235B2 (enExample)
CA (1) CA2084834A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996005304A1 (en) * 1994-08-09 1996-02-22 Athena Neurosciences, Inc. Integrin blocking molecules
US8017634B2 (en) 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
EP1931733A4 (en) * 2005-09-28 2009-11-25 Biovascular Inc METHOD AND COMPOSITIONS FOR BLOCKING THROMBOZYTE AND CELL ADHESION, CELL MIGRATION AND IGNITION
US20110034396A1 (en) * 2005-09-28 2011-02-10 Biovascular, Inc. Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions
WO2008092656A1 (en) * 2007-01-31 2008-08-07 Anders Jeppsson Use of fibrinogen as a prophylactic treatment to prevent bleeding during and after surgery and as a biomarker to identify patient with an increased risk for excessive bleeding and blood transfusion
JP2013526273A (ja) * 2010-05-14 2013-06-24 ストールハンシェ，ペール キットおよび方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3819078A1 (de) * 1988-06-04 1989-12-07 Hoechst Ag Amblyommin, ein neuer wirkstoff fuer die antikoagulationstherapie
CA2024697A1 (en) * 1989-09-07 1991-03-08 George P. Vlasuk Protein having anticoagulant properties
DE3931839A1 (de) * 1989-09-23 1991-04-04 Basf Ag Neue proteine und ihre herstellung
US5179082A (en) * 1990-11-13 1993-01-12 Merck & Co., Inc. Method for blocking platelet adhesion to collagen

Also Published As

Publication number Publication date
JPH05331197A (ja) 1993-12-14
EP0546813A2 (en) 1993-06-16
JPH0774235B2 (ja) 1995-08-09
EP0546813A3 (enExample) 1994-01-05
US5321010A (en) 1994-06-14

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Legal Events

Date Code Title Description
FZDE Discontinued