CA2066607A1 - Peptides associes a la region de liaison cd4 de la gp120 et les methodes pour les utiliser - Google Patents
Peptides associes a la region de liaison cd4 de la gp120 et les methodes pour les utiliserInfo
- Publication number
- CA2066607A1 CA2066607A1 CA002066607A CA2066607A CA2066607A1 CA 2066607 A1 CA2066607 A1 CA 2066607A1 CA 002066607 A CA002066607 A CA 002066607A CA 2066607 A CA2066607 A CA 2066607A CA 2066607 A1 CA2066607 A1 CA 2066607A1
- Authority
- CA
- Canada
- Prior art keywords
- antibodies
- hiv
- compound
- peptide
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Hematology (AREA)
- AIDS & HIV (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41106389A | 1989-09-22 | 1989-09-22 | |
| US411,063 | 1989-09-22 | ||
| US58494890A | 1990-09-18 | 1990-09-18 | |
| US584,948 | 1990-09-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2066607A1 true CA2066607A1 (fr) | 1991-03-23 |
Family
ID=27021259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002066607A Abandoned CA2066607A1 (fr) | 1989-09-22 | 1990-09-21 | Peptides associes a la region de liaison cd4 de la gp120 et les methodes pour les utiliser |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0493508A1 (fr) |
| AU (1) | AU6523590A (fr) |
| CA (1) | CA2066607A1 (fr) |
| IE (1) | IE903433A1 (fr) |
| IL (1) | IL95824A0 (fr) |
| WO (1) | WO1991004273A2 (fr) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5637677A (en) | 1987-07-16 | 1997-06-10 | The Trustees Of The University Of Pennsylvania | Biologically active compounds and methods of constructing and using the same |
| DE69029937T2 (de) * | 1989-04-25 | 1997-05-28 | Tanox Biosystems Inc | FÜr DIE CO4-BINDENDE DOMÄNE VON HIV SPEZIFISCHE ANTIKÖRPER |
| US7041293B1 (en) | 1990-04-03 | 2006-05-09 | Genentech, Inc. | HIV env antibodies |
| ATE125157T1 (de) * | 1990-04-03 | 1995-08-15 | Genentech Inc | Methoden und zusammensetzungen zur impfung gegen hiv. |
| AP237A (en) * | 1990-05-29 | 1993-04-29 | Cedars Sinai Medical Center | Immunoreagents reactive with a conserved epitope of human immunodeficiency virus type 1 (HIV-1) gp120 and methods of use. |
| CA2047042A1 (fr) * | 1990-07-19 | 1992-01-20 | John Hannah | Peptides cycliques neutralisant le vih |
| CA2047033A1 (fr) * | 1990-07-19 | 1992-01-20 | Elizabeth E. Sugg | Peptides cycliques neutralisant le vih |
| CA2047078A1 (fr) * | 1990-07-19 | 1992-01-20 | Steven S. Bondy | Peptides cycliques neutralisant le vih |
| WO1992004914A1 (fr) * | 1990-09-14 | 1992-04-02 | The Trustees Of The University Of Pennsylvania | Production de peptides bioactifs sur la base de la structure des immunoglobulines |
| JPH05262662A (ja) * | 1991-07-15 | 1993-10-12 | Calpis Food Ind Co Ltd:The | Ｈｉｖ重感染防止剤、抗イディオタイプ抗体作製用抗原及び抗イディオタイプ抗体の製造法 |
| JPH07506810A (ja) * | 1992-02-10 | 1995-07-27 | デューク・ユニバーシティ | 自己抗原である病原性のｔ細胞エピトープおよびｂ細胞エピトープに対する寛容性を誘導するための合成ペプチドの使用 |
| US5556744A (en) * | 1992-05-29 | 1996-09-17 | The Trustees Of The University Of Pennsylvania | Methods and compositions for diagnosing and treating certain HIV infected patients |
| NZ267838A (en) | 1993-06-07 | 1997-12-19 | Genentech Inc | Preparation of an hiv gp 120 subunit vaccine involving determining a neutralising epitope in the v2 and/or c4 domains |
| ATE177843T1 (de) * | 1994-01-19 | 1999-04-15 | Us Health | Peptomere mit erhöhter immunogenizität |
| DE4405810A1 (de) | 1994-02-23 | 1995-08-24 | Behringwerke Ag | Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung |
| US5691447A (en) * | 1995-03-24 | 1997-11-25 | Tanox Biosystems, Inc. | GC1q receptor, HIV-1 gp120 region binding thereto, and related peptides and targeting antibodies |
| ZA975889B (en) * | 1996-07-08 | 1998-02-23 | Genentech Inc | HIV envelope polypeptides and vaccine. |
| US6585979B1 (en) | 1996-07-08 | 2003-07-01 | Genentech, Inc. | HIV envelope polypeptides and immunogenic composition |
| DK1141315T3 (da) | 1998-12-31 | 2008-05-19 | Novartis Vaccines & Diagnostic | Modificerede HIV Env-polypeptider |
| AU2487300A (en) | 1998-12-31 | 2000-07-31 | Chiron Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| AU2221600A (en) | 1998-12-31 | 2000-07-31 | Chiron Corporation | Improved expression of hiv polypeptides and production of virus-like particles |
| AU2001254567A1 (en) * | 2000-05-02 | 2001-11-12 | Simon Fraser University | Polypeptides for use as a vaccine and/or treatment for hiv infection |
| WO2003004620A2 (fr) | 2001-07-05 | 2003-01-16 | Chiron, Corporation | Polynucleotides codant des polypeptides de type c du vih antigeniques, polypeptides et leurs utilisations |
| US20030170614A1 (en) | 2001-08-31 | 2003-09-11 | Megede Jan Zur | Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof |
| WO2007117596A1 (fr) * | 2006-04-05 | 2007-10-18 | The Regents Of The University Of California | Compositions et procédé d'analyse et de traitement du syndrome de cachexie liée au sida et de la dysfonction des cellules immunitaires |
| JP5867795B2 (ja) * | 2007-02-01 | 2016-02-24 | テーツェーエフ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 調節性ｔ細胞の特異的活性化ならびに喘息、アレルギー疾患、自己免疫疾患、移植片拒絶の治療および免疫寛容の誘導のためのその使用 |
| EP2452947A1 (fr) * | 2010-11-16 | 2012-05-16 | Münch, Jan | Peptide augmentant l'infection virale |
| EP2492279A1 (fr) | 2011-02-25 | 2012-08-29 | Laboratorios Del. Dr. Esteve, S.A. | Procédé de sélection rapide d'immunogène par expression à la surface du lentivirus. |
| EP2698377A1 (fr) | 2012-08-17 | 2014-02-19 | Laboratorios Del. Dr. Esteve, S.A. | Procédé de sélection rapide d'immunogène de variants de la GP-120 du VIH amélioré |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0762031B2 (ja) * | 1986-12-30 | 1995-07-05 | アメリカ合衆国 | エイズウイルスおよびエイズウイルスのタンパク質に対する細胞性免疫を誘導する合成ペプチド |
| EP0279688B1 (fr) * | 1987-02-20 | 1997-04-16 | Genentech, Inc. | Méthodes et compositions pour l'utilisation de polypeptides env et anticorps anti-env de HIV |
| IL87391A0 (en) * | 1987-08-27 | 1989-01-31 | Repligen Corp | Hiv proteins and peptides,dna coding therefor,vectors comprising such dna,the use of the proteins and peptides in diagnosis of aids and vaccine compositions containing them |
| CA1341285C (fr) * | 1988-02-12 | 2001-08-14 | Chang Yi Wang | Peptides synthetiques servant a la detection d'anticorps de la proteine de surface gp120 du virus hiv, destines au diagnostic du sida, ainsi que d'etats pre-sidatiques, ou aux fins de vaccins |
| EP0330359A3 (fr) * | 1988-02-25 | 1991-06-05 | Bio-Rad Laboratories, Inc. | Composition utile pour le diagnostic et le traitement de l'infection par le HIV-I |
-
1990
- 1990-09-21 AU AU65235/90A patent/AU6523590A/en not_active Abandoned
- 1990-09-21 CA CA002066607A patent/CA2066607A1/fr not_active Abandoned
- 1990-09-21 EP EP90915005A patent/EP0493508A1/fr not_active Withdrawn
- 1990-09-21 WO PCT/US1990/005393 patent/WO1991004273A2/fr not_active Application Discontinuation
- 1990-09-24 IE IE343390A patent/IE903433A1/en unknown
- 1990-09-27 IL IL95824A patent/IL95824A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1991004273A3 (fr) | 1991-05-02 |
| IE903433A1 (en) | 1991-04-10 |
| AU6523590A (en) | 1991-04-18 |
| WO1991004273A2 (fr) | 1991-04-04 |
| EP0493508A1 (fr) | 1992-07-08 |
| IL95824A0 (en) | 1991-06-30 |
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