CA2056981A1 - Inhibiteurs de croissance de tumeurs derives de tissus, methode de preparation et utilisations - Google Patents

Inhibiteurs de croissance de tumeurs derives de tissus, methode de preparation et utilisations

Info

Publication number
CA2056981A1
CA2056981A1 CA002056981A CA2056981A CA2056981A1 CA 2056981 A1 CA2056981 A1 CA 2056981A1 CA 002056981 A CA002056981 A CA 002056981A CA 2056981 A CA2056981 A CA 2056981A CA 2056981 A1 CA2056981 A1 CA 2056981A1
Authority
CA
Canada
Prior art keywords
protein
tgf
activity
tumor growth
tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002056981A
Other languages
English (en)
Inventor
Kenneth K. Iwata
John R. Stephenson
Peter Ten Dijke
Robert Franco
Leslie I. Gold
J. Gordon Foulkes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OSI Pharmaceuticals LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2056981A1 publication Critical patent/CA2056981A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA002056981A 1989-05-17 1990-05-17 Inhibiteurs de croissance de tumeurs derives de tissus, methode de preparation et utilisations Abandoned CA2056981A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35341089A 1989-05-17 1989-05-17
US353,410 1989-05-17

Publications (1)

Publication Number Publication Date
CA2056981A1 true CA2056981A1 (fr) 1990-11-18

Family

ID=23388978

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002056981A Abandoned CA2056981A1 (fr) 1989-05-17 1990-05-17 Inhibiteurs de croissance de tumeurs derives de tissus, methode de preparation et utilisations

Country Status (5)

Country Link
EP (1) EP0508983A4 (fr)
JP (1) JPH04505325A (fr)
AU (1) AU668072B2 (fr)
CA (1) CA2056981A1 (fr)
WO (1) WO1990014360A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992000318A1 (fr) * 1990-06-25 1992-01-09 Oncogene Science, Inc. Inhibiteurs de croissance de tumeurs derives de tissus, procedes de preparation et utilisations desdits inhibiteurs
EP0625989B1 (fr) * 1992-02-12 2000-01-19 BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH Sequences d'adn codant de nouveaux facteurs de croissance/differentiation
JP2000508898A (ja) * 1996-04-12 2000-07-18 アストラ・アクチエボラーグ 免疫調節作用を有するシステイン―含有またはメチオニン―含有ペプチド

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4886747A (en) * 1985-03-22 1989-12-12 Genentech, Inc. Nucleic acid encoding TGF-β and its uses
NZ222168A (en) * 1986-10-20 1991-05-28 Oncogene Science Inc Tumour growth inhibiting protein related to tgf-#b#1 and tgf-#b#2, preparation by genetic engineering methods, antibodies and pharmaceutical compositions

Also Published As

Publication number Publication date
AU668072B2 (en) 1996-04-26
EP0508983A1 (fr) 1992-10-21
EP0508983A4 (en) 1993-05-05
JPH04505325A (ja) 1992-09-17
WO1990014360A1 (fr) 1990-11-29
AU5729390A (en) 1990-12-18

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Legal Events

Date Code Title Description
FZDE Dead