EP0508983A4 - Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof - Google Patents

Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof

Info

Publication number
EP0508983A4
EP0508983A4 EP19900908325 EP90908325A EP0508983A4 EP 0508983 A4 EP0508983 A4 EP 0508983A4 EP 19900908325 EP19900908325 EP 19900908325 EP 90908325 A EP90908325 A EP 90908325A EP 0508983 A4 EP0508983 A4 EP 0508983A4
Authority
EP
European Patent Office
Prior art keywords
tissue
preparation
methods
tumor growth
growth inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19900908325
Other versions
EP0508983A1 (en
Inventor
Kenneth K. Iwata
John R. Stephenson
Peter Ten Dijke
Robert Franco
Leslie I. Gold
J. Gordon Foulkes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OSI Pharmaceuticals LLC
Original Assignee
Oncogene Science Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogene Science Inc filed Critical Oncogene Science Inc
Publication of EP0508983A1 publication Critical patent/EP0508983A1/en
Publication of EP0508983A4 publication Critical patent/EP0508983A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
EP19900908325 1989-05-17 1990-05-17 Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof Withdrawn EP0508983A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35341089A 1989-05-17 1989-05-17
US353410 1989-05-17

Publications (2)

Publication Number Publication Date
EP0508983A1 EP0508983A1 (en) 1992-10-21
EP0508983A4 true EP0508983A4 (en) 1993-05-05

Family

ID=23388978

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19900908325 Withdrawn EP0508983A4 (en) 1989-05-17 1990-05-17 Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof

Country Status (5)

Country Link
EP (1) EP0508983A4 (en)
JP (1) JPH04505325A (en)
AU (1) AU668072B2 (en)
CA (1) CA2056981A1 (en)
WO (1) WO1990014360A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2084992A1 (en) * 1990-06-25 1991-12-26 Osi Pharmaceuticals, Inc. Tissue-derived tumor growth inhibitors, methods for preparation and uses thereof
ATE188996T1 (en) * 1992-02-12 2000-02-15 Bioph Biotech Entw Pharm Gmbh DNA SEQUENCES CODING FOR NOVEL GROWTH/DIFERENTATION FACTORS
EP0923604A1 (en) * 1996-04-12 1999-06-23 Astra Aktiebolag Cysteine-containing or methioine-containing peptides with immunomodulatory effects

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0267463A2 (en) * 1986-10-20 1988-05-18 Oncogene Science, Inc. Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4886747A (en) * 1985-03-22 1989-12-12 Genentech, Inc. Nucleic acid encoding TGF-β and its uses

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0267463A2 (en) * 1986-10-20 1988-05-18 Oncogene Science, Inc. Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
EMBO JOURNAL. vol. 7, no. 12, 1988, EYNSHAM, OXFORD GB pages 3737 - 3743 R. DERYNCK ET AL 'A new type of transforming growth factor-beta , TGF-beta 3' *
MOLECULAR AND CELLULAR BIOLOGY vol. 7, no. 10, October 1987, WASHINGTON US pages 3418 - 3427 LARRY E. GENTRY ET AL 'Type 1 Transforming Growth Factor beta : amplified expression and secretion of mature and precursor polypeptides in chinese hamster ovary cells' *
See also references of WO9014360A1 *

Also Published As

Publication number Publication date
CA2056981A1 (en) 1990-11-18
AU668072B2 (en) 1996-04-26
WO1990014360A1 (en) 1990-11-29
JPH04505325A (en) 1992-09-17
EP0508983A1 (en) 1992-10-21
AU5729390A (en) 1990-12-18

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19920429

AK Designated contracting states

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A4 Supplementary search report drawn up and despatched

Effective date: 19930316

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Effective date: 19950120

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: ONCOGENE SCIENCE, INC.

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19971126