CA2011637A1 - Composes pour la liberation soutenue de chlorhexidine - Google Patents

Composes pour la liberation soutenue de chlorhexidine

Info

Publication number
CA2011637A1
CA2011637A1 CA2011637A CA2011637A CA2011637A1 CA 2011637 A1 CA2011637 A1 CA 2011637A1 CA 2011637 A CA2011637 A CA 2011637A CA 2011637 A CA2011637 A CA 2011637A CA 2011637 A1 CA2011637 A1 CA 2011637A1
Authority
CA
Canada
Prior art keywords
release
compositions
chlorhexidine
sustained
diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2011637A
Other languages
English (en)
Other versions
CA2011637C (fr
Inventor
Michael Friedman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2011637A1 publication Critical patent/CA2011637A1/fr
Application granted granted Critical
Publication of CA2011637C publication Critical patent/CA2011637C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/50—Preparations specially adapted for dental root treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
CA002011637A 1989-03-16 1990-03-07 Composes pour la liberation soutenue de chlorhexidine Expired - Fee Related CA2011637C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US324,505 1989-03-16
US07/324,505 US5002769A (en) 1987-03-13 1989-03-16 Compositions for the sustained-release of chlorhexidine

Publications (2)

Publication Number Publication Date
CA2011637A1 true CA2011637A1 (fr) 1990-09-16
CA2011637C CA2011637C (fr) 2001-01-30

Family

ID=23263888

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002011637A Expired - Fee Related CA2011637C (fr) 1989-03-16 1990-03-07 Composes pour la liberation soutenue de chlorhexidine

Country Status (9)

Country Link
US (1) US5002769A (fr)
EP (1) EP0388220B1 (fr)
JP (1) JP2960098B2 (fr)
AT (1) ATE119391T1 (fr)
AU (1) AU621521B2 (fr)
CA (1) CA2011637C (fr)
DE (1) DE69017484T2 (fr)
DK (1) DK0388220T3 (fr)
ES (1) ES2068999T3 (fr)

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US5186936A (en) * 1990-08-06 1993-02-16 Board Of Trustees Of The University Of Illinois Packing material for treatment of infections
IL97771A (en) * 1991-04-04 1996-12-05 Sion Narrow Weaving Dry polymeric material having antimicrobial activity
US5385606A (en) * 1992-07-06 1995-01-31 Kowanko; Nicholas Adhesive composition and method
US6015844A (en) * 1993-03-22 2000-01-18 Johnson & Johnson Medical, Inc. Composite surgical material
GB2280850B (en) * 1993-07-28 1997-07-30 Johnson & Johnson Medical Absorbable composite materials for use in the treatment of periodontal disease
US6001895A (en) * 1993-03-22 1999-12-14 Johnson & Johnson Medical, Inc. Composite surgical material
GB9402877D0 (en) * 1994-02-15 1994-04-06 Torchinsky Alick Mouthwash
EP0886521B1 (fr) * 1996-02-14 2003-05-21 Itzhak Binderman Bisphosphonates topiques permettant de prevenir la resorption osseuse
US6117856A (en) * 1996-02-14 2000-09-12 Binderman; Itzhak Topical bisphosphonates for prevention of bone resorption
US6197331B1 (en) 1997-07-24 2001-03-06 Perio Products Ltd. Pharmaceutical oral patch for controlled release of pharmaceutical agents in the oral cavity
DE19813686A1 (de) * 1998-03-27 1999-09-30 Roeko Gmbh & Co Antibakteriell wirksames Mittel zur Behandlung oder zum Füllen von Wurzelkanälen und Herstellungsverfahren
US7074426B2 (en) * 2002-03-27 2006-07-11 Frank Kochinke Methods and drug delivery systems for the treatment of orofacial diseases
US10098981B2 (en) 2002-08-06 2018-10-16 Baxter International Inc. Biocompatible phase invertable proteinaceous compositions and methods for making and using the same
US9101536B2 (en) 2002-08-06 2015-08-11 Matrix Medical Llc Biocompatible phase invertable proteinaceous compositions and methods for making and using the same
US20040053201A1 (en) * 2002-09-17 2004-03-18 Dovgan Joseph S. Antibacterial sponges for use in endodontic procedures and methods of use
US20040136926A1 (en) * 2002-11-08 2004-07-15 Periathamby Antony Raj Intra-oral drug delivery system
US20040185009A1 (en) * 2003-03-19 2004-09-23 Dexcel Pharma Technologies Ltd. Composition and device for treating periodontal diseases
US20050036955A1 (en) * 2003-08-13 2005-02-17 Degould Michael D. Bioresorbable tooth extraction socket dressing
US20070213768A1 (en) * 2003-10-21 2007-09-13 Irena Wasserman Compositions and Devices Including Same Useful for Anastomosis
US7678767B2 (en) 2004-06-16 2010-03-16 Pneumrx, Inc. Glue compositions for lung volume reduction
US20060002970A1 (en) * 2004-07-01 2006-01-05 Aspenberg Per V Method for coating a suture
CN101115475A (zh) * 2004-12-10 2008-01-30 塔利马治疗公司 用于治疗指甲单位病症的组合物和方法
US20060275230A1 (en) * 2004-12-10 2006-12-07 Frank Kochinke Compositions and methods for treating conditions of the nail unit
US20070160559A1 (en) * 2006-01-12 2007-07-12 Roszell James A Skin disinfectant composition and methods for using
FR2896057A1 (fr) * 2006-01-12 2007-07-13 St Microelectronics Sa Procede et dispositif de generation d'un nombre aleatoire dans un peripherique usb
WO2008100451A2 (fr) * 2007-02-09 2008-08-21 Dentsply International Inc. Procédé pour le traitement de la pulpe dentaire et de remplissage de canaux radiculaires à l'aide de matériaux à base d'eau
EP1961414A1 (fr) * 2007-02-21 2008-08-27 FUJIFILM Manufacturing Europe B.V. Composition de libération contrôlée comprenant une gélatine recombinée
EP1961411A1 (fr) * 2007-02-21 2008-08-27 FUJIFILM Manufacturing Europe B.V. Composition de libération contrôlée
WO2008103041A1 (fr) * 2007-02-21 2008-08-28 Fujifilm Manufacturing Europe B.V. Gélatines de recombinaison
US20080241795A1 (en) * 2007-03-26 2008-10-02 Block James C Prevention and treatment of alveolar osteitis
US8541047B1 (en) 2008-03-24 2013-09-24 Richard J. Shaw Polar antiseptic/antibacterial containing toothpick probes
US9468510B2 (en) 2008-03-24 2016-10-18 Richard J. Shaw Floss device, a method of forming the floss device and a method of using the floss device
WO2010026782A1 (fr) * 2008-09-08 2010-03-11 独立行政法人物質・材料研究機構 Matériau composite comprenant une matrice de masse moléculaire élevée et un composé organique de masse moléculaire faible et procédé de fabrication de celui-ci
US8735422B2 (en) * 2009-02-06 2014-05-27 Skinvisible Pharmaceuticals, Inc. Cationic pharmaceutically active ingredient containing composition, and methods for manufacturing and using
WO2010135664A1 (fr) * 2009-05-22 2010-11-25 The Trustees Of The University Of Pennsylvania Procédés d'identification et d'utilisation d'inhibiteurs d'épissage à caractère général ou autre
US20110207832A1 (en) * 2010-02-19 2011-08-25 Skinvisible Pharmaceuticals, Inc. Skin disinfectant composition and methods for manufacturing and using
US8865198B2 (en) 2010-10-25 2014-10-21 Dexcel Pharma Technologies Ltd. Method for treating a periodontal disease
DE102012001979A1 (de) 2012-02-02 2013-08-08 Voco Gmbh Härtbares Gemisch umfassend Weichmacher mit einem polyalicyclischen Strukturelement zur Anwendung bei der Herstellung dentaler Werkstoffe
DE102012001978A1 (de) 2012-02-02 2013-08-08 Voco Gmbh Dentale Kompositmaterialien enthaltend tricyclische Weichmacher
WO2014126945A1 (fr) * 2013-02-14 2014-08-21 Dentsply International Inc. Compositions résorbables et durcissables à utiliser en dentisterie
RU2015143995A (ru) 2013-03-14 2017-04-20 Халлюкс, Инк. Способ лечения инфекций, заболеваний или расстройств ногтевого ложа
EP3003285B1 (fr) * 2013-06-03 2022-02-16 McNeil AB Forme dosifiée pharmaceutique solide de libération d'au moins deux principes pharmaceutiques actifs dans la cavité buccale
SG11201604596RA (en) * 2013-12-12 2016-07-28 Innovation Technologies Inc Materials and methods for controlling infections
DE202014101882U1 (de) 2014-04-22 2014-05-02 Armin Armani Orales Abgabesystem
CZ308891B6 (cs) * 2014-10-01 2021-08-11 Wald Pharmaceuticals s.r.o Aplikační směs pro zvýšení účinnosti antiseptik a/nebo dezinficiens, aplikační prostředek obsahující aplikační směs, a použití této směsi
US10786448B2 (en) 2018-01-18 2020-09-29 Christian Arnold Chewing gum composition comprising polyhexanide
DE102019000322A1 (de) 2019-01-14 2020-07-16 Beuth Hochschule Für Technik Berlin Polymerzusammensetzung mit antiseptischen Eigenschaften und Verfahren zur Herstellung
DE102019000321A1 (de) 2019-01-14 2020-07-16 Beuth Hochschule Für Technik Berlin Orale Polymerzusammensetzung mit verzögerter Freisetzung
CN110124099B (zh) * 2019-06-14 2022-01-11 四川涑爽医疗用品有限公司 一种长效抑菌的复配牙周塞治剂及其制备方法
DE102019122174A1 (de) 2019-08-19 2021-02-25 Voco Gmbh Dentale polymerisierbare Zusammensetzung auf der Basis kondensierter Silane
DE102020007979A1 (de) 2020-12-29 2022-06-30 Charité Universitätsmedizin Institut für Mikrobiologie und Infektionsimmunologie Zusammensetzung zur Behandlung von lnfektionen mit Coronaviren

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2961374A (en) * 1950-10-14 1960-11-22 Lieb Hans Injectable pharmaceutical preparation, and a method of making same
US3642003A (en) * 1969-08-26 1972-02-15 Sutures Inc Sutures having long-lasting germicidal properties
US3956480A (en) * 1974-07-01 1976-05-11 Colgate-Palmolive Company Treatment of teeth
US4344967A (en) * 1979-08-07 1982-08-17 Devro, Inc. Film forming composition and uses thereof
US4568535A (en) * 1982-08-06 1986-02-04 Loesche Walter J Composition for periodontal administration
JPS59222406A (ja) * 1983-06-01 1984-12-14 Teijin Ltd 歯周疾患治療用製剤及びその製造法
US4758595A (en) * 1984-12-11 1988-07-19 Bausch & Lomb Incorporated Disinfecting and preserving systems and methods of use
FR2591892B1 (fr) * 1985-12-23 1988-09-16 Pf Medicament Association collagene/principe actifantiseptique et/ou anti-inflammatoire a titre de composition, son procede de preparation et son utilisation pour la fabrication d'une composition pharmaceutique
JPS62223115A (ja) * 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤
IL78826A (en) * 1986-05-19 1991-05-12 Yissum Res Dev Co Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom

Also Published As

Publication number Publication date
ATE119391T1 (de) 1995-03-15
DE69017484D1 (de) 1995-04-13
ES2068999T3 (es) 1995-05-01
AU621521B2 (en) 1992-03-12
AU5118990A (en) 1990-09-20
US5002769A (en) 1991-03-26
EP0388220A3 (fr) 1991-03-13
DK0388220T3 (da) 1995-03-27
JPH03200726A (ja) 1991-09-02
CA2011637C (fr) 2001-01-30
JP2960098B2 (ja) 1999-10-06
EP0388220B1 (fr) 1995-03-08
EP0388220A2 (fr) 1990-09-19
DE69017484T2 (de) 1995-07-27

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed